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(Yoonhee Kim, M.P.H, Ph.D.)
(Yoonhee Kim, M.P.H, Ph.D.)
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== Yoonhee Kim, M.P.H, Ph.D. ==
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== '''Yoonhee Kim, M.P.H, Ph.D.''' ==
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kimyoo@mail.nih.gov
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Research fellow, Inherited Disease Research Branch
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Division of Clinical Pharmacology
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Office of Translational Sciences
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Center for Drug Evaluation and Research  
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U.S. Food and Drug Administration
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10903 New Hampshire Ave., Bldg 51 Room 2135
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Silver Spring, MD 20993-0002
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National Human Genome Research Institute (NHGRI)
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Tel: 240-402-3778
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Email: Yoonhee.kim@fda.hhs.gov
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National Institutes of Health (NIH)
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== RESEARCH INTEREST ==
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333 Cassell Drive Suite 1200,
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Statistical Genetics, Genetic Epidemiology, Clinical trials,
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Baltimore, MD 21224
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Next Generation Sequencing data analysis, GenexGene Interaction analysis using Machine Learning Methods (Random Forests)
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== EDUCATION ==
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EDUCATION
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2008 Ph.D. Seoul National University, School of Public Health
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----
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2003 M.P.H Seoul National University, School of Public Health
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2008      Ph.D. Biostatistics and Epidemiology, School of Public Health, Seoul National University
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2005-2008 Pre-doctoral training at National Human Genome Research Institute, National Institutes of Health, USA
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2001 B.S. Ewha Womans Univerisity
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2003      M.P.H. Biostatistcs and Epidemiology, School of Public Health, Seoul National University
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== PUBLICATION ==
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22 manuscripts published
 +
(* co-first author)
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2001      B.S. in Statistics and B.S. in Biology, Ewha Womans University
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Y. Kirino, Q. Zhou, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, S. Ugurlu, B. Eror, N. Abaci, D. Ustek, A. Meguro, A. Ueda, M. Takeno, H. Inoko, M. J. Ombrello, C. Satorius, B. Maskeri, J. C. Mullikin, H-W Sun, G. Gutierrez-Cruz, '''Y. Kim''', A. F. Wilson, D. L. Kastner, A. Gul, E. F. Remmers, “Targeted deep re-sequencing implicates the familial Mediterranean fever gene MEFV and the bacterial sensor TLR4 in Behcet’s disease”, in press '''''PNAS''''', 2013.
 +
N. N. Hansel, I. Ruczinski, N. Rafaels, D. D. Sin, D. Daley, A. Malinina, L. Huang, A. Sandford, M. Elliott, T. Murray, '''Y. Kim''', C. Vergara, S. R. Heckbert, B. M. Psaty, G. Li, F. Aminuddin, J. Dupuis, G. O’Connor, M. Boezen, D.S.Postma, J.Smolonska, R. Crystal, T. Toshiko, L. Ferruci, E. Silverman, E. Wan, J. Vestbo, D. Lomas, J. Connett, R. A. Wise, E.R. Neptune, R. Mathias, P.D. Pare, T. H. Beaty, K. C. Barnes “Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD,” '''''Human Genetics''''', 132(1):79-90, 2013.
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RESEARCH INTERESTS
 
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Statistical Genetics, Genomics, Genometrics, Genetic Epidemiology, Bioinformatics, Next Generation Sequencing(NGS) data analysis, Human genetics in Autism, Cardiovascular diseases, Lung health (COPD, PAH), Oral cleft, Craniosynostosis, Behcet's disease.
 
