What's Biomolecular Rocket?
- We propose an extremely high-speed, controllable and rail-free molecular vehicle, "Biomolecular Rocket." The Biomolecular Rocket moves faster than a natural high-speed molecular motor, kinesin, by taking advantage of catalytic O2 production that progresses anywhere in a dilute H2O2 solution. For increasing the emission of O2 bubbles from the Biomolecular Rocket, we conjugated numerous catalytic engines to a micrometer-sized rocket body with the use of DNA. In addition, direction of the rail-free movement of the Biomolecular Rocket can be controlled, since we designed a photoresponsive DNA for allowing detachment of the engines from the body upon the UV light irradiation in a region-specific manner.
- The present study embodies the concept to utilize and control non-biological reactions by designing biomolecules for achieving novel functions implemented by synthetic molecular systems. We believe that our Biomolecular Rocket is a step toward advanced molecular robots that can move on long and rugged fields such as the inside of human body.