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Cover Page Articles

2007

Journal Articles

1. Ryan Cooper and Luke P. Lee, "Chips & Tips: Preventing suspension settling during injection," Lab on a Chip, Chips & Tips. online article
2. Liz Y. Wu, Dino Di Carlo, Luke P. Lee, "Microfluidic self-assembly of tumor spheroids for anticancer drug discovery ," Biomedical Microdevices (2007). online article
3. J. Tanner Nevill, Ryan Cooper, Megan Dueck, David N. Breslauer and Luke P. Lee, "Integrated microfluidic cell culture and lysis on a chip," Lab on a Chip, DOI: 10.1039/b711874k. advance online article
4. J. Noh, S.H. Kim, L.P. Lee, S.I. Woo, "One-step synthesis and characterization of single Au microballs through self-organization," Materials Letters 61(16), 3334-3337 (2007). online article
5. Mimi Y. Zhang, Philip J. Lee, Paul J. Hung, Terry Johnson, Luke P. Lee, Mohammed R. K. Mofrad, "Microfluidic environment for high density hepatocyte culture," Biomedical Microdevices (2007). online article
6. Gang L. Liu, Yazmin T. Rosa-Bauza, Cleo M. Salisbury, Charles Craik, Jonathan A. Ellman, Fanqing Frank Chen, Luke P. Lee, "Peptide-Nanoparticle Hybrid SERS Probes for Optical Detection of Protease Activity," Journal of Nanoscience and Nanotechnology, 7(7), 2323-2330 (2007). online article
7. Philip J. Lee, Paul J. Hung, and Luke P. Lee, "An Artificial Liver Sinusoid with a Microfluidic Endothelial-like Barrier for Primary Hepatocyte Culture," Biotechnology and Bioengineering (2007). advance online article (selected as cover page article)
8. Michelle Khine, Cristian Ionescu-Zanetti, Andrew Blatz, Lee-Ping Wang and Luke P. Lee, "Single-cell electroporation arrays with real-time monitoring and feedback control," Lab Chip (2007). advance online article

2006

Journal Articles

1. Philip J. Lee, Paul J. Hung, Vivek M. Rao, and Luke P. Lee, "Nanoliter scale microbioreactor array for quantitative cell biology," Biotechnology and Bioengineering, 94, pp 5-14 (2006). pdf
2. Jeonggi Seo, and Luke P. Lee, "Effects on wettability by surfactant accumulation/depletion in bulk polydimethylsiloxane (PDMS)," Sensors and Actuators B, 119(1), 192-198 (2006). online article
3. Soo Ho Kim, Jermim Noh, Min Ku Jeon, Ki Woong Kim, Luke P. Lee, and Seong Ihl Woo, "Micro-Raman thermometry for measuring the temperature distribution inside the microchannel of a polymerase chain reaction chip," Journal of Micromechanics and Microengineering, 16(3), 526-530 (2006). online article
4. Gang L. Liu, Jaeyoun Kim, Yu Lu, and Luke P. Lee, "Fluorescence enhancement of quantum dots enclosed in Au nanopockets with subwavelength aperture," Applied Physics Letters 89, 241118 (2006) (selected for the December 25, 2006 issue of Virtual Journal of Nanoscale Science & Technology.) online article
5. Jaeyoun Kim, Gang L. Liu, Yu Lu, and Luke P. Lee, "Spectral tuning of localised surface plasmon-polariton resonance in metallic nano-crescents," IEE Proc Nanobiotechnol, 153(3), 42-6 (2006.) online article
6. Dino Di Carlo, and Luke P. Lee, "Dynamic Single-Cell Analysis for Quantitative Biology," Anal Chem, 78, 7918-7925 (2006) (selected as cover page article.) online article
7. Gang L. Liu, Yadong Yin, Siri Kunchakarra, Bipasha Mukherjee, Daniele Gerion, Stephen D. Jett, David G. Bear, Joe W. Gray, A. Paul Alivisatos, Luke P. Lee, and Fanqing Frank Chen, "A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting," Nature Nanotechnology, 1, 47-52 (2006). pdf
8. Adrian Y. Lau, Paul J. Hung, Angela R. Wu, and Luke P. Lee, "Open-access microfluidic patch-clamp array with raised lateral cell trapping sites," Lab Chip, 6, 1510 (2006) (selected as cover page article, selected as hot article, and selected for issue 22 of the RSC Chemical Biology Virtual Journal). pdf
9. Dino Di Carlo, Liz Y. Wu, Luke P. Lee, "Dynamic single cell culture array," Lab Chip, 6, 1445-1449 (2006). pdf
10. Ki-Hun Jeong, Jaeyoun Kim, and Luke P. Lee, "Biologically inspired artificial compound eyes," Science, 312, p. 557-561 (2006). pdf
11. Dino Di Carlo, Nima Aghdam, Luke P. Lee, "Single-cell enzyme concentrations, kinetics, and inhibition analysis using high density hydrodynamic cell isolation arrays," Analytical Chemistry 78(14), 4925-4930 (2006). pdf
12. Poorya Sabounchi, Cristian Ionescu-Zanetti, Roger Chen, Manijiree Karandikar, Jeonggi Seo, and Luke P. Lee, "Soft-state biomicrofluidic pulse generator for single cell analysis" Applied Physics Letters 88, 183901 (2006). pdf
13. Philip J. Lee, Rob Lin, James Moon, and Luke P. Lee, "Microfluidic alignment of collagen fibers for in vitro cell cultures," Biomed Microdevices, 8, 35-41 (2006). pdf
14. David N. Breslauer, Philip J. Lee, and Luke P. Lee, "Microfluidics-Based Systems Biology," Molecular BioSystems, 2, 97-112 (2006). pdf
15. Gang L. Liu, Jaeyoun Kim, Yu Lu and Luke P. Lee, "Optofluidic Control via Photothermal Nanoparticles," Nature Materials 5(1), 27-32 (2006). pdf
16. Cristian Ionescu-Zanetti, J. Tanner Nevill, Dino Di Carlo, Ki-Hun Jeong, and Luke P. Lee, "Nanogap Capacitors: Sensitivity to Sample Permittivity Changes," Journal of Applied Physics, 99, 024305 (2006). pdf