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K. C. Desch, A. B. Ozel, D. Siemieniak, Y. Kalish, C. Thornburg,  A. Sharathkumar, C. McHugh, C. Laurie, A. Crenshaw, D. Mirel, '''Y. Kim''', C. D. Cropp, A. M. Molloy,
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P. N. Kirke, J. E. Bailey-Wilson, A. F. Wilson, J. L. Mills,  J. M. Scott, L. C. Brody, J. Z. Li and D. Ginsburg, “ Linkage Analysis Identifies a Novel Locus for Plasma von Willebrand
 +
Factor Undetected by Genome Wide Association”, doi:10.1073/pnas.1219885110,  '''''PNAS''''', 2012.
 +
C. M. Justice*, G. Yagnik*, '''Y. Kim''', I. Peter, E. W. Jabs, X. Ye, L. Shi, M.L. Cunningham, V. Kimonis, T. Roscioli, S. A. Wall, A. O.M. Wilkie, J. Stoler, J. T. Richtsmeier, Y. Heuze, P. A. Sanchez-Lara, M. F. Buckley, C. M. Druschel, J. L. Mills, M.Caggana, P. A. Romitti, D. M. Kay, C. Senders, P.J. Taub, O. D. Klein, J. Boggan, M. Zwienenberg-Lee, C. Naydenov, J. Kim,  A.F. Wilson, S. A. Boyadijiev, “A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9”, doi:10.1038/ng.2463 '''''Nature Genetics''''', 44, 1360-1364, 2012.
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HONOR AND AWARDS
 
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Y. Kirino, G. Bertsias, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, F. S.Sacli, B. Erer, Z. Emrence, A. Cakar, D. Ustek, C. Satorius, A. Ueda, M. Takeno, '''Y. Kim''', M. J. Ombrello, A. Meguro, A. Gul, E.F. Remmers, D.L.Kastner, “A genome-wide association study identifies new susceptibility loci for Behcet’s disease and epistasis between HLA-B*51 and ERAP1”, '''''Nature Genetics'''''45(2): 202-207, 2013.
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2012 NHGRI Diversity and Community Outreach GREAT Award for teaching at University of District of Columbia, Washington D.C.
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N. H. Miller, C. M. Justice, B. Marosy, K. Swindle,''' Y. Kim''', MH. Roy-Gagnon, H. Sung, D. Behneman, K. F. Doheny, E. Pugh, A .F. Wilson “Fine-mapping and family-based association tests of idiopathic scoliosis on 9q31.3-134.3 and 16p12.3-q22.2,” '''''Human Heredity''''', Vol 74, No. 1, 36-44, 2012.
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2012 Chief Judge for the Fellows Award for Research Excellence (FARE) 2013 in Genomics study section
 
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2011 NIH FARE Award 2012
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M. J. Emond, T. Louie, J. Emerson, W. Zhao, R. A. Mathias, M. R. Knowles, F. A. Wright, M. J. Rieder, H.K. Tabor, D.A. Nickerson, K.C. Barnes, NHLBI GO Exome Sequencing Project, Lung GO ('''Y. Kim'''), R.L. Gibson & M.J. Bamshad “Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis,” '''''Nature Genetics''''', Vol 44: 886–889, 2012.
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2007 Graduate Partnership Program Travel Award
 
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2005    Pre-doctoral Training Fellowship supported by Korea Research Foundation of Korea Government
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S. P. David, A. Hamidovic, G. K. Chen, A.W. Bergen, J. Wessel, J.L. Kasberger, W. M. Brown, S. Petruzella, E. L. Thacker, '''Y. Kim''', M.A. Nalls, G. J. Tranah, Y.J. Sung, AABC, AAPC, CHS, CARe, GeneSTAR, HANDLS, HealthABC, HyperGEN, WHI(SHARe), C.A. Haiman, H.Furberg, “Genome-wide meta-analyses of smoking behaviors in African Americans”, '''''Translational Psychiatry''''', 2:e119; doi:10.1038/tp.2012.41, 2012.
 +
'''Y. Kim'''*, Q. Li*, C.D. Cropp, H. Sung, J. Cai, C.L. Simpson, B.Perry, A.Dasgupta, J.D. Malley, A.F. Wilson, J.E. Bailey-Wilson “Performance of Random Forests and Logic Regression Methods Using Mini-Exome Sequence data,” '''''BMC proceedings''''', Vol 5 (supp 9):S104, 2011. PMID: 22373484 PMCID: PMC3287827
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PUBLICATIONS
 
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J.E. Bailey-Wilson, J.S. Brennan, R. Culverhouse, '''Y. Kim''', Y. Jiang, J. Jung, Q. Li, C. Scholosberg, L. Wang, Y.E. Yilmaz, H. Zhang, Z. Zhan, “Regression and Data Mining Methods for Analyses of Multiple Rare Variants in GAW17 “ Mini-Exome” data,”  '''''Genetic Epidemiology''''', Vol 35(supp 1):S92-S100, 2011. PMID: 22128066 PMCID: PMC3360949
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(* co-first author).
 
