Biomod/2012/UTokyo/UT-Hongo: Difference between revisions
| Line 11: | Line 11: | ||
[[Image:Biomod-2012-UTokyo-UT-Hongo-Idia-1.jpg|center]] | [[Image:Biomod-2012-UTokyo-UT-Hongo-Idia-1.jpg|center]] | ||
FIg. 1 Schematic of Medical DNA Shell system | |||
Revision as of 04:53, 2 September 2012
<html> <head> <style> <!-- HIDE WIKI STUFF -->
- column-one { display:none; width:0px;}
.container{background-color: #ffffff; margin-top:0px} .OWWNBcpCurrentDateFilled {display: none;}
- content { width: 0px; margin: 0 auto auto 0; padding: 0em 0em 0em 0em; align: center;}
- column-content {width: 0px; float: left; margin: 0 0 0 0;padding: 0;}
.firstHeading {display:none; width:0px;}
- globalWrapper{width:984px; background-color: #ffffff; margin-left: auto; margin-right: auto}
- column-one {display:none; width:0px;background-color: #ffffff;}
- content{ margin: 0 0 0 0; align: center; padding: 12px; width: 960px;background-color: #ffff; border: 0;}
- bodyContent{ width: 960px; align: center; background-color: #ffffff;}
- column-content{width: 984px;background-color: #ffff;}
- footer{display: none; position: center; width: 960px}
@media screen {
body { background: #ffffff url(http://openwetware.org/images/1/14/Biomod-2012-utokyo-uthongo-wrapper-bg.jpg) repeat; }
}
</style>
<style>
- {
text-shadow: 0px 1px 2px #aaa; }
- bodyContent, #column-content, #content {
background: #ffffff url(http://openwetware.org/images/1/14/Biomod-2012-utokyo-uthongo-wrapper-bg.jpg) repeat; }
- column-content {
border-left: 1px solid #888; border-right: 1px solid #888;
}
- header {
width: 960px; height: 304px; background: url(http://openwetware.org/images/3/3b/Biomod-2012-UTokyo-UT-Hongo_header_test2.png) no-repeat; background-size: 100% auto; margin-bottom: 0px; padding: 0px 0px 0px 0px;
/* border-bottom: 1px solid #DEDEDE; */ }
- menu {
display: block; width: 956px; padding: 0px; background-color: black; border: 2px solid #888; margin-bottom: 15px;
}
ul.menu li a {
display: block;
/* border: 1px solid #474655; */
padding: 8px 10px; text-decoration: none;
/* color: #333; */
color: #fff;
/* width: 121px; */
margin: 0px; text-align: center; font-size: large;
}
ul.menu li a:hover{
color: cyan;
}
ul.menu { /* display: none;
position: absolute; */ height: 40px; margin:0; padding:0; list-style:none; float: center;
}
ul.menu li { /* display:inline;*/
margin:0; padding:6px; float: left; position: relative;
}
ul.menu li:hover ul {
display: block; position: absolute; z-index: 100;
}
ul.submenu {
display: none; list-style: none; background-color: #f0f0f0; border: 1px solid #ccc;
}
ul.submenu li {
float: none; margin: 0px;
}
ul.submenu li a {
text-align: left; margin: 0px; width: 340px; padding: 0 0 0 12px; color: black; text-decoration: none; font-size: large
}
ul.submenu li a:hover {
color: black; text-decoration: underline;
}
.thumb {
border-image: url(http://openwetware.org/images/1/14/Biomod-2012-utokyo-uthongo-wrapper-bg.jpg) repeat;
}
.mytable {
border-image: url(http://openwetware.org/images/1/14/Biomod-2012-utokyo-uthongo-wrapper-bg.jpg) repeat;
}
</style> </head> <body>
<!--<div style="text-align: right"> <p><a href="http://openwetware.org/index.php?title=Template:Biomod/2012/UTokyo/UT-Hongo&action=edit">edit this header</a></p> </div>-->
<div style="height: 60px; margin-bottom: 18px;">
<div style="float: left; width: 250px; padding: 3px; background-color: white;">
<a href="http://biomod.net/"><img src="http://openwetware.org/images/8/82/Biomod2012-logo.png" width="250px" height="50px"></img></a>
</div>
<div style="float: right; width: 240px; padding: 3px; background-color: white;">
<a href="http://www.u-tokyo.ac.jp/en/" target="_blank"><img src="http://www.u-tokyo.ac.jp/en/images/banner/UT-logo.gif" width="234" height="60" border="0" alt="The University of Tokyo"></img></a>
</div>
</div>
<div id="header"> </div>
<div id="menu">
<ul class="menu">
<li class="toppage"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo">Top</a></li> <li class="motives"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Intro">Motives</a></li> <!-- <li class="design"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Function">Design</a></li> --> <li class="result"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Assembly">Design & Results</a> <ul class="submenu"> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Assembly#Assembly_of_the_DNA_Shell">Assembly of the DNA Shell</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Assembly#Capturing_ability">Capturing Ability</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Assembly#Immobilizing_on_microfluidic_device">Immobilizing on microfluidic device</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Assembly#Supporting_Enzyme">Supporting Enzyme</a></li> </ul> </li> <li class="method"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Method">Method</a></li> <li class="futurework"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/FutureWork">Progress & Beyond</a></li> <li class="team"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Team">Team</a></li> <li class="acknowledgement"><a href="/wiki/Biomod/2012/UTokyo/UT-Hongo/Acknowledgement">Acknowledgement</a></li>
</ul> </div>
</body> </html>
Abstract
Methodologies to apply DNA for building precisely controlled nanostructures have greatly developed over the recent years. Our focus for BIOMOD is to utilize DNA to make a shell like structure which can capture molecules inside the shell-like body, as if a shellfish is eating its prey. Entrapment of the substrate was detected by the numerous florescent molecules that are attached to the body. This research may become a foundation for using DNA to mimic catalytic activity of enzymes.
Medical functions such as detection of diseases with small amount of blood are possible by using microfluidics. For example, detecting and sensing the concentration of Thrombin which causes blood coagulation is possible by using Shell and microfluidics developed by our team. In the future, we will develop medical DNA Shell system for monitoring components of blood, detecting diseases, inputting medicine by DNA Shell, computing system integrated in microfluidics.
FIg. 1 Schematic of Medical DNA Shell system
