Biomod/2012/Tohoku/Team Sendai/test: Difference between revisions
Naito Ushio (talk | contribs) No edit summary |
Naito Ushio (talk | contribs) No edit summary |
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div#sidebar-main{ | div#sidebar-main{ | ||
visibility:hidden; | visibility:hidden; | ||
margin:-145px; | |||
} | } | ||
body{ | body{ | ||
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margin-left:- | margin-left:0 auto; | ||
position:absolute; | |||
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margin:0 0 0 -775px; | |||
} | } | ||
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/* トップメニュー */ | /* トップメニュー */ | ||
ul#Topmenu {font-size: | ul#Topmenu {font-size: 30px; | ||
margin-top: 0; | margin-top: 0; | ||
margin-bottom: 30px; | margin-bottom: 30px; | ||
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ul#Topmenu li a:hover {background-color: # | ul#Topmenu li a:hover {background-color: #00aa00} | ||
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margin-bottom: 2px; | margin-bottom: 2px; | ||
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ul#Menu2 li a:hover {background-color: # | ul#Menu2 li a:hover {background-color: #00aa00} | ||
/*目次*/ | /*目次*/ | ||
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margin-left: auto; | margin-left: auto; | ||
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div#Content p {font-size: 20px; | |||
line-height:19px; | |||
margin: 20px 5px; | |||
width:600px; | |||
/*line-height:20px;*/} | |||
/* | /* | ||
div#Content h2 { background-color: # f5f5dc; | div#Content h2 { background-color: # f5f5dc; | ||
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margin-top: 20px; | margin-top: 20px; | ||
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margin-left: 12px; | margin-left: 12px; | ||
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/* フッター */ | /* フッター */ | ||
div#Footer {color: #ffffff; | div#Footer {color: #ffffff; | ||
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margin-top: 20px; | margin-top: 20px; | ||
margin-bottom: 4px; | margin-bottom: 4px; | ||
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font-color:white; | |||
} | } | ||
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</style> | </style> | ||
</head> | </head> | ||
<body | <body> | ||
<!-- コンテナ --> | <!-- コンテナ --> | ||
<div id="Container"> | <div id="Container"> | ||
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<!-- ヘッダー --> | <!-- ヘッダー --> | ||
<div id="Header"> | <div id="Header"> | ||
<h1><!--Team Sendai--><img src="http://openwetware.org/images/c/c2/Title-kai.png"></h1> | <h1 style="margin-top:-50px;"><!--Team Sendai--><img src="http://openwetware.org/images/c/c2/Title-kai.png" ></h1> | ||
<p>Tohoku University</p> | <p>Tohoku University</p> | ||
</div> | </div> | ||
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<!—トップメニュー --> | <!—トップメニュー --> | ||
<ul id="Topmenu"> | <ul id="Topmenu"> | ||
<li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai">Top</a></li> | <li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai" style="background-color: #00aa00;">Top</a></li> | ||
<li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> | <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> | ||
<li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> | <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> | ||
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<!-- コンテンツ --> | <!-- コンテンツ --> | ||
<div id="Content"> | <div id="Content"> | ||
<div id="pop"> | <div id="pop"> | ||
<h2>Abstract</h2> | <h2><!--Abstract-->Project Image</h2> | ||
<img src="http://openwetware.org/images/4/46/Format_D-Heart.jpg" alt="D-Heart" width="550px"><br> | <img src="http://openwetware.org/images/4/46/Format_D-Heart.jpg" alt="D-Heart" width="550px"><br> | ||
< | </div> | ||
<div id="pop"> | <div id="pop"> | ||
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<br><br> | <br><br> | ||
<p style="text-align:center;"> | <p style="text-align:center;"> | ||
<table style="width:550px;height:400px;background-color:# | <table style="border-style:solid;border-width:10px;width:550px;height:400px;background-color:black;border-color:#bbb;text-align:center;valign:middle;font-color:white;"> | ||