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K. C. Desch, A. B. Ozel, D. Siemieniak, Y. Kalish, C. Thornburg,  A. Sharathkumar, C. McHugh, C. Laurie, A. Crenshaw, D. Mirel, [[Y. Kim]], C. D. Cropp, A. M. Molloy,
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H. Sung, '''Y. Kim''', J. Cai, C.D. Cropp, C.L. Simpson, Q. Li, B. C Perry, A.J.M. Sorant, J.E. Bailey-Wilson, A.F. Wilson “A comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression,” '''''BMC proceedings''''', Vol 5(supp 9):S15, 2011. PMID: 22373501 PMCID: PMC3287849
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P. N. Kirke, J. E. Bailey-Wilson, A. F. Wilson, J. L. Mills, J. M. Scott, L. C. Brody, J. Z. Li and D. Ginsburg, “ Linkage Analysis Identifies a Novel Locus for Plasma von Willebrand
+
 
-
Factor Undetected by Genome Wide Association”, in press, PNAS, 2012.
+
 
 +
T.L. Assimes, H. Holm, ADVANCE, CATHGEN, GeneSTAR ('''Y. Kim'''), INTERHEART study groups, decode genetics, and T. Quertermous “Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies,” '''''Journal of the American College of Cardiology''''', Vol 56, No 19, 2010. PMID: 20933357 PMCID: PMC3084526
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C. M. Justice*, G. Yagnik*, [[Y. Kim]], I. Peter, E. W. Jabs, X. Ye, L. Shi, M.L. Cunningham, V. Kimonis, T. Roscioli, S. A. Wall, A. O.M. Wilkie, J. Stoler, J. T. Richtsmeier, Y. Heuze, P. A. Sanchez-Lara, M. F. Buckley, C. M. Druschel, J. L. Mills, M.Caggana, P. A. Romitti, D. M. Kay, C. Senders, P.J. Taub, O. D. Klein, J. Boggan, M. Zwienenberg-Lee, C. Naydenov, J. Kim,  A.F. Wilson, S. A. Boyadijiev, “A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9”, doi:10.1038/ng.2463 Nature Genetics, 2012.
 
-
Y. Kirino, G. Bertsias, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, F. S.Sacli, B. Erer, Z. Emrence, A. Cakar, D. Ustek, C. Satorius, A. Ueda, M. Takeno, [[Y. Kim]], M. J. Ombrello, A. Meguro, A. Gul, E.F. Remmers, D.L.Kastner, “A genome-wide association study identifies new susceptibility loci for Behcet’s disease and epistasis between HLA-B*51 and ERAP1”, in press Nature Genetics, 2012.
+
R.A. Mathias*, '''Y. Kim'''*, H. Sung, R.Y. Yanek, J.E. Hererra-Galeano, I. Ruczinski, A.F. Wilson, N. Faraday, L.C. Becker, D.M. Becker “A Combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in Caucasian and African American families with coronary artery disease,” '''''BMC Medical Genomics''''', 3:22, 2010. PMID: 20529293 PMCID: PMC2890666
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N. H. Miller, C. M. Justice, B. Marosy, K. Swindle,[[ Y. Kim]], MH. Roy-Gagnon, H. Sung, D. Behneman, K. F. Doheny, E. Pugh, A .F. Wilson “Fine-mapping and family-based association tests of idiopathic scoliosis on 9q31.3-134.3 and 16p12.3-q22.2,” Human Heredity, Vol 74, No. 1, 36-44, 2012.
 
