Biomod2013 Sendai ver2.0
Background and Motivation
Living things have many different systems of signal transduction. We are interested in mechanisms for the systems. If we could create a similar system to them, it would be amazing. Particularly, we paid attention to a system of amplifying signals. This system seems to be relatively simple and we can apply it to a variety of fields. Therefore, we tried to create the system that could amplify even weak signals by molecular design.
Our project is like the following. First of all, there are a lot of containers as small as weak signals. Every container contains keys. One of the containers, an initiator, detects a weak signal and opens. The keys released from the initiator open neighborhood containers. A reaction triggers other reactions over and over. This chain-reaction can amplify weak signals. In addition, if we put payloads into each container with keys, we can also carry something like medicines. By using a stimulus, we can control when to release payloads.