Proceedings

1. D. Malleo, D. Di Carlo, J. T. Nevill, D. Holmes, L. P. Lee, H. Morgan, "Single Cell Differential Impedance Spectroscopy Analysis Using High Density Hydrodynamic Cell Trapping Arrays", Proceedings of Micro Total Analysis Systems 2006, pp.1292-1294, Tokyo, Japan, November 5-9, 2006.
2. D.N. Breslauer, S.J. Muller, L. P. Lee, "Biologically-Inspired Fiber Spinning." BMES, Chicago, USA, October 11-14, 2006.
3. Di Carlo D, Wu LW, Lee LP. Dynamic Single Cell Culture Array. In: MicroTAS 2006. Proceedings of the 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences; 2006 Nov 5-9; Tokyo, Japan; 2006.
4. Wu LW, Di Carlo D, Lee LP. Microfluidic Self-assembly of Tumor Spheroids for Studies of Anticancer Drug Actions and Interactions. In: MicroTAS 2006. Proceedings of the 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences; 2006 Nov 5-9; Tokyo, Japan; 2006.
5. J.T. Nevill, D. Di Carlo, and L.P. Lee, "Nanocavity Network-Based Impedance Sensor for Molecular Diagnostics," Proceedings of Micro Total Analysis Systems 2006, pp. 1283-1285, Tokyo, Japan, November 5-9, 2006.
6. Di Carlo D, Shaw J, Lee LP. Dynamic Studies of Pore-Forming Toxins Using a Microfluidic Cell Array. In: MicroTAS 2006. Proceedings of the 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences; 2006 Nov 5-9; Tokyo, Japan; 2006.
7. Zhang MY, Di Carlo D, Wu LY, Lee SM, Lee LP. High-Density Spheroid Arrays for 3-D Liver Cell Culture and Secretion Analysis. In: MicroTAS 2006. Proceedings of the 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences; 2006 Nov 5-9; Tokyo, Japan; 2006.
8. P. Sabounchi, C. Ionescu-Zanetti, N. Ghorashian, and L. P. Lee, "Soft-State Biomicrofluidic Pulse Generator For Fast Endocytic Recycling Analysis of Single Cells," Proceedings of Micro Total Analsysis Systems 2006, pp. 990-992, Tokyo, Japan, November 5-9, 2006
9. N. Ghorashian, P. Goodwill, P. Sabounchi, L. P. Lee, "Fast Biological Microfluidic Pulse Generator for Single Cell Electrophysiology." BMES, Chicago, USA, October 11-14, 2006.
10. Hansang Cho, Yi-Tao Long, and Luke P. Lee, “Study on Biomolecules by Electrokinetic Concentration-based SERS Amplification”, Biophysical Society's 51st Annual Meeting, Baltimore, Maryland, USA, March 3-7, 2007
11. Hansang Cho and Luke P. Lee, “A novel integrated microfluidic SERS-CD with high-throughput centrifugal cell trapping array for quantitative biomedicine," 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (μTAS2006), pp. 642-644, Tokyo, Japan, Nov. 5 - 9, 2006
12. Hansang Cho, Jeonggi Seo, Luke P. Lee, "A novel integrated centrifugal cell trapping SERS-CD platform for quantitative cell analysis", the Biomedical Engineering Society Annual Meeting, (BMES2006) in Chicago, USA, Oct. 11-14, 2006
13. Hansang Cho, Beomseok Kim, and Luke P. Lee, “Tunable surface-enhanced Raman scattering probes for single biomolecular detections”, Biophysical Society's 50th Annual Meeting, Salt Lake City, Utah, USA, February 18-22, 2006
14. E.S.Lee, G.L.Liu and L.P.Lee, "Localized optically-activated gene release in breast cancer cells using Au nanoparticles as carriers," Biomedical Engineering Society (BMES), Chicago, IL, USA, October 11-14, 2006
15. E.S.Lee, G.L.Liu, F.J.Kim, L.P.Lee, "Localized optical activation of therapeutic gene release in breast cancer cells using photothermal nanocrescents as oligonucleotide carriers," Micro Total Analysis Systems (uTAS), Tokyo, Japan, November 5-9, 2006, p.284-286
16. M. Y. Zhang, D. Di Carlo, L. Y. Wu, and L. P. Lee. "High Density Spheroid Arrays for 3-D Liver Cell Culture and Secretion Analysis." Proceedings of the 10th International Conference on Micro Total Analysis Systems, Tokyo, Japan, Nov. 5-9, 2006.
17. M. Y. Zhang, D. Di Carlo, L. Y. Wu, S. M. Lee, P. F. White, M. R.K. Mofrad, and L. P. Lee. "Self Assembly of Hepatocyte Spheroids on a Chip." Proceedings of the 2006 Biomedical Engineering Society Conference, Chicago, IL, Oct. 11-14, 2006.
18. P. F. White, S. Lee, M. Y. Zhang, D. Liepmann, L. P. Lee, and M. R.K. Mofrad. "Microfluidic Stresses in a Cell Trapping Array for 3-D Liver Cell Culture." Proceedings of the 2006 Biomedical Engineering Society Conference , Chicago, IL, Oct. 11-14, 2006.

