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<h1>Abstract</h1>
<h1>Abstract</h1>
<p>Living organisms are sensitive to various time changes of things, and it contributes to our life to a pretty good extent. In view of bionanotechnology, such as DNA computing and the formation of DNA nanostructures, it is important to sense and control the order and timing of molecular reactions as well. In this project, we propose an output system of releasing DNA molecules in a certain order. Sequential processing is the core of our system: our product inputs a DNA strand and then outputs corresponding DNAs according to the information coded in the input. When the input strand is “x1- x2- x3”, for example, it returns the output of X1, X2, and X3 DNA with this order by the reaction with molecules in a solution. We are investigating this system through simulations and experiments.
<p>In our project, we propose a programmable system which releases variable molecules in order. The core of this system is that the order of releasing outputs is written only on an input molecule. In this system, outputs are released repeatedly by using a set of molecules independent of the input. Since the length of the input is not limited, arbitrary number of releasing is possible. This property guarantees scalability in the system.  
If the output DNA is paired with a liposome and able to make it release its payloads, the system is expected to achieve the ordered molecule releasing system from liposomes. If we set medicine as the payload, this system can be applied to Drug Delivery System. However, here we propose entertainments that give us more delightful senses:  “World Taste Travel”. That is, by replacing the payload to taste component, we can taste various “cuisines” all over the world, automatically changing one by one.</p>
This system that possesses both programmability and scalability is realized by a cascade reaction of DNA, which is available for input and output molecule. The output DNAs released in order are converted into liposomes, which is used as a container of various kinds of molecule as payloads. Although Drug Delivery System is one possible application of this system by containing medicines in the liposomes, we rather focus on encapsulating taste substances to show the enjoyable feature of the system. </p>
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Revision as of 04:23, 29 August 2014

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<div id="homebutton" class="home"> <li id="stamp"><a href="http://openwetware.org/wiki/Biomod/2014/Sendai">Home</a></li> </div> <div id="globalnav" class="home"> <ul> <li id="gn-home"><a href="/wiki/Biomod/2014/Sendai">Home</a></li> <li id="gn-intro"><a href="/wiki/Biomod/2014/Sendai/Introduction">Introduction</a></li> <li id="gn-design"><a href="/wiki/Biomod/2014/Sendai/Design">Design</a></li> <li id="gn-simu"><a href="/wiki/Biomod/2014/Sendai/Simulation">Simulation</a></li> <li id="gn-xp"><a href="/wiki/Biomod/2014/Sendai/Experiment">Experiment</a></li> <!--<li id="gn-protocol"><a href="/wiki/Biomod/2014/Sendai/Protocol">Protocol</a></li>--> <li id="gn-dis"><a href="/wiki/Biomod/2014/Sendai/Discussion">Discussion</a></li> <li id="gn-team"><a href="/wiki/Biomod/2014/Sendai/Team">Team</a></li> <li id="gn-end"><a href="#"></a></li> </ul> </div> 

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<h1>Abstract</h1> <p>In our project, we propose a programmable system which releases variable molecules in order. The core of this system is that the order of releasing outputs is written only on an input molecule. In this system, outputs are released repeatedly by using a set of molecules independent of the input. Since the length of the input is not limited, arbitrary number of releasing is possible. This property guarantees scalability in the system. This system that possesses both programmability and scalability is realized by a cascade reaction of DNA, which is available for input and output molecule. The output DNAs released in order are converted into liposomes, which is used as a container of various kinds of molecule as payloads. Although Drug Delivery System is one possible application of this system by containing medicines in the liposomes, we rather focus on encapsulating taste substances to show the enjoyable feature of the system. </p> </div> 

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(C)Copyright Biomod 2014 Team Sendai<br /> E-MAIL: <a href="mailto:teamsendai2014@gmail.com"><span style="color:white">teamsendai2014@gmail.com</span></a> 

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