<tr> | <tr> | ||
<td>Coming soon...</td> | <td style="color:white;">Coming soon...</td> | ||
</tr> | </tr> | ||
</table> | </table> | ||
</p> | </p> | ||
</div> | </div> | ||
<p style="width:1200px;clear:left;margin:15px;"> | |||
All the creatures on Earth are made of cells. The exterior and the interior of the cell are compartmentalized by biomembranes. | |||
A nanodevice that is able to actively transport only the specific oligonucleotide through the biomembrane has a great potential to deliver siRNA into the cell or to extract mRNA expressed in the cell.<br> | |||
Here, we decided to create a novel device with such a function. <br> | |||
We have designed a cylindrical injector/extractor device made of DNA origami. Inside the cylinder, a cascade of single stranded DNAs is planted. Once the outer-most ssDNA binds to a target oligonucleotide, the target is passed to the inner-ones one by one because of the higher bonding energy assigned to the inner ones.<br> | |||
We also investigate how the cylinder penetrates the biomembrane by using liposome as a model membrane.<br> | |||
<br> | |||
<strong>Selector</strong>: Single stranded DNA. Once the outer-most ssDNA binds to a target, the target is passed to the inner-ones one by one.</br> | |||
<strong>Gate</strong>: Cylindrical structure connecting the inside and outside like gates. A cascade of the "Selector" is planted in this. We can use this as an injector or extractor.</br> | |||
<strong>Membrane</strong>: The exterior and the interior of the cell are compartmentalized by biomembranes. We use liposome as a model membrane.</br> | |||
</p> | |||
</div> | </div> | ||
<!—フッターメニュー --> | <!—フッターメニュー --> | ||
<ul id="Menu2"> | <ul id="Menu2"> | ||
<li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai">Top</a></li> | <li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai" style="background-color:#0a0;">Top</a></li> | ||
<li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> | <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> | ||
<li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> | <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> | ||
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</div> | </div> | ||
<a href="http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project/test">project/test</a> | |||
</body> | </body> | ||
</html> | </html> |
Latest revision as of 02:52, 19 October 2012
<html xmlns="http://www.w3.org/1999/xhtml"> <head> <meta http-equiv="Content-Type" content="text/html;charset=utf-8" /> <title>Team Sendai Top</title> <style type="text/css">
div#sidebar-main{ visibility:hidden; margin:-145px; }
body{ width:1400px; margin-left:0 auto; position:absolute; left:50%; margin:0 0 0 -775px; }
a {color: #017acd}
/* コンテナ */ div#Container {width: 1200px; margin-left: auto; margin-right: auto}
/* ヘッダー */ div#Header {background-color: #ffffff; padding: 28px 20px 28px}
div#Header h1 {color: #006600;
font-size: 80px; text-align: center; margin: 0;
font-family:'Scripx';}
div#Header p {color: #006600; font-size: 20px;
text-align: center;
margin: 0}
/* トップメニュー */ ul#Topmenu {font-size: 30px; margin-top: 0; margin-bottom: 30px; margin-left: 0; padding-left: 0; height: 30px; background-color: #fff; height:30px;}
ul#Topmenu li {list-style-type: none; float: left; padding:0; margin:0; display:block}
ul#Topmenu li a {display: block; width: 199px; line-height: 30px; text-decoration: none; text-align: center; color: #ffffff; background-color: #006600; border-right: solid 1px #ffffff}
ul#Topmenu li a:hover {background-color: #00aa00}
/* フッターメニュー */ ul#Menu2 {font-size: 30px; margin-top: 30px; margin-bottom: 2px; margin-left: 0; padding-left: 0; height: 30px; background-color: #fff; clear:left;}
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ul#Menu2 li a {display: block; width: 199px; line-height: 30px; text-decoration: none; text-align: center; color: #ffffff; background-color: #006600; border-right: solid 1px #ffffff}
ul#Menu2 li a:hover {background-color: #00aa00}
/*目次*/ div#mokuji {width: 1200px; margin-left: auto; margin-right: auto; background-color: #f5f5dc}
div#mokuji h2 { background-color: # f5f5dc; font-size: 24px; color: #000000; line-height: 45px; padding-left: 12px; margin-bottom: 0; }