-
N. N. Hansel, I. Ruczinski, N. Rafaels, D. D. Sin, D. Daley, A. Malinina, L. Huang, A. Sandford, M. Elliott, T. Murray, [[Y. Kim]], C. Vergara, S. R. Heckbert, B. M. Psaty, G. Li, F. Aminuddin, J. Dupuis, G. O’Connor, M. Boezen, D.S.Postma, J.Smolonska, R. Crystal, T. Toshiko, L. Ferruci, E. Silverman, E. Wan, J. Vestbo, D. Lomas, J. Connett, R. A. Wise, E.R. Neptune, R. Mathias, P.D. Pare, T. H. Beaty, K. C. Barnes “Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD,” Human Genetics, DOI: 10.1007/s00439-012-1219-6, 2012.
+
'''Y. Kim''', R. Wojciechowski, H. Sung, R.A. Mathias, L. Wang, A.P. Klein, R.K. Lenroot, J. Malley, J.E. Bailey-Wilson, “Evaluation of random forests performance for genome wide association studies in the presence of interaction effects,” '''''BMC Proceedings''''', Vol3 (supp 7) s64, 2009. PMID: 20018058 PMCID: PMC2795965
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M. J. Emond, T. Louie, J. Emerson, W. Zhao, R. A. Mathias, M. R. Knowles, F. A. Wright, M. J. Rieder, H.K. Tabor, D.A. Nickerson, K.C. Barnes, NHLBI GO Exome Sequencing Project, Lung GO ([[Y. Kim]]), R.L. Gibson & M.J. Bamshad “Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis,” Nature Genetics, Vol 44: 886–889, 2012.
 
-
S. P. David, A. Hamidovic, G. K. Chen, A.W. Bergen, J. Wessel, J.L. Kasberger, W. M. Brown, S. Petruzella, E. L. Thacker, [[Y. Kim]], M.A. Nalls, G. J. Tranah, Y.J. Sung, AABC, AAPC, CHS, CARe, GeneSTAR, HANDLS, HealthABC, HyperGEN, WHI(SHARe), C.A. Haiman, H.Furberg, “Genome-wide meta-analyses of smoking behaviors in African Americans”, Translational Psychiatry, 2:e119; doi:10.1038/tp.2012.41, 2012.
+
'''Y. Kim''', P. Duggal, E.M. Gillanders, H. Kim, J.E. Bailey-Wilson, “Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data,” '''''Genetic Epidemiology'''''; 32:41-51, 2008. PMID: 17685456 PMCID: PMC2216429
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[[Y. Kim]]*, Q. Li*, C.D. Cropp, H. Sung, J. Cai, C.L. Simpson, B.Perry, A.Dasgupta, J.D. Malley, A.F. Wilson, J.E. Bailey-Wilson “Performance of Random Forests and Logic Regression Methods Using Mini-Exome Sequence data,” BMC proceedings, Vol 5 (supp 9):S104, 2011.
+
'''Y.Kim''', “Genetic epidemiology 101: A review of the statistical basis,” '''''BioWave''''' Vol. 10 (13):1, 2008.  
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J.E. Bailey-Wilson, J.S. Brennan, R. Culverhouse, [[Y. Kim]], Y. Jiang, J. Jung, Q. Li, C. Scholosberg, L. Wang, Y.E. Yilmaz, H. Zhang, Z. Zhan, “Regression and Data Mining Methods for Analyses of Multiple Rare Variants in GAW17 “ Mini-Exome” data,”  Genetic Epidemiology, Vol 35(supp 1):S92-S100, 2011.
 
-
H. Sung, [[Y. Kim]], J. Cai, C.D. Cropp, C.L. Simpson, Q. Li, B. C Perry,  A.J.M. Sorant, J.E. Bailey-Wilson, A.F. Wilson “A comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression,” BMC proceedings, Vol 5(supp 9):S15, 2011.  
+
'''Y. Kim''', H. Kim. “Application of Random Forests to Association Studies Using Mitochondrial Single Nucleotide Polymorphisms,” '''''Genomics & Informatics''''' Vol. 5 (4) 168-173, 2007.
-
T.L. Assimes, H. Holm, ADVANCE, CATHGEN, GeneSTAR ([[Y. Kim]]), INTERHEART study groups, decode genetics, and T. Quertermous “Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies,” Journal of the American College of Cardiology, Vol 56, No 19, 2010.
 
-
R.A. Mathias*, [[Y. Kim]]*, H. Sung, R.Y. Yanek, J.E. Hererra-Galeano, I. Ruczinski, A.F. Wilson, N. Faraday, L.C. Becker, D.M. Becker “A Combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in Caucasian and African American families with coronary artery disease,” BMC Medical Genomics, 3:22, 2010.  
+
'''Y. Kim''', B. Doan, P. Duggal, J. E. Bailey-Wilson, “Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis,” '''''BMC Genetics Proceedings''''', I (Supp 1) S152, 2007.  
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[[Y. Kim]], R. Wojciechowski, H. Sung, R.A. Mathias, L. Wang, A.P. Klein, R.K. Lenroot, J. Malley, J.E. Bailey-Wilson, “Evaluation of random forests performance for genome wide association studies in the presence of interaction effects,” BMC Proceedings, Vol3 (supp 7) s64, 2009.
 
