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Yoonhee Kim, M.P.H, Ph.D.

kimyoo@mail.nih.gov

Research fellow Inherited Disease Research Branch, National Human Genome Research Institute, NIH 333 Cassell Drive Suite 1200 Baltimore, MD 21224 Office Phone: 443-740-2909 FAX: 443-740-2165

RESEARCH INTERESTS

Statistical genetics and genomics, genetic Epidemiology, bioinformatics, next generation sequencing data analysis

HONOR AND AWARDS

5/2012 NHGRI Diversity and Community Outreach GREAT Award for teaching at University of District of Columbia, Washington D.C 4/2012 Chief Judge for the Fellows Award for Research Excellence (FARE) 2013 in Genomics study section 6/2011 NIH FARE Award 2012 ($1,000) 8/2007 Graduate Partnership Program Travel Award ($2,000) 10/2005 – 8/2006 Pre-doctoral Training Fellowship $19,000 supported by Korea Research Foundation of Korea Government 2001 – 2005 Merit- based scholarships in Seoul National University

PUBLICATIONS (* co-first author)

K. C. Desch, A. B. Ozel, D. Siemieniak, Y. Kalish, C. Thornburg, A. Sharathkumar, C. McHugh, C. Laurie, A. Crenshaw, D. Mirel, Y. Kim, C. D. Cropp, A. M. Molloy, P. N. Kirke, J. E. Bailey-Wilson, A. F. Wilson, J. L. Mills, J. M. Scott, L. C. Brody, J. Z. Li and D. Ginsburg, “ Linkage Analysis Identifies a Novel Locus for Plasma von Willebrand Factor Undetected by Genome Wide Association”, in press, PNAS, 2012.

C. M. Justice*, G. Yagnik*, Y. Kim, I. Peter, E. W. Jabs, X. Ye, L. Shi, M.L. Cunningham, V. Kimonis, T. Roscioli, S. A. Wall, A. O.M. Wilkie, J. Stoler, J. T. Richtsmeier, Y. Heuze, P. A. Sanchez-Lara, M. F. Buckley, C. M. Druschel, J. L. Mills, M.Caggana, P. A. Romitti, D. M. Kay, C. Senders, P.J. Taub, O. D. Klein, J. Boggan, M. Zwienenberg-Lee, C. Naydenov, J. Kim, A.F. Wilson, S. A. Boyadijiev, “A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9”, doi:10.1038/ng.2463 Nature Genetics, 2012.

Y. Kirino, G. Bertsias, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, F. S.Sacli, B. Erer, Z. Emrence, A. Cakar, D. Ustek, C. Satorius, A. Ueda, M. Takeno, Y. Kim, M. J. Ombrello, A. Meguro, A. Gul, E.F. Remmers, D.L.Kastner, “A genome-wide association study identifies new susceptibility loci for Behcet’s disease and epistasis between HLA-B*51 and ERAP1”, in press Nature Genetics, 2012.

N. H. Miller, C. M. Justice, B. Marosy, K. Swindle, Y. Kim, MH. Roy-Gagnon, H. Sung, D. Behneman, K. F. Doheny, E. Pugh, A .F. Wilson “Fine-mapping and family-based association tests of idiopathic scoliosis on 9q31.3-134.3 and 16p12.3-q22.2,” Human Heredity, Vol 74, No. 1, 36-44, 2012.

N. N. Hansel, I. Ruczinski, N. Rafaels, D. D. Sin, D. Daley, A. Malinina, L. Huang, A. Sandford, M. Elliott, T. Murray, Y. Kim, C. Vergara, S. R. Heckbert, B. M. Psaty, G. Li, F. Aminuddin, J. Dupuis, G. O’Connor, M. Boezen, D.S.Postma, J.Smolonska, R. Crystal, T. Toshiko, L. Ferruci, E. Silverman, E. Wan, J. Vestbo, D. Lomas, J. Connett, R. A. Wise, E.R. Neptune, R. Mathias, P.D. Pare, T. H. Beaty, K. C. Barnes “Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD,” Human Genetics, DOI: 10.1007/s00439-012-1219-6, 2012. PMID: 22986903

M. J. Emond, T. Louie, J. Emerson, W. Zhao, R. A. Mathias, M. R. Knowles, F. A. Wright, M. J. Rieder, H.K. Tabor, D.A. Nickerson, K.C. Barnes, NHLBI GO Exome Sequencing Project, Lung GO (Y. Kim), R.L. Gibson & M.J. Bamshad “Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis,” Nature Genetics, Vol 44: 886–889, 2012.

