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[[Image:Biomod_2012_UTokyo_UT-Komaba_Experiment_ModifiedOrigamiConcept.png|center|Modified Origami Concept]]
[[Image:Biomod_2012_UTokyo_UT-Komaba_Experiment_ModifiedOrigamiConcept.png|center|Modified Origami Concept]]


We combine DNA origami and hammerhead structure so that, when cover DNAs hybridize to the structure, the surface of the modified origami show a picture.
We combine DNA origami and pseudo-hammerhead structure so that, when cover DNAs hybridize to the structure, the hammerhead forms and the surface of the modified origami shows a picture.
Therefore, if we can set up the bistable system so that it produces the cover DNAs for different images, we can realize the DNA tablet.
Therefore, if we can set up the bistable system so that it produces the cover DNAs for different images, we can realize the DNA tablet.
The purpose of the experiment is to make sure that the hammerhead structure DNAs do not disturb during annealing in PCR.
The purpose of the experiment is to make sure that the additional single strand necessary for the hammerhead structure DNAs do not disturb during annealing in PCR.
We observe the modified DNA origami with cover DNA by AFM.
We observe the modified DNA origami with cover DNA by AFM.


==Experiment==
==Experiment==

Revision as of 02:00, 23 October 2012

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<div id="title"><img src="http://openwetware.org/images/4/47/Biomod_2012_UTokyo_UT-Komaba_Top.png" alt="DNA tablet" width="800" height="120" onClick="this.src='http://openwetware.org/images/7/7d/BIOMOD_2012_UTokyo_UT-Komaba_title-animation.gif'"/></div>

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 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Experiment">Experiment</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Progress">Progress</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Episode">Episode</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Team">Team</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Supplementary">Supplementary</a></li>

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Concept

Modified Origami Concept
Modified Origami Concept

We combine DNA origami and pseudo-hammerhead structure so that, when cover DNAs hybridize to the structure, the hammerhead forms and the surface of the modified origami shows a picture. Therefore, if we can set up the bistable system so that it produces the cover DNAs for different images, we can realize the DNA tablet. The purpose of the experiment is to make sure that the additional single strand necessary for the hammerhead structure DNAs do not disturb during annealing in PCR. We observe the modified DNA origami with cover DNA by AFM.

Experiment

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