2005

Journal Articles

1. Jermim Noha, Su Whan Sunga, Min Ku Jeona, Soo Ho Kima, Luke P. Lee, and Seong Ihl Woo, "In situ thermal diagnostics of the micro-PCR system using liquid crystals," Sensors and Actuators A, 122(2), 196-202 (2005). online article
2. Luke P. Lee and Robert Szema, “Inspirations from Biological Optics for Advanced Photonic Systems,” Science, vol. 310, no. 5751, 1148 – 1150 (2005) (selected as cover page article). pdf
3. Philip J. Lee, Paul J. Hung, Robin Shaw, Lily Jan, and Luke P. Lee, "Microfluidic Application-Specific Integrated Device for Monitoring Direct Cell-Cell Communication via Gap Junctions Between Individual Cell Pairs," Appl. Phys. Lett. 86, 223902 (2005) (selected as cover page article of APL, and selected for the June 1, 2005 issue of Virtual Journal of Biological Physics Research and for the June 6, 2005 issue of Virtual Journal of Nanoscale Science & Technology). pdf
4. Paul Hung, Philip Lee, and Luke P. Lee, "A Continuous Perfusion Microfluidic Cell Culture Array for High Throughput Cell-based Assays," Biotechnology & Bioengineering, 89, 1-8 (2005) (selected as cover page article and one of Top Seven Cell-Based HTS Assays Articles from CHI 2006). pdf
5. James J. Moon, Melissa Matsumoto, Shyam Patel, Luke Lee, Jun-Lin Guan, and Song Li, "Role of Cell Surface Heparan Sulfate Proteoglycans in Endothelial Cell Migration and Mechanotransduction," Journal of Cellular Physiology, 203 (1): 166-176 APR (2005) (selected as cover page article). pdf
6. Michelle Khine, Adrian Lau, Cristian Ionescu-Zanetti, Jeonggi Seo, and Luke P. Lee, "A Single Cell Electroporation Chip," Lab on a Chip, 5 (1), 38-43 (2005) (selected as hot article). pdf
7. Dino Di Carlo, Cristian Ionescu-Zanetti, Yolanda Zhang, Paul Hung and Luke P. Lee, "On-Chip Cell Lysis by Local Hydroxide Generation," Lab on a Chip 5 (1) (2005) (selected as hot article). pdf
8. Paul J. Hung, Philip J. Lee, Poorya Sabounchi, Nima Aghdam, Robert Lin, and Luke P. Lee, "A Novel High Aspect Ratio Microfluidic Design to Provide a Stable and Uniform Microenvironment for Cell Growth in High Throughput Mammalian Cell Culture Chip Array," Lab on a Chip, 5 (1), 44-48 (2005) (selected as hot article). pdf
9. Wesley C. Chang, Luke P. Lee and Dorian Liepmann, "Biomimetic Technique for Adhesion-based Collection and Separation of Cells in a Microfluidic Channel," Lab on a Chip, 5 (1), 64-73 (2005) (selected as hot article). pdf
10. Jaeyoun Kim, Gang L. Liu, Yu Lu and Luke P. Lee, "Intra-Particle Plasmonic Coupling of Tip and Cavity Resonance Modes in Metallic Apertured Nanocavities," Optics Express 13, 8332-8338 (2005). pdf
11. Gang L. Liu, Yu Lu, Jaeyoun Kim, Joey C. Doll and Luke P. Lee, "Magnetic Nanocrescents as Controllable Surface Enhanced Raman Scattering Nanoprobes for Biomolecular Imaging," Advanced Materials, 17, 2683-2688 (2005). pdf
12. Gang L. Liu and Luke P. Lee, "Nanowell surface enhanced Raman scattering arrays fabricated by soft-lithography for label-free biomolecular detections in integrated microfluidics," Applied Physics Letters 87, 074101 (2005). pdf
13. Gang L. Liu, Joey C. Doll and Luke P. Lee, "High-speed multispectral imaging of nanoplasmonic array," Optics Express 13, 8520-8525 (2005). pdf
14. Gang L. Liu, Victoria B. Rodriguez, and Luke P. Lee, "Time-Resolved Optical Sensing of Oligonucleotide Hybridization via Au Colloidal Nanoparticles," Journal of Nanoscience and Nanotechnology, 5, 1933-1937 (2005)
15. Cristian Ionescu-Zanetti, Robin M. Shaw, Jeonggi Seo, Yuh-Nung Jan, Lily Y. Jan, and Luke P. Lee, "Mammalian Electrophysiology on a Microfluidic Platform," Proc. Natl. Acad. Sci. USA, 102(26), 9112-9117 (2005). pdf
16. Jaeyoun Kim, Gang L. Liu, and Luke P. Lee, "Lens-scanning Raman microspectroscopy system using compact disc optical pickup technology," Opt. Express 13, 4780-4785 (2005). pdf
17. Ki-Hun Jeong, Chris G. Keller, and Luke P. Lee, "Direct Force Measurements of Biomolecular Interactions by Nanomechanical Force Gauge," Appl. Phys. Lett. 86, 193901 (2005) (selected for the May 16, 2005 issue of Virtual Journal of Nanoscale Science & Technology and for the May 15, 2005 issue of Virtual Journal of Biological Physics Research). pdf
18. Yu Lu, Gang L. Liu, Jay Kim, Yara X. Mejia, and Luke P. Lee, "Nanophotonic Crescent Moon Structures with Sharp Edge for Ultrasensitive Biomolecular Detections by Local Electromagnetic Field Enhancement Effect," Nano Letters, 5(1), 119-124 (2005). pdf
19. Yu Lu, Gang L. Liu, and Luke P. Lee, "High Density Silver Nanoparticle Film with Temperature-Controllable Interparticle Spacing for a Tunable Surface Enhanced Raman Scattering Substrate," Nano Letters, 5(1), 5-9, (2005). pdf
20. Ming Yi, KiHun Jeong, and Luke P. Lee, "'Theoretical and Experimental Study towards a Nanogap Dielectric Biosensor," Biosensor and Bioelectronics, 20, 1320-1326 (2005). pdf
21. Ki-Hun Jeong and Luke P. Lee, "A Self-Aligned Vertical Comb Drive Microfabricated on a Single SOI Wafer for Optical MEMS Applications," Journal of Micromechanics and Microengineering,15, 1-5 (2005).
22. Jaeyoun Kim, Ki-Hun Jeong, Luke P. Lee, "Artificial Ommatidia by Self-aligned Microlenses and Waveguides," Optics Letters, Vol. 30 (1), 5-7 (2005). pdf
23. Cristian Ionescu-Zanetti, Lee-Ping Wang, Dino Di Carlo, Paul Hung, Andrea Di Blas, Richard Hughey, and Luke P. Lee, "Alkaline Hemolysis Fragility is Dependent on Cell Shape: Results From a Morphology Tracker," Cytometry Part A, Vol. 65A (2), 116-123 (2005). pdf
24. N. Chronis and L. P. Lee, "Electrothermally Activated SU-8 Microgripper for Single Cell Manipulation in Solution," Journal of Microelectromechanical Systems 14(4), 857-863 (2005). pdf