-
[[Y. Kim]], P. Duggal, E.M. Gillanders, H. Kim, J.E. Bailey-Wilson, “Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data,” Genetic Epidemiology; 32:41-51, 2008.  
+
Sung J, Cho SI, Song YM, Lee K, Choi EY, Ha M, Kim J, Kim H, Kim Y, Shin EK, Kim YH, Yoo KY, Park C, Kimm K, “Do we need more twin studies? The Healthy Twin Study, Korea,” '''''Int J Epidemiology''''', 35(2):488-90, 2006.
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[[Y. Kim]], H. Kim. “Application of Random Forests to Association Studies Using Mitochondrial Single Nucleotide Polymorphisms,” Genomics & Informatics Vol. 5 (4) 168-173, 2007.
 
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[[Y. Kim]], B. Doan, P. Duggal, J. E. Bailey-Wilson, “Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis,” BMC Genetics Proceedings, I (Supp 1) S152, 2007.  
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S.H. Lee, J.M. Park, S.J. Kwon, H. Kim, '''Y.H. Kim''', J.K. Roh, and B.W. Yoon, “Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients,” '''''Neurology''''', 63: 16-21, 2004.
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Sung J, Cho SI, Song YM, Lee K, Choi EY, Ha M, Kim J, Kim H, [[Kim Y]], Shin EK, Kim YH, Yoo KY, Park C, Kimm K, “Do we need more twin studies? The Healthy Twin Study, Korea,” Int J Epidemiology, 35(2):488-90, 2006.
 
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S.H. Lee, J.M. Park, S.J. Kwon, H. Kim, [[Y.H. Kim]], J.K. Roh, and B.W. Yoon, “Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients,” Neurology, 63: 16-21, 2004.
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S.H. Lee, H.J. Bae, S.J. Kwon, H. Kim, '''Y.H. Kim''', B.W. Yoon, and J.K. Roh, “Cerebral microbleeds are regionally associated with intra cerebral hemorrhage,” '''''Neurology''''', 62:72-76, 2004.
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S.H. Lee, H.J. Bae, S.J. Kwon, H. Kim, [[Y.H. Kim]], B.W. Yoon, and J.K. Roh, “Cerebral microbleeds are regionally associated with intra cerebral hemorrhage,”  Neurology, 62:72-76, 2004.
 
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[[Y. Kim]], W. Park, H. Kim, “An iterative normalization algorithm from cDNA microarray medical data analysis,” Vol.2 (2) 94-100, Genomics & Informatics, 2004.
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'''Y. Kim''', W. Park, H. Kim, “An iterative normalization algorithm from cDNA microarray medical data analysis,” '''''Genomics & Informatics''''', Vol.2 (2) 94-100, 2004.

Revision as of 12:45, 8 April 2013

Contents

Yoonhee Kim, M.P.H, Ph.D.

Division of Clinical Pharmacology Office of Translational Sciences Center for Drug Evaluation and Research U.S. Food and Drug Administration 10903 New Hampshire Ave., Bldg 51 Room 2135 Silver Spring, MD 20993-0002

Tel: 240-402-3778 Email: Yoonhee.kim@fda.hhs.gov

RESEARCH INTEREST

Statistical Genetics, Genetic Epidemiology, Clinical trials,

Next Generation Sequencing data analysis, GenexGene Interaction analysis using Machine Learning Methods (Random Forests)

EDUCATION

2008 Ph.D. Seoul National University, School of Public Health

2003 M.P.H Seoul National University, School of Public Health

2001 B.S. Ewha Womans Univerisity

PUBLICATION

22 manuscripts published (* co-first author)

Y. Kirino, Q. Zhou, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, S. Ugurlu, B. Eror, N. Abaci, D. Ustek, A. Meguro, A. Ueda, M. Takeno, H. Inoko, M. J. Ombrello, C. Satorius, B. Maskeri, J. C. Mullikin, H-W Sun, G. Gutierrez-Cruz, Y. Kim, A. F. Wilson, D. L. Kastner, A. Gul, E. F. Remmers, “Targeted deep re-sequencing implicates the familial Mediterranean fever gene MEFV and the bacterial sensor TLR4 in Behcet’s disease”, in press PNAS, 2013.


