Biomod/2012/UTokyo/UT-Komaba/Idea: Difference between revisions

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The DNA tablet shows you the two different pictures in response to its environmental change.
The DNA tablet shows you the two different pictures in response to its environmental change.


[the basic idea of DNA tablet, (including the way of applying bistable system)]
There are four kinds of pixels:
;<math>\theta</math> : always light up
;<math>\phi</math>: always black out
;<math>\overline{A}</math>: light up when there is A
;<math>\overline{B}</math>: light up when there is B
 
These pixels are actually DNA strands, and they light up when they hybridize. Please note that both α and β don't light up at the same time, because bistable system makes the state "There is only A" or "There is only B" .

Revision as of 05:01, 1 September 2012

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<div id="title"><img src="http://openwetware.org/images/4/47/Biomod_2012_UTokyo_UT-Komaba_Top.png" alt="DNA tablet" width="800" height="120" onClick="this.src='http://openwetware.org/images/7/7d/BIOMOD_2012_UTokyo_UT-Komaba_title-animation.gif'"/></div>

<div id="navi"> <ul> 

 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba">Home</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Idea">Idea</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Simulation">Simulation</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Experiment">Experiment</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Progress">Progress</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Episode">Episode</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Team">Team</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Supplementary">Supplementary</a></li>

</ul> </div>

</html>

Mission

Now that there are many tablet computers, our goal is to create the world's smallest tablet ! We are designing and constructing 15x15 pixel display made of DNA origami. We aim to show animation on that display, using bistable system.

Bistable System

What is Bistable System?

network of bistable system

Bistable system enables us to express two exclusive states, using network of chemical reaction.

For example, we represent two states by materials A and B. Bistable system uses reaction network like right picture. In this network, A promotes production of A itself and iB(i means inhibition), and B promotes B itself and iA. On the other hand, iA inhibits production of A and iB inhibits production of B. There are also reactions that decompose A, B, iA, and iB.

If A is even bit more than B, this network promotes production of A and decomposition of B (detail is shown in Simulation). Afterwards there will be only A and vice versa. Thus bistable system make two states "There is only A" and "There is only B".

Method

To realize bistable system, we used DNA.

  • production of A,B,iA,iB

So is B and iA.

  • inhibition of production of A,B

So is B.

  • decomposition of A,B,iA,iB

DNA tablet

The mechanics of displaying pixel

The DNA tablet shows you the two different pictures in response to its environmental change.

There are four kinds of pixels:

[math]\displaystyle{ \theta }[/math]
always light up
[math]\displaystyle{ \phi }[/math]
always black out
[math]\displaystyle{ \overline{A} }[/math]
light up when there is A
[math]\displaystyle{ \overline{B} }[/math]
light up when there is B

These pixels are actually DNA strands, and they light up when they hybridize. Please note that both α and β don't light up at the same time, because bistable system makes the state "There is only A" or "There is only B" .

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