Proceedings

1. Gang L. Liu, Erik H. Anderson, James A. Liddle, and Luke P. Lee, "Plasmonic Nanorainbow for Label-Free Biomolecule Sensing," Proc. SPIE Int. Soc. Opt. Eng. 5703, 91 (2005).
2. Gang L. Liu and Luke P. Lee, "Optical Sensing of Electrochemical Reactions on a Bio-hybrid Nanoparticle," Proc. SPIE Int. Soc. Opt. Eng. 5705, 123 (2005).
3. J. Tanner Nevill, Ki-Hun Jeong, and Luke P. Lee, "Ultrasensitive Nanogap Biosensor to Detect Changes in Structure of Water and Ice," Proc. Transducers, Seoul, Korea, p. 1577-1580, June 5-9, 2005.
4. J. Tanner Nevill, Dino Di Carlo, Peng Liu, Ki-Hun Jeong, and Luke P. Lee, "Detection of Protein Conformational Changes with a Nanogap Biosensor," Proc. Transducers, Seoul, Korea, p. 1668-1671, June 5-9, 2005.
5. K. Jeong, J. Kim, L.P. Lee, Polymeric Synthesis of Biomimetic Artificial Compound Eyes, Proc. Transducers, Seoul, Korea, p. 1110-1114, June 5-9, 2005

2004

Journal Articles

1. Paul J. Hung, Ki-Hun Jeong, Gang L. Liu, and Luke P. Lee, "Suspensions for Electrical Connections on the Tunable Elastomer Membrane," Appl. Phys. Lett., Vol. 85, No. 24, 6051-6053 (2004). pdf
2. S. Kwon and L. P. Lee, "Micromachined Transmissive Scanning Confocal Microscope," Optics Letter, Vol. 29, No. 7, 706-708 (2004). pdf
3. V. Milanovic, S. Kwon, and L. P. Lee, "High Aspect Ratio Micromirrors with Large Static Rotation and Piston Actuation for Photonic Microsystems," IEEE Photonics Technology Letter, Vol. 16, No. 8, 1891-1893, (2004).
4. J. Seo, C. Ionescu-Zanetti, J. Diamond, R. Lal, and L. P. Lee, "Integrated Multiple Patch-clamp Array Chip via Lateral Cell Trapping Junctions," Appl. Phys. Lett., Vol. 84, No. 11, 1973-75 (2004). pdf
5. N. Chronis and L. P. Lee, "Total Internal Reflection-based Biochip Utilizing a Polymer-filled Cavity with a Micromirror Sidewall," Lab on a Chip, 4 (2), 125-130 (2004). pdf
6. K. Jeong, G. L. Liu, N. Chronis, and L. P. Lee, "Tunable Microdoublet Lens Array," Optics Express 12, 2494-2500 (2004). pdf
7. R. M. Lorenz, C. L. Kuyper, P. B. Allen, L. P. Lee, D. T. Chiu, "Direct Laser Writing on Electrolessly Deposited Thin Metal Films for Applications in Micro- and Nanofluidics," Langmuir, 20(5); 1833-1837 (2004). pdf
8. R. Szema, J. Rastegar, L. P. Lee, "An Artificial Compound Eye for Stereoendoscopy," Journal of Medical Engineering and Technology, Vol. 28, No. 3, 117 - 124, May-June (2004).
9. J. Seo and L. P. Lee, "Disposable Integrated Microfluidics with Self-aligned Planar Microlenses," Sensors & Actuators B-Chemical, 99, 615-622 (2004).
10. S. Kwon, V. Milanovic, and L. P. Lee, "Vertical Combdrive based 2D Gimbaled Micromirrors with Large Static Rotation by Backside Island Isolation," IEEE Journal of Selective Topics in Quantum Electronics, Vol. 10, No. 3 (2004).
11. A. Chediak, Z. S. Luo, J. Seo, N. Cheung, L. P. Lee, and T. D. Sands, "Heterogeneous Integration of CdS Filters with GaN LEDs for Fluorescence Detection Microsystems," Sensors & Actuators A-Physical, 111 (1): 1-7 (2004).
12. Narayan Sundararajan, Michael S. Pio, Luke P. Lee, and Andrew A. Berlin, "Three-Dimensional Hydrodynamic Focusing in Polydimethylsiloxane Micro-Channels for Molecular Detection," Journal of Microelectromechanical Systems, Vol. 13 (4), 559 -567 (2004).

Proceedings

1. N. Chronis and L. P. Lee, "Polymer Mems-based Microgripper for Single Cell Manipulation," Proceedings of IEEE MEMS 2004, pp. 17-20, Jan. 25-29, 2004. pdf
2. K. Jeong; G. L. Liu, N. Chronis, and L. P. Lee, "Tunable Microdoublet Lens Array," Proceedings of IEEE MEMS 2004, pp. 37-40, Jan. 25-29, 2004. pdf
3. Dino Di Carlo, Cristian Ionescu-Zanetti, Yolanda Zhang, Paul Hung and Luke P. Lee, "On-Chip Cell Lysis by Local Hydroxide Generation," Proceedings of Micro Total Analysis Systems 2004, pp. 165-167, Malmo, Sweden, September 26-30, 2004.
4. Cristian Ionescu-Zanetti, Jeonggi Seo, and Luke P. Lee, "Electrophysiology using a High-density Microfluidic Array for High-throughput Patch Clamp Measurements," Proceedings of Micro Total Analysis Systems 2004, pp. 177-179, Malmo, Sweden, September 26-30, 2004.
5. Nicholas Chronis and Luke P. Lee, "A Polymer-based Microrobotic Workstation for Single Cell Manipulation," Proceedings of Micro Total Analysis Systems 2004, pp. 407-409, Malmo, Sweden, September 26-30, 2004.