N. N. Hansel, I. Ruczinski, N. Rafaels, D. D. Sin, D. Daley, A. Malinina, L. Huang, A. Sandford, M. Elliott, T. Murray, Y. Kim, C. Vergara, S. R. Heckbert, B. M. Psaty, G. Li, F. Aminuddin, J. Dupuis, G. O’Connor, M. Boezen, D.S.Postma, J.Smolonska, R. Crystal, T. Toshiko, L. Ferruci, E. Silverman, E. Wan, J. Vestbo, D. Lomas, J. Connett, R. A. Wise, E.R. Neptune, R. Mathias, P.D. Pare, T. H. Beaty, K. C. Barnes “Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD,” Human Genetics, 132(1):79-90, 2013.


K. C. Desch, A. B. Ozel, D. Siemieniak, Y. Kalish, C. Thornburg, A. Sharathkumar, C. McHugh, C. Laurie, A. Crenshaw, D. Mirel, Y. Kim, C. D. Cropp, A. M. Molloy, P. N. Kirke, J. E. Bailey-Wilson, A. F. Wilson, J. L. Mills, J. M. Scott, L. C. Brody, J. Z. Li and D. Ginsburg, “ Linkage Analysis Identifies a Novel Locus for Plasma von Willebrand Factor Undetected by Genome Wide Association”, doi:10.1073/pnas.1219885110, PNAS, 2012.


C. M. Justice*, G. Yagnik*, Y. Kim, I. Peter, E. W. Jabs, X. Ye, L. Shi, M.L. Cunningham, V. Kimonis, T. Roscioli, S. A. Wall, A. O.M. Wilkie, J. Stoler, J. T. Richtsmeier, Y. Heuze, P. A. Sanchez-Lara, M. F. Buckley, C. M. Druschel, J. L. Mills, M.Caggana, P. A. Romitti, D. M. Kay, C. Senders, P.J. Taub, O. D. Klein, J. Boggan, M. Zwienenberg-Lee, C. Naydenov, J. Kim, A.F. Wilson, S. A. Boyadijiev, “A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9”, doi:10.1038/ng.2463 Nature Genetics, 44, 1360-1364, 2012.


Y. Kirino, G. Bertsias, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, F. S.Sacli, B. Erer, Z. Emrence, A. Cakar, D. Ustek, C. Satorius, A. Ueda, M. Takeno, Y. Kim, M. J. Ombrello, A. Meguro, A. Gul, E.F. Remmers, D.L.Kastner, “A genome-wide association study identifies new susceptibility loci for Behcet’s disease and epistasis between HLA-B*51 and ERAP1”, Nature Genetics45(2): 202-207, 2013.


N. H. Miller, C. M. Justice, B. Marosy, K. Swindle, Y. Kim, MH. Roy-Gagnon, H. Sung, D. Behneman, K. F. Doheny, E. Pugh, A .F. Wilson “Fine-mapping and family-based association tests of idiopathic scoliosis on 9q31.3-134.3 and 16p12.3-q22.2,” Human Heredity, Vol 74, No. 1, 36-44, 2012.


M. J. Emond, T. Louie, J. Emerson, W. Zhao, R. A. Mathias, M. R. Knowles, F. A. Wright, M. J. Rieder, H.K. Tabor, D.A. Nickerson, K.C. Barnes, NHLBI GO Exome Sequencing Project, Lung GO (Y. Kim), R.L. Gibson & M.J. Bamshad “Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis,” Nature Genetics, Vol 44: 886–889, 2012.


S. P. David, A. Hamidovic, G. K. Chen, A.W. Bergen, J. Wessel, J.L. Kasberger, W. M. Brown, S. Petruzella, E. L. Thacker, Y. Kim, M.A. Nalls, G. J. Tranah, Y.J. Sung, AABC, AAPC, CHS, CARe, GeneSTAR, HANDLS, HealthABC, HyperGEN, WHI(SHARe), C.A. Haiman, H.Furberg, “Genome-wide meta-analyses of smoking behaviors in African Americans”, Translational Psychiatry, 2:e119; doi:10.1038/tp.2012.41, 2012.