S. P. David, A. Hamidovic, G. K. Chen, A.W. Bergen, J. Wessel, J.L. Kasberger, W. M. Brown, S. Petruzella, E. L. Thacker, Y. Kim, M.A. Nalls, G. J. Tranah, Y.J. Sung, AABC, AAPC, CHS, CARe, GeneSTAR, HANDLS, HealthABC, HyperGEN, WHI(SHARe), C.A. Haiman, H.Furberg, “Genome-wide meta-analyses of smoking behaviors in African Americans”, Translational Psychiatry, 2:e119; doi:10.1038/tp.2012.41, 2012.

Y. Kim*, Q. Li*, C.D. Cropp, H. Sung, J. Cai, C.L. Simpson, B.Perry, A.Dasgupta, J.D. Malley, A.F. Wilson, J.E. Bailey-Wilson “Performance of Random Forests and Logic Regression Methods Using Mini-Exome Sequence data,” BMC proceedings, Vol 5 (supp 9):S104, 2011. PMID: 22373484 PMCID: PMC3287827

J.E. Bailey-Wilson, J.S. Brennan, R. Culverhouse, Y. Kim, Y. Jiang, J. Jung, Q. Li, C. Scholosberg, L. Wang, Y.E. Yilmaz, H. Zhang, Z. Zhan, “Regression and Data Mining Methods for Analyses of Multiple Rare Variants in GAW17 “ Mini-Exome” data,” Genetic Epidemiology, Vol 35(supp 1):S92-S100, 2011. PMID: 22128066 PMCID: PMC3360949

H. Sung, Y. Kim, J. Cai, C.D. Cropp, C.L. Simpson, Q. Li, B. C Perry, A.J.M. Sorant, J.E. Bailey-Wilson, A.F. Wilson “A comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression,” BMC proceedings, Vol 5(supp 9):S15, 2011. PMID: 22373501 PMCID: PMC3287849

T.L. Assimes, H. Holm, ADVANCE, CATHGEN, GeneSTAR (Y. Kim), INTERHEART study groups, decode genetics, and T. Quertermous “Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies,” Journal of the American College of Cardiology, Vol 56, No 19, 2010. PMID: 20933357 PMCID: PMC3084526

R.A. Mathias*, Y. Kim*, H. Sung, R.Y. Yanek, J.E. Hererra-Galeano, I. Ruczinski, A.F. Wilson, N. Faraday, L.C. Becker, D.M. Becker “A Combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in Caucasian and African American families with coronary artery disease,” BMC Medical Genomics, 3:22, 2010. PMID: 20529293 PMCID: PMC2890666

Y. Kim, R. Wojciechowski, H. Sung, R.A. Mathias, L. Wang, A.P. Klein, R.K. Lenroot, J. Malley, J.E. Bailey-Wilson, “Evaluation of random forests performance for genome wide association studies in the presence of interaction effects,” BMC Proceedings, Vol3 (supp 7) s64, 2009. PMID: 20018058 PMCID: PMC2795965

Y. Kim, P. Duggal, E.M. Gillanders, H. Kim, J.E. Bailey-Wilson, “Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data,” Genetic Epidemiology; 32:41-51, 2008. PMID: 17685456 PMCID: PMC2216429

Y. Kim, H. Kim. “Application of Random Forests to Association Studies Using Mitochondrial Single Nucleotide Polymorphisms,” Genomics & Informatics Vol. 5 (4) 168-173, 2007.

Y. Kim, B. Doan, P. Duggal, J. E. Bailey-Wilson, “Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis,” BMC Genetics Proceedings, I (Supp 1) S152, 2007.

Sung J, Cho SI, Song YM, Lee K, Choi EY, Ha M, Kim J, Kim H, Kim Y, Shin EK, Kim YH, Yoo KY, Park C, Kimm K, “Do we need more twin studies? The Healthy Twin Study, Korea,” Int J Epidemiology, 35(2):488-90, 2006.

S.H. Lee, J.M. Park, S.J. Kwon, H. Kim, Y.H. Kim, J.K. Roh, and B.W. Yoon, “Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients,” Neurology, 63: 16-21, 2004.

S.H. Lee, H.J. Bae, S.J. Kwon, H. Kim, Y.H. Kim, B.W. Yoon, and J.K. Roh, “Cerebral microbleeds are regionally associated with intra cerebral hemorrhage,” Neurology, 62:72-76, 2004.

Y. Kim, W. Park, H. Kim, “An iterative normalization algorithm from cDNA microarray medical data analysis,” Vol.2 (2) 94-100, Genomics & Informatics, 2004.