2003

Journal Articles

1. D. Di Carlo , K. Jeong and L. P. Lee, "Reagentless Mechanical Cell Lysis by Nanoscale Barbs in Microchannels for Sample Preparation," Lab on a Chip, Vol. 3, 287-291 (2003) (Selected as Hot Article). pdf
2. C. Ionescu-Zanetti, K. Cheung, R. Lal, and L. P. Lee, "Simultaneous Imaging of Ionic Conductivity and Morphology of a Microfluidic System," Journal of Applied Physics, 93 (12), 10134-10136 (2003).
3. K. Cheung, K. Djupsund, Y. Dan, and L. P. Lee, "Implantable Multichannel Electrode Array Based on SOI technology," Journal of Microelectromechanical Systems, Vol. 12 (2), 179 -184 (2003).
4. N. Chronis, G. L. Liu, K. Jeong, and L. P. Lee, "Tunable Liquid-filled Microlens Array Integrated with Microfluidic Network," Optics Express, Vol. 11, No.19, 2370-2378 (2003). pdf
5. Selena Chan, Sunghoon Kwon, Tae-Woong Koo, Luke P. Lee, and Andrew A. Berlin, "Surface-Enhanced Raman Scattering of Small Molecules from Silver Coated Silicon Nanopores," Adv. Mater. 15, No. 19, 1595-1598 (2003).
6. Y. Choi, J. Lee, J. Zhu , G. A. Somorjai, L. P. Lee, and J. Bokor, "Sublithographic nanofabrication technology for nanocatalysts and DNA chips," Journal of Vacuum Science & Technology B, 21 (6): 2951-2955 (2003).

Proceedings

1. Y. Choi, J. Lee, J. Zhu , G. A. Somorjai, L. P. Lee, and J. Bokor, "Sub-lithographic patterning technology for nanowire model catalysts and DNA label-free hybridization detection," Proc. SPIE Int. Soc. Opt. Eng. 5220, 10 (2003).
2. S. Oh, J.S. Lee, K. Jeong, and L. P. Lee, "Minimization of Electrode Polarization Effect by Nanogap Electrodes for biosensor Applications," IEEE MEMS 2003, pp. 52-55; Kyoto, Japan, Jan. 19-23, 2003.
3. J. A. Chediak, Z. Luo, J. Seo, N. Cheung, L. P. Lee, T. Sands, "Hybrid Integration of CdS Filters with GaN LEDs for Biophotonic Chips," IEEE MEMS 2003, pp. 323-326; Kyoto, Japan, Jan. 19-23, 2003.
4. M. Khine, J. K. Thompson, S. M. Bierer, L. J. Altamirano, R. D. Freeman, and L. P. Lee, "A Combined Neural-oxygen Sensing Multi-channel Electrode Array," Proceedings of IEEE Neural Engineering 2003, pp. 204-207, 20-22 March, 2003.
5. S. Kwon, G. L. Liu, K. Jeong, and L. P. Lee, "Micro Confocal Line Scanning System for High Density Microfluidics," Optical MEMS, 2003, pp. 10-11, IEEE/LEOS International Conference, 18-21 Aug. 2003.
6. G. L. Liu, Y. Choi, and L. P. Lee, "Configurable 3D Nanoscale High Aspect Ratio Pillars for Surface-Enhanced Raman Spectroscopy," IEEE Nanotechnology 2003, pp. 425-427, 12-14 Aug. 2003.
7. D. Di Carlo, H. Kang; X. Zeng, K. Jeong, and L. P. Lee, "Nanogap-based Dielectric Immunosensing," TRANSDUCERS 2003, Solid-State Sensors, Actuators and Microsystems, pp. 1180 - 1183, 2003.
8. J. Seo and L. P. Lee, "Fluorescence Amplification by Self-aligned Integrated Microfluidic Optical Systems," TRANSDUCERS 2003, Solid-State Sensors, Actuators and Microsystems, pp. 1136 - 1139, 2003.
9. K. Jeong, L. P. Lee, "A Novel Fabrication Method of a Vertical Comb Drive using a Single SOI Wafer for Optical MEMS Applications," Transducers 2003, Solid-State Sensors, Actuators and Microsystems, pp. 1462 - 1465, 2003.
10. H. Kang, J. Seo, D. Di Carlo, Y. Choi, and L. P. Lee, "Planar Nanogap Capacitor Arrays on Quartz for Optical and Dielectric Bioassays," Proceedings of Micro-Total Analysis Systems 2003, pp. 697-700, Squaw Valley, CA, USA, October 5-9, 2003.
11. G. L. Liu, Y. Choi, S. Kwon, and L. P. Lee, "Nanopillar Substrate for SERS," Proceedings of Micro-Total Analysis Systems 2003, pp. 705-708, Squaw Valley, CA, USA, October 5-9, 2003.
12. S. Kwon, G. L. Liu, K. Jeong, and L. P. Lee, "Micro Confocal Line Scanning System for Multiplexed Biochips, Proceedings of Micro-Total Analysis Systems 2003, pp. 1255-1258, Squaw Valley, CA, USA, October 5-9, 2003.
13. N. Chronis and L. P. Lee, "Total Internal Reflection-based Biochip for High Throughput Bioassays," Proceedings of Micro-Total Analysis Systems 2003, pp. 1323-1326, Squaw Valley, CA, USA, October 5-9, 2003.

2002

Journal Articles

1. S. Kwon, V. Milanovic, and L. P. Lee, "Large Displacement Vertical Microlens Scanner with Low Driving Voltage," IEEE Photonic Letter, 14 (11), 1527-1530 (2002). abstract

