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&nbsp; Fig. 7a and 7b shows the photograph and the SEM image of the amino-functionalized mesoporous silica (MPS-NH2) particle. <br>Spherical particles with the diameter of about 300 nm to 1000 nm are observed. However, because the size of the mesopores is too small, assumed as 2 nm, we could not observed the pores. After the modification with -COOH group (Fig. 7c) and with DNA (Fig. 7d), there were no significant changes in SEM. Therefore, it is understood that the shape of former particle is maintained. <br>
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Revision as of 10:36, 25 October 2014

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<a name="header"></a> <img src="/images/4/46/Fitaologo.PNG" alt" alt="" width="422" height="98" hspace="0" align="left">



  • <a href="http://openwetware.org/wiki/Biomod/2014/Fukuoka#home">Home</a>
  • <a href="fit_Introduction.html#pro">Projects</a>
    • <a href="fit_Introduction.html#back">background & Motivation</a>
    • <a href="fit_Introduction.html#goal">Goals</a>
  • <a href="fit_Approach and Goals.html#des">Design</a>
    • <a href="fit_Approach and Goals.html#ear">Early Design</a>
    • <a href="fit_Approach and Goals.html#fin">Final Design</a>
  • <a href="fit_Method.html#met">Method</a>
    • <a href="#a">Barrel particle</a>
    • <a href="#b">DNA modified</a>
    • <a href="#c">樽と人形の結合</a>
      • 　　　
    • <a href="#d">樽人形剣</a>
      • 　　　
    • <a href="#e">Material</a>
  • <a href="fit_Results and Discussion.html#">Result and Discasstions</a>
    • <a href="#a">Barrel particle and Doll particle</a>
    • <a href="#b">DNA modified</a>
    • <a href="#c">樽と人形の結合</a>
    • <a href="#d">樽人形剣</a>
      • 　　　
    • <a href="#e">Conclusion</a>
  • <a href="fit_Member.html#team">Team</a>
    • <a href="fit_Member.html#men">Menber</a>
    • <a href="fit_Member.html#spo">Sponsor</a>


<a name="a"></a>

barrel

  Fig. 7a and 7b shows the photograph and the SEM image of the amino-functionalized mesoporous silica (MPS-NH2) particle.
Spherical particles with the diameter of about 300 nm to 1000 nm are observed. However, because the size of the mesopores is too small, assumed as 2 nm, we could not observed the pores. After the modification with -COOH group (Fig. 7c) and with DNA (Fig. 7d), there were no significant changes in SEM. Therefore, it is understood that the shape of former particle is maintained.
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  We create “nano Pop-up Pirate “using by the complementary DNA base-pairing. Pop-up Pirate is a famous Japanese toy. A doll is sitting on the Barrel. Players stab the sword to when player stabs to the specific point, the doll will fly away from a barrel.
　Fluorescence labeled DNA was bound to the porous silica particle, of the barrel. And different fluorescence labeled mismatched DNA who is a doll in bound to the Barrel DNA. When mismatched DNA that is a sward in added, mismatched DNA would be released.
　Two fluorescence reagents are constructed the FRET system, and used in the detection of the states of DNAs. This system is applicable for the Drug Delivery systems .A porous silica is a container .DNA system is a drug release regulation. Free system is a drug release detection.

<a name="b"></a> goal

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<a name="c"></a> Abstract <a name="d"></a>

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Abstract

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<a name="e"></a> Abstract

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<img alt="" src="/images/0/0b/Fitfisilica.png" width="350" height="350" border="0" />

figure1

 <img alt="" src="/images/4/4c/Fitkspec.png" width="350" height="350" border="0" />

figure2
<img alt="" src="/images/1/16/FitsilicaT.png" width="250" height="250" border="0" />

figure3-1
<img alt="" src="/images/4/48/FitsilicaF.png" width="250" height="250" border="0" />

figure3-2
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figure3-3
<a href="#header"><img src="（画像）" /></a>

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