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        <h2>Future</h2>
 
The advantage of our system is that large quantity of substances can be released at the desired timing and place. <br>
<h2>Future</h2>
Utilizing our system, we can note the effective treatment for cancer. Controlling the timing and place would prevent the side effects by anti-cancer agent, and releasing large amount of drug by a small quantity of triggers offers the effective treatment for cancer.<br>
Lipo-Hanabi is able to release a lot of molecules anytime and anywhere.
Such versatility is essential in potential applications as follows.<br>
 
 
<br><br>
 
<h3>Example 1 Sensing and curing inflammations in blood vessels</h3>
Inflammation in blood vessels is a typical symptom difficult to diagnose. Therefore, they could get worse while you don’t even notice it.<br>
The only way to detect blood vessel inflammation is to do a constant physical checkup. Lipo-Hanabi enables us to detect inflammations easily and gives us enough time to cure them. <br>
Specific design will be as follows. C-reactive protein (CRP) is released in the inflammation. So we can use Liposomes conjugated with phosphorylcholine (one of phosphatides react with CRP) as the 1st stage detector for Lipo-Hanabi system. Then the 2nd stage liposomes release medicine at inflammation area effectively.<br>
 
Applications of Lipo-Hanabi are not limited to inflammations. As it can sense even very faint trigger signal and release large amount of drugs, it would help us to detect cancer cells in early stage while they are curable with small amount of anti-cancer agents.<br><br>
 
 
<br>
<br>
Moreover, focusing on the chain reaction, our system can be applied to long-lasting batteries for molecular engines. If some fuel for molecular engines (such as ATP) is packed inside the liposome, and the liposome is combined with some molecular motors (such as motor proteins), the fuel can be constantly supplied to the molecular motor by only one time initiation of the reaction. <br>
<div align="center">
The molecular motor would lead to molecular engines, and in the end, sophisticated molecular robots. Our system would make it possible to achieve molecular robots moving without continuous fuel supply from the outside.<br>
<img src="http://openwetware.org/images/b/b9/%E3%83%97%E3%83%AD%E3%82%B8%E3%82%A7%E3%82%AF%E3%83%88%EF%BC%92lkjg.png" width="65%" height="65%"><br>
Fig.1 Sensing and curing inflammations in blood vessels
</div>
 
 
 
 
<h3>Example 2 molecular fuel supply</h3>
 
Focusing on the chain-reaction, Lipo-Hanabi can be applied to long-lasting batteries for molecular engines. If fuel for the molecular engines (such as ATP) is packed inside the liposome, they can constantly supply fuels to the molecular motor by a specific external signal. This kind of fuel supply system will be very useful to realize self-sustained molecular robots in the future.<br>
 
<div align="center">
<img src="http://openwetware.org/images/6/6a/Molecular-engineklug.png" width="95%" ><br>
Fig. 2 Molecular fuel supply system</div>


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<h2>Future</h2> Lipo-Hanabi is able to release a lot of molecules anytime and anywhere. Such versatility is essential in potential applications as follows.<br>


<br><br>

<h3>Example 1 Sensing and curing inflammations in blood vessels</h3> Inflammation in blood vessels is a typical symptom difficult to diagnose. Therefore, they could get worse while you don’t even notice it.<br> The only way to detect blood vessel inflammation is to do a constant physical checkup. Lipo-Hanabi enables us to detect inflammations easily and gives us enough time to cure them. <br> Specific design will be as follows. C-reactive protein (CRP) is released in the inflammation. So we can use Liposomes conjugated with phosphorylcholine (one of phosphatides react with CRP) as the 1st stage detector for Lipo-Hanabi system. Then the 2nd stage liposomes release medicine at inflammation area effectively.<br>

Applications of Lipo-Hanabi are not limited to inflammations. As it can sense even very faint trigger signal and release large amount of drugs, it would help us to detect cancer cells in early stage while they are curable with small amount of anti-cancer agents.<br><br>


<br> <div align="center"> <img src="http://openwetware.org/images/b/b9/%E3%83%97%E3%83%AD%E3%82%B8%E3%82%A7%E3%82%AF%E3%83%88%EF%BC%92lkjg.png" width="65%" height="65%"><br> Fig.1 Sensing and curing inflammations in blood vessels </div>



<h3>Example 2 molecular fuel supply</h3>

Focusing on the chain-reaction, Lipo-Hanabi can be applied to long-lasting batteries for molecular engines. If fuel for the molecular engines (such as ATP) is packed inside the liposome, they can constantly supply fuels to the molecular motor by a specific external signal. This kind of fuel supply system will be very useful to realize self-sustained molecular robots in the future.<br>

<div align="center"> <img src="http://openwetware.org/images/6/6a/Molecular-engineklug.png" width="95%" ><br> Fig. 2 Molecular fuel supply system</div> 

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