Proceedings

1. J. Seo and L. P. Lee, "Self-assembly Template by Surface Modified Micropatterned Photoresist," Proceedings of IEEE MEMS 2002, pp. 192-195, Las Vegas, NV, USA, January 2002.
2. S. Kwon and L. P. Lee, "Stacked Two-dimensional Micro-lens Scanner for Micro-confocal Imaging Array," Proceedings of IEEE MEMS 2002, pp. 483-486, Las Vegas, NV, USA, January 2002.
3. J. Lee, Y. Choi, M. Pio, J. Seo and L. P. Lee, "Nanogap Capacitors for Label Free DNA Analysis," Proceedings of Materials Research Society 2002 Spring Meeting, pp. 185-190, April 1-5, San Francisco, CA.
4. T. Kubow, K. Cheung, L. F. Bentley, and L. P. Lee, "Microfabricated Patch-clamp Array for Neural MEMS Applications," Proceedings of Materials Research Society 2002 Spring Meeting, pp. 197-202, April 1-5, San Francisco, CA.
5. M. S. Pio, S. Kwon, Y. Choi, and L. P. Lee, "Batch Fabrication of Nanopillars for Multiplexed Nanofluidic SERS Arrays," Proceedings of Materials Research Society 2002 Spring Meeting, pp. 179-184, April 1-5, San Francisco, CA.
6. K. C. Cheung, Y. Choi, T. Kubow, and L. P. Lee, "Nanostructured Electrodes for Improved Neural Recording," Proceedings of Materials Research Society 2002 Spring Meeting, pp. 191-196, April 1-5, San Francisco, CA.
7. W. C. Chang, L. P. Lee, D. Liepmann, "Adhesion-based cell separation in microdevices," Proceedings of Materials Research Society 2002 Spring Meeting, pp.155-160, April 1-5, San Francisco, CA.
8. K. Cheung, T. Kubow, and L. P. Lee, "Individually Addressable Planar Patch Clamp Array, IEEE-EMBS Proceedings on Microtechnologies in Medicine & Biology, pp.72-76, Madison, Wisconsin, USA, May 2-4, 2002.
9. W. Chung, D. Liepmann, and L. P. Lee, "A Biomimetic Method for Extracting Leukocytes from Blood in Microfluidic Devices," IEEE-EMBS Proceedings on Microtechnologies in Medicine & Biology, pp. 184-188, Madison, Wisconsin, USA, May 2-4, 2002.
10. P R. Gill and L. P. Lee, "MAPS: The Micro Action Potential Scanner," IEEE-EMBS Proceedings on Microtechnologies in Medicine & Biology, pp. 232-236, Madison, Wisconsin, USA, May 2-4, 2002.
11. (Invited Paper) J. Seo, C. Kuyper, D.T. Chiu, and L. P. Lee, "Biophotonic MEMS for Single Molecule Detection and Manipulation," IEEE-EMBS Proceedings on Microtechnologies in Medicine & Biology, pp. 363-368, Madison, Wisconsin, USA, May 2-4, 2002.
12. K. Jeong and L. P. Lee, "A New Method of Increasing Numerical Aperture of Microlens for Biophotonic MEMS," IEEE-EMBS Proceedings on Microtechnologies in Medicine & Biology, pp. 380-383, Madison, Wisconsin, USA, May 2-4, 2002.
13. D. Di Carlo and L. P. Lee, "Mechanical Cell Lysis Results of A Sample Preparation Module for Functional Genomics," IEEE-EMBS Proceedings on Microtechnologies in Medicine & Biology, pp. 527-530, Madison, Wisconsin, USA, May 2-4, 2002.
14. S. Kwon, V. Milanovic, and L. P. Lee, "Vertical Microlens Scanner for 3D Imaging," Proc. of Solid-State Sensor and Actuator Workshop, pp. 227-230, Hilton Head, S.C., June 2002.
15. V. Milanovic, S. Kwon, and L. P. Lee, "Monolithic Vertical Combdrive Actuators for Adaptive Optics," IEEE/LEOS Optical MEMS 2002, pp. 57-58, Lugano, Switzerland, August 22-24, 2002.
16. J. Seo, S. Oh, and L. P. Lee, "Single Layer 2-D Optical Scanners with Integrated Polymer Microlens," IEEE/LEOS Optical MEMS 2002, pp. 151-152, Lugano, Switzerland, August 22-24, 2002.
17. S. Kwon, V. Milanovic, and L. P. Lee, "A High Aspect Ratio 2D Gimbaled Microscanner with Large Static Rotation," IEEE/LEOS Optical MEMS 2002, pp. 149-150, Lugano, Switzerland, August 22-24, 2002.
18. K. Jeong; M. Pio, C. Keller, L. P. Lee, "Piconewton Regime Measurements of Biomolecular Interactions by Nanomechanical Force Gauge," Proceedings of IEEE Nanotechnology 2002, pp. 129-132, Aug. 26-28, 2002
19. (Invited Paper) L. P. Lee, "BioPOEMS & Nanogap DNA Junctions," Proceedings of Micro Total Analysis Systems 2002, pp. 341-343, Nara, Japan, November 3-7, 2002.
20. J. Seo and L. P. Lee, "Integrated Microfluidic Optical Systems with LED" Proceedings of Micro-Total Analysis Systems 2002, pp 284-287, Nara, Japan, November 3-7, 2002.
21. J. Lee, S. Oh, Y. Choi, and L. P. Lee, "Label Free Dielectric Detection of DNA Hybridization with Nanogap Junctions," Proceedings of Micro-Total Analysis Systems 2002, pp. 305-307, Nara, Japan, November 3-7, 2002.
22. P. Leung, J. Seo and L. P. Lee, "A Multi-stage Micro-tangential Flow Filtration Devices for Micro Total Analysis Systems" Proceedings of Micro-Total Analysis Systems 2002, pp 380-382, Nara, Japan, November 3-7, 2002.
23. N. Chronis and L. P. Lee, "Polymer-based Actuators Integrated Into Microfluidic Systems," Proceedings of Micro Total Analysis Systems 2002, pp. 754-756, Nara, Japan, November 3-7, 2002.
24. K. Cheung, Y. Choi, T. Kubow, and L. P. Lee, "Nanostructured Electrodes for Neural Chip Applications," Proceedings of on Micro Total Analysis Systems 2002, pp. 778-780, Nara, Japan, November 3-7, 2002.
25. D. Di Carlo and L. P. Lee, "Enhanced Velocity Gradients Within Microfluidics for Cellular Manipulations," Proceedings of Micro Total Analysis Systems 2002, pp. 799-801, Nara, Japan, November 3-7, 2002.
26. W. Chang, L. P. Lee, and D. Liepmann "Cell Separation with Transient Adhesions," Proceedings of International Conference on Micro Total Analysis Systems 2002, pp. 820-822, Nara, Japan, November 3-7, 2002.
27. (Invited Paper) L. P. Lee, ""Molecular Nanoelectronics for Label Free DNA Analysis," Microprocesses and Nanotechnology Conference 2002 (NMC'02), pp. 286-287, Tokyo, Japan, November 8-11, 2002.