Y. Kim*, Q. Li*, C.D. Cropp, H. Sung, J. Cai, C.L. Simpson, B.Perry, A.Dasgupta, J.D. Malley, A.F. Wilson, J.E. Bailey-Wilson “Performance of Random Forests and Logic Regression Methods Using Mini-Exome Sequence data,” BMC proceedings, Vol 5 (supp 9):S104, 2011. PMID: 22373484 PMCID: PMC3287827


J.E. Bailey-Wilson, J.S. Brennan, R. Culverhouse, Y. Kim, Y. Jiang, J. Jung, Q. Li, C. Scholosberg, L. Wang, Y.E. Yilmaz, H. Zhang, Z. Zhan, “Regression and Data Mining Methods for Analyses of Multiple Rare Variants in GAW17 “ Mini-Exome” data,” Genetic Epidemiology, Vol 35(supp 1):S92-S100, 2011. PMID: 22128066 PMCID: PMC3360949


H. Sung, Y. Kim, J. Cai, C.D. Cropp, C.L. Simpson, Q. Li, B. C Perry, A.J.M. Sorant, J.E. Bailey-Wilson, A.F. Wilson “A comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression,” BMC proceedings, Vol 5(supp 9):S15, 2011. PMID: 22373501 PMCID: PMC3287849


T.L. Assimes, H. Holm, ADVANCE, CATHGEN, GeneSTAR (Y. Kim), INTERHEART study groups, decode genetics, and T. Quertermous “Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies,” Journal of the American College of Cardiology, Vol 56, No 19, 2010. PMID: 20933357 PMCID: PMC3084526


R.A. Mathias*, Y. Kim*, H. Sung, R.Y. Yanek, J.E. Hererra-Galeano, I. Ruczinski, A.F. Wilson, N. Faraday, L.C. Becker, D.M. Becker “A Combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in Caucasian and African American families with coronary artery disease,” BMC Medical Genomics, 3:22, 2010. PMID: 20529293 PMCID: PMC2890666


Y. Kim, R. Wojciechowski, H. Sung, R.A. Mathias, L. Wang, A.P. Klein, R.K. Lenroot, J. Malley, J.E. Bailey-Wilson, “Evaluation of random forests performance for genome wide association studies in the presence of interaction effects,” BMC Proceedings, Vol3 (supp 7) s64, 2009. PMID: 20018058 PMCID: PMC2795965


Y. Kim, P. Duggal, E.M. Gillanders, H. Kim, J.E. Bailey-Wilson, “Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data,” Genetic Epidemiology; 32:41-51, 2008. PMID: 17685456 PMCID: PMC2216429

Y.Kim, “Genetic epidemiology 101: A review of the statistical basis,” BioWave Vol. 10 (13):1, 2008.


Y. Kim, H. Kim. “Application of Random Forests to Association Studies Using Mitochondrial Single Nucleotide Polymorphisms,” Genomics & Informatics Vol. 5 (4) 168-173, 2007.


Y. Kim, B. Doan, P. Duggal, J. E. Bailey-Wilson, “Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis,” BMC Genetics Proceedings, I (Supp 1) S152, 2007.


Sung J, Cho SI, Song YM, Lee K, Choi EY, Ha M, Kim J, Kim H, Kim Y, Shin EK, Kim YH, Yoo KY, Park C, Kimm K, “Do we need more twin studies? The Healthy Twin Study, Korea,” Int J Epidemiology, 35(2):488-90, 2006.


S.H. Lee, J.M. Park, S.J. Kwon, H. Kim, Y.H. Kim, J.K. Roh, and B.W. Yoon, “Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients,” Neurology, 63: 16-21, 2004.


S.H. Lee, H.J. Bae, S.J. Kwon, H. Kim, Y.H. Kim, B.W. Yoon, and J.K. Roh, “Cerebral microbleeds are regionally associated with intra cerebral hemorrhage,” Neurology, 62:72-76, 2004.


Y. Kim, W. Park, H. Kim, “An iterative normalization algorithm from cDNA microarray medical data analysis,” Genomics & Informatics, Vol.2 (2) 94-100, 2004.

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