ol#mokuji {font-size: 16px; margin-left: 0; padding-left: 0}
/* コンテンツ */
div#Content {width: 1200px;
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margin-right: auto}
div#Content p {font-size: 20px; line-height:19px; margin: 20px 5px; width:600px; /*line-height:20px;*/}
/*
div#Content h2 { background-color: # f5f5dc;
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div#Content h3 {background-color: #ffffff; background-image: url(maru-skyblue.png); background-repeat: no-repeat; background-position: 0px 2px; font-size: 14px; line-height: 22px; padding-left: 26px; margin-top: 30px; margin-bottom: 0; margin-left: 12px; margin-right: 12px}
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}
</style>
</head>
<body>
<!-- コンテナ -->
<div id="Container">
<!-- ヘッダー --> <div id="Header"> <h1 style="margin-top:-50px;"><!--Team Sendai--><img src="http://openwetware.org/images/c/c2/Title-kai.png" ></h1> <p>Tohoku University</p> </div>
<!—トップメニュー --> <ul id="Topmenu"> <li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai" style="background-color: #00aa00;">Top</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Results_%26_Discussion">Experiment</a></li> <li><a href=" http://openwetware.org/wiki/BIOMOD/2012/Team_Sendai/Movie">Diary</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Member ">Team</a></li> </ul>
<!-- コンテンツ --> <div id="Content">
<div id="pop">
<h2><!--Abstract-->Project Image</h2>
<img src="http://openwetware.org/images/4/46/Format_D-Heart.jpg" alt="D-Heart" width="550px"><br>
</div>
<div id="pop">
<h2>Movie</h2>
<!--
<p>Coming soon</p>
-->
<br><br>
<p style="text-align:center;">
<table style="border-style:solid;border-width:10px;width:550px;height:400px;background-color:black;border-color:#bbb;text-align:center;valign:middle;font-color:white;">
<tr>
<td style="color:white;">Coming soon...</td>
</tr>
</table>
</p>
</div>
<p style="width:1200px;clear:left;margin:15px;">
All the creatures on Earth are made of cells. The exterior and the interior of the cell are compartmentalized by biomembranes.
A nanodevice that is able to actively transport only the specific oligonucleotide through the biomembrane has a great potential to deliver siRNA into the cell or to extract mRNA expressed in the cell.<br>
Here, we decided to create a novel device with such a function. <br>
We have designed a cylindrical injector/extractor device made of DNA origami. Inside the cylinder, a cascade of single stranded DNAs is planted. Once the outer-most ssDNA binds to a target oligonucleotide, the target is passed to the inner-ones one by one because of the higher bonding energy assigned to the inner ones.<br>
We also investigate how the cylinder penetrates the biomembrane by using liposome as a model membrane.<br>
<br>
<strong>Selector</strong>: Single stranded DNA. Once the outer-most ssDNA binds to a target, the target is passed to the inner-ones one by one.</br>
<strong>Gate</strong>: Cylindrical structure connecting the inside and outside like gates. A cascade of the "Selector" is planted in this. We can use this as an injector or extractor.</br>
<strong>Membrane</strong>: The exterior and the interior of the cell are compartmentalized by biomembranes. We use liposome as a model membrane.</br>
</p>
</div>
<!—フッターメニュー --> <ul id="Menu2"> <li><a href=" http://openwetware.org/wiki/Biomod/2012/Tohoku/Team_Sendai" style="background-color:#0a0;">Top</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project">Project</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Simulation">Simulation</a></li> <li><a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Results_%26_Discussion">Experiment</a></li> <li><a href=" http://openwetware.org/wiki/BIOMOD/2012/Team_Sendai/Movie">Diary</a></li> <li><a href="http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Member ">Team</a></li> </ul>
<!-- フッター --> <div id="Footer"> <address>Copyright (C) Team Sendai, All rights reserved.</address> </div>
<a href=" http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Top
">Legacy--Team Sendai B HP</a> </div>
<a href="http://openwetware.org/wiki/Biomod/2012/TeamSendaiA/Project/test">project/test</a> </body> </html>