2001

Proceedings

1. D. Trebotich, W. Chang, L. P. Lee and D. Liepmann, "Numerical Models of Blood Flow in Simple Microchannels," Fourth International Conference on Modeling and Simulation of Microsystems, Hilton Head Island, South Carolina, U.S.A., March 19-21, 2001.
2. S. Kwon and L. P. Lee, "Focal Length Control by Microfabricated Planar Electrodes-based Liquid Lens ( PELL)," Proceedings of Transducers'01, pp. 1348-51 (11th International Conference on Solid-State Sensors and Actuators), Munich, Germany, June 10-14, 2001.
3. N. Chronis, W. Lam, and L. P. Lee, "A microfabricated bio-magnetic separator based on continuous hydrodynamic parallel flow," Fifth International Conference on Miniaturized Chemical and Biochemical Analysis Systems ( TAS 2001); Monterey, CA, October 21-25, 2001.
4. K. Jeong, S. Oh, and L. P. Lee, "Hydrophobic sealing for integrated microactuators in biofluidic systems," Fifth International Conference on Miniaturized Chemical and Biochemical Analysis Systems ( TAS 2001); Monterey, CA, October 21-25, 2001.
5. J. Seo and L. P. Lee, "Selective plasma surface modification for self-aligned microlense arrays on microfluidic systems," Fifth International Conference on Miniaturized Chemical and Biochemical Analysis Systems (TAS 2001); Monterey, CA, October 21-25, 2001.

2000

Proceedings

1. K. Cheung, G. Lee, K. Djupsund, Y. Dan, and L. P. Lee, "A New Neural Probe Using SOI Wafers with Topological Interlocking Mechanisms," IEEE-EMBS Proceeding on Microtechnologies in Medicine & Biology, Lyon, FRANCE, pp.07-511, October 12-14, 2000.
2. D. Di Carlo, W. Chang, and L. P. Lee, "Simulation of Near-Field Excitation and Trapping for Integrated Near-Field Optical and Microfluidic Devices," IEEE-EMBS Proceeding on Microtechnologies in Medicine & Biology, Lyon, FRANCE, pp. 411-414, October 12-14, 2000.
3. W. Chang, D, Trebotich, L. P. Lee, and D. Liepmann, "Blood Flow in Simple Microchannels," IEEE-EMBS Proceeding on Microtechnologies in Medicine & Biology, Lyon, FRANCE, pp. 311-315, October 12-14, 2000.
4. G. Lee, K. Cheung, W. Chang, and L. P. Lee, "Mechanical Interlocking with Precisely Controlled Nano- and Microscale Geometries for Implantable Microdevices," IEEE-EMBS Proceeding on Microtechnologies in Medicine & Biology, FRANCE, pp. 537-541, October 12-14, 2000.

1988-1998

Journal Articles

1. L. P. Lee, S. A. Berger, D. Liepmann, and L. Pruitt, "High Aspect Ratio Polymer Microstructures and Cantilevers for BioMEMS Using Low Energy Ion Beam and Photolithography," Sensors and Actuators A. Physical, Vol. 71/1-2, pp. 144-149 (1998).
2. R. Cantor, L. P. Lee, A. Matlashov, and V. Vinetskiy, "A Low-noise, Two-stage DC SQUID Amplifier with High Bandwidth and Dynamic Range," IEEE Trans. Appl. Supercon. 7, pp. 3033-3036 (1997).
3. A. P. Marate, F. Ludwig, T. Van Duzer, and L. P. Lee, "A Novel Planarization Technique for a High-Tc? Multilevel IC Process," IEEE Trans. Appl. Supercon. 7, pp. 3834-3837 (1997).
4. Y. Huang, K. L. Merkle, L. P. Lee, M. Teepe, and K. Char, "Microstructural Origin of 1/f Noise in High-Tc??Bicrystal SQUID Magnetometers," Appl. Phys. Lett. 71, 3703-375 (1997).
5. R. Cantor, L. P. Lee, M. Teepe, V. Vinetskiy, "Low-noise, Single-layer YBa2Cu3O7-x DC SQUID Magnetometers at 77 K," IEEE Trans. Appl. Supercon. 5, 2927-2930 (1995).
6. L. P. Lee, J. Longo, V. Vinetskiy, and R. Cantor, "A Low-noise YBa2Cu3O7-x dc Superconducting Quantum Interference Device (SQUID) Magnetometer with Direct Signal Injection," Appl. Phys. Lett. 66, 1539-1543 (1995). pdf
7. L. P. Lee, M. Teepe, V. Vinetskiy, R. Cantor, and M. S. Colclough, "Key Elements for a Sensitive 77 Kelvin dc Superconducting Quantum Interference Device (SQUID) Magnetometer," Appl. Phys. Lett. 66, 3059-3062 (1995). pdf
8. A. P. Marate, F. Ludwig, T. Van Duzer, and L. P. Lee, "Process Issues and Components for HTS Digital Integrated Circuits Fabrication," IEEE Trans. Appl. Supercon. 5, 3135-3139 (1995).
9. P. R. de la Houssaye, M. J. Burns, W. J. Ruby, S. D. Russell, and L. P. Lee, "Demonstration of Monolithic Co-fabrication of YBa2Cu3O7-??and CMOS Devices on the Same Sapphire Substrate," IEEE Trans. Electron Devices, 40, 2139-2140 (1993).
10. M. J. Burns, P. R. de la Houssaye, S. D. Russell, G. A. Garcia, W. J. Ruby, and L. P. Lee, "Demonstration of YBa2Cu3O7-x and Complementary Metal-oxide-semiconductor Device Fabrication on the Same Sapphire Substrate," Appl. Phys. Lett. 63, 1282-1284 (1993). pdf
11. J. S. Martens, A. Pance, K. Char, L. P. Lee, S. R. Whiteley, and V. M. Hietala, "Superconducting Josephson Arrays as Tunable Microwave Sources Operating at 77 K," Appl. Phys. Lett. 63, 1681-1683 (1993).
12. J. S. Martens, K. Char, L. P. Lee, M. E. Johansson, S. R. Whiteley, K. E. Kihlstrom, J. R. Wendt, V. M. Hietala, T. A. Plut, G. A. Vawter, S. Y. Hou, J. M. Phillips, and W. Y. Lee, "Use of 2-Dimentional Arrays to Determine the Uniformity of Josephson Junctions," IEEE Trans. Appl. Supercon. 4, 3095-3098 (1993).
13. J. Clarke, J. Kingston, A. Miklich, F. Wellstood, K. Char, M. S. Colclough, L. P. Lee, G. Zaharchuk, "High-Tc Superconducting Multilayers for SQUID Magnetometers," Physica Scripta T 42, 51-56 (1992).
14. L. P. Lee, B. J. Burns, and K. Char, "Free-Standing Microstructure of High-Tc Superconducting Devices," Appl. Phys. Lett. 61, pp. 2706-2708 (1992). pdf
15. K. Char, M.S. Colclough, and L. P. Lee, "Extension of the Bi-epitaxial Josephson Junctions Processes to Various Substrates," Appl. Phys. Lett. 59, 2177-2179 (1991). pdf
16. K. Char, M. S. Colclough, L. P. Lee, and G. Zaharchuk, "Grain Boundary Josephson Junctions Created by Bi-epitaxial Processes," Physica C 185, 2561-2562 (1991).
17. L. P. Lee, K. Char, and M.S. Colclough, "Monolithic 77 K dc SQUID Magnetometers," Appl. Phys. Lett. 59, 3051-3053 (1991). pdf
18. J. A. Carpenter, A. D. Smith, Arambula, L. P. Lee, T. Nelson, and L. Yujiri, "100 GHz SIS Mixer with Improved RF Matching," IEEE Trans. Mag., 27, 2654-2559 (1991).
19. L. P. Lee, E. R. Arambula, G. Hanaya, C. Dang, R. Sandell, and H. Chan, "RHEA Process for Fine-Geometry Josephson Junction Fabrication," IEEE Trans. Mag., 27, 3133-3136 (1991).
20. A. Smith, J. Carpenter, D. Durand, and L. P. Lee, "On-Chip Diagnostic Equipment for 100 GHz Superconducting Circuits," IEEE Trans. Mag., 27, 3370-3373, (1991).
21. J. H. Kim, A. Larsson, and L. P. Lee, "Psedomorphic InyAl1-yGaAs/GaAs/AlxGa1-xAs Single Quantum-Well Surface-Emitting Lasers with Integrated 45o Beam Deflectors," Appl. Phys. Lett. 58, 7-9, (1991). pdf
22. J. H. Kim, R. J. Lang, A. Larsson, L. P. Lee, and A. A. Narayanan, "High-Power AlGaAs/GaAs Single Quantum-Well Surface-Emitting Lasers with Integrated 45o Beam Deflectors," Appl. Phys. Lett. 49, 2048-2050, (1990).
23. J. Murduck, J. Porter, W. Dozer, R. Sandell, and L. P. Lee, "Niobium Trilayer Process for Superconducting Circuits," IEEE Trans. Mag., 25, 1139-1242 (1989).
24. Yang, J. J., L. P. Lee, Jensen, M., Sergant, M., Ou, S. S., and Wilcox, J., "Monolithic Two Dimensional Surface Emitting Arrays of GaAs/AlGaAs Lasers," Fiber and Integrated Optics, 7, 217-221 (1988).

