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<h1>Background＆Motivation</h1>
<h1>Background</h1>
<p>We recognize everything through sensory organs in our lives. Time change is important for our sensory organs when they recognize information. In the process of DNA nanostructure formation, order of change, timing, and time change of concentration are very important factors. Existing DNA devices such as logic gates focus on input and output. And, DNA structures such as Oscillator can control output concentration precisely. However, there is a problem that it is hard to get different output about.</p>
<img src="http://openwetware.org/images/6/60/Gomi_03.png">
<h1>Motivation</h1>
<p>Therefore, in this study, we designed a system which can effuse several DNA molecules at regular intervals in order to control time and order of DNA reactions. In this system, variable molecules can be effused by adapting output DNA to liposome-modified DNA.
This system is consisted of a group of biomolecules including DNA, and has high biocompatibility. So we hope that we apply this system to DDS (Drug Delivery System) by effusing variable medicines contained in liposomes to the affected part at regular intervals. However, we pursued the entertainment property appealing to our sense. That is, we designed “Taste Virtual Reality System”, which stimulate taste bud, and present taste substance.</p>


DNAナノ構造形成プロセスの構築では，DNAの反応の順番やタイミングが重要な要素である．現在，DNAの濃度の時間変化を作り出す機構を実現するために，オシレーターなどの手法が提案されている．しかし，現在のところ，DNAナノ構造の形成プロセス中の反応の順番や濃度の時間変化を調整するデバイスは開発されていない．それらを調整することができれば，プロセス中のウェイストや予期せぬ反応の発生を抑制することができる．このことによって，たとえば，複雑な形成プロセスを持つナノ構造を作り出すことが今よりも簡単になることが期待される．
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Revision as of 20:35, 22 August 2014

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<body> <div id="globalnav"> <ul> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821">Home</a></li> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821/Introduction">Introduction</a></li> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821/Design">Design</a></li> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821/Simulation">Simulation</a></li> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821/Experiment">Experiment</a></li> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821/Protocol">Protocol</a></li> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821/Discussion">Discussion</a></li> <li><a href="/wiki/Biomod/2014/Sendai/temp/0821/Team">Team</a></li> </ul> </div> <div id="main"> <h1>Background</h1> <p>We recognize everything through sensory organs in our lives. Time change is important for our sensory organs when they recognize information. In the process of DNA nanostructure formation, order of change, timing, and time change of concentration are very important factors. Existing DNA devices such as logic gates focus on input and output. And, DNA structures such as Oscillator can control output concentration precisely. However, there is a problem that it is hard to get different output about.</p> <img src="http://openwetware.org/images/6/60/Gomi_03.png"> <h1>Motivation</h1> <p>Therefore, in this study, we designed a system which can effuse several DNA molecules at regular intervals in order to control time and order of DNA reactions. In this system, variable molecules can be effused by adapting output DNA to liposome-modified DNA. This system is consisted of a group of biomolecules including DNA, and has high biocompatibility. So we hope that we apply this system to DDS (Drug Delivery System) by effusing variable medicines contained in liposomes to the affected part at regular intervals. However, we pursued the entertainment property appealing to our sense. That is, we designed “Taste Virtual Reality System”, which stimulate taste bud, and present taste substance.</p>

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