Biomod/2012/UCSD/tRiton Nano Architects/Brainstorm

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  <li class='active has-sub '><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects'><span>Home</span></a>
     <ul>
        <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects#Abstract:_Fluorescent_DNA_Aptamer_for_lysozyme_detection'><span>Abstract</span></a></li>
        <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects#Video'><span>Video</span></a></li>
     </ul>
  </li>
  <li class='has-sub '><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Project_introduction'><span>Project Introduction</span></a>
     <ul>
        <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Project_introduction#Concepts'><span>Concepts</span></a></li>
     </ul>
  </li>
  <li class='has-sub '><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Experiment'><span>Experiment</span></a>
     <ul>
        <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Experiment#Methods'><span>Methods</span></a></li>
     </ul>
  </li>
  <li class='has-sub '><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Resources'><span>Supplementary Resources</span></a>
     <ul>
        <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Brainstorm#DNA_architecture_log'><span>DNA Architecture Log</span></a></li>
        <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Brainstorm#Project_Ideas'><span>Project Ideas</span></a></li>
        <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Literature'><span>Literature</span></a></li>
     </ul>
  </li>
  <li><a href='http://openwetware.org/wiki/Biomod/2012/UCSD/tRiton_Nano_Architects/Team'><span>Team</span></a></li>

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Our Brainstorming Log

The tRiton Nano Architect spent a large effort in brainstorming project ideas from April 2012 to July 2012. Our effort help us learn the process of DNA nanotechnology as well as the current research stage of DNA nanotechnology. We analyzed various scientific papers cited from the resource section of past BIOMOD 2011 teams. With this knowledge, the project scope and project budget was taken into consideration when selecting our actual project/abstract.

Architecture Components Uses Technique Source

DNA box with lid

text for row 1, column 2 text for row 1, column 3 text for row 1, column 3 http://www.nature.com/nature/journal/v459/n7243/full/nature07971.html

DNA tetrahedron

text for row 2, column 2 text for row 2, column 3 text for row 1, column 3 http://pubs.rsc.org/en/Content/ArticleLanding/2004/CC/b402293a

DNA octahedron

text for row 2, column 2 text for row 2, column 3 text for row 1, column 3 http://www.nature.com/nature/journal/v427/n6975/full/nature02307.html

DNA bipyramid

text for row 2, column 2 text for row 2, column 3 text for row 1, column 3 http://pubs.acs.org/doi/abs/10.1021/ja071493b

DNA walker

text for row 2, column 2 text for row 2, column 3 text for row 1, column 3 http://www.nature.com/nnano/journal/v5/n11/full/nnano.2010.190.html

DNA dolphins with flexible tails

text for row 2, column 2 text for row 2, column 3 text for row 1, column 3 http://pubs.acs.org/doi/abs/10.1021/nn800215j

Biochemical Aptamers

text for row 2, column 2 text for row 2, column 3 text for row 1, column 3 http://en.wikipedia.org/wiki/Aptamer, http://www.sciencedirect.com/science/article/pii/S0003269701951693

DNA computational circuits

Many structural versions of this design were contemplated but the most popular structure was interlocking rings of DNA in a Y shape, which would be connected to two electrodes at one end and one at the other. On one of the Ys would contain aDNAzyme, so cleavage of that strand of DNA would occur when a trigger of a specific DNA sequence was added. DNA, DNAzymes, electrodes The idea was that this could be used in sensing. Once the target sequence of DNA (ie, a specific virus) was present, the DNAzyme would break, and the current across the chain would change. DNA attachment chemistry: http://journals.ohiolink.edu/ejc/article.cgi?issn=07437463&issue=v15i0019&article=6541_eirodfgu

DNA rings: http://www.pnas.org/content/105/14/5289 Conductivity: http://www.nature.com/nature/journal/v403/n6770/full/403635a0.html

DNA topological structures

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DNA shapes – curved and twisted

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Liquid Crystal

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DNA molecular robots [spider]

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DNA origami tubes

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Complex weaves

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