Proceedings

1. L. P. Lee, Berger, S. A., Pruitt, L., and Liepmann, D., "Key Elements of a Transparent Teflon® Microfluidic System," Proceedings of on Micro Total Analysis Systems, Banff, Canada, October 17-21, 1998.
2. J. M Schmidt, L. P. Lee, A. Matlashov, M. Teepe, V. Vinetskiy, R. Cantor, and M. DiIorio," "Low-Noise, Single Layer YBa2Cu3O7-x DC SQUID Magnetometer for Shielded and Unshielded Operation," Biomagnetism 96 Symposium, January 19-22, Los Alamos, New Mexico, 1996.
3. J. S. Martens, L. P. Lee, K. Char, and R. Withers, "mm-Wave Confocal Resonators for Vertical Structure Profiling in Semiconducting and Superconducting materials," Proceedings of IEEE MTT-S International Microwave Symposium Digest, 3, pp. 1243-1247, 1993.
4. P. R. de la Houssaye, M. Burns, W. Ruby, S. Russell, S. R. Clayton, G. A. Garcia, and L. P. Lee, "Demonstration of Monolithic Co-fabrication of Y1/Ba2Cu3O7-? and CMOS Devices on the Same Sapphire Substrate," Proceedings of Device Research Conference (51st Annual), pp. 148-149, June 21-23, 1993.
5. K. Char, M. S. Colclough, and L. P. Lee "Progress Towards an Integrated HTS SQUID Magnetometer, Superconducting Devices and Their Applications," H. Koch and H. Lubbig (Eds.) Springer-Verlag Berlin Heidelberg, pp. 162-167, 1992.
6. K. Char, M. S. Colclough, L. P. Lee, and G. Zaharchuck "Bi-epitaxial Josephson Junctions in YBa2Cu3O7 with Controlled 45-Degree Grain Boundaries," Proceedings of Advances in Superconductivity IV, Spinger-Verlag, Tokyo, pp. 871-876, 1992.
7. Kookrin Char, M. S. Colclough, Luke P. S. Lee, and G. Zaharchuk, "Multilayer superconducting devices made using biepitaxial grain boundary Josephson junctions in YBa2Cu3O7," Proc. SPIE Int. Soc. Opt. Eng. 1597, 90 (1992)
8. K. Char, M. S. Colclough, and L. P. Lee, "Progress Towards an Integrated HTS SQUID Magnetometer," Proceedings of International Conference SQUID '91, Berlin, Germany, June 18-21, 1991.
9. K. Char, M. S. Colclough, L. P. Lee, and G. Zaharchuk, "Grain Boundary Josephson Junctions Created by Bi-epitaxial Processes," Proceedings of the International Conference on Materials and Mechanism of Superconductivity, High temperature Superconductors III, Kanazawa, Japan, 1991.
10. E. L. Dines, B. J. Dalrymple, and L. P. Lee, "Application of Superconductive Electronics to LWIR Sensor System," Proceedings of the SPIE, vol. 1243, pp. 221-7, 1990
11. J. H. Kim, L. P. Lee, R. J. Lang, and A. Narayanan, "45o-Beam-Deflecting Single Quantum Well Surface-Emitting Lasers for Optoelctronic Neural Networks," IEEE/LEOS' 90 Proceeding, Boston, MA, Nov. 4-9, 1990.
12. J. Z. Wilcox, J. J. Yang, and L. P. Lee, "Two-dimensional Laser Diode Array Technologies," Society for Optical and Quantum Electronics Conference, Lake Tahoe, Nevada, CA Dec. 7-11, 1987.