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(Yoonhee Kim, M.P.H, Ph.D.)
 
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== '''Yoonhee Kim, M.P.H, Ph.D.''' ==
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Division of Clinical Pharmacology
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Office of Translational Sciences
 +
Center for Drug Evaluation and Research
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U.S. Food and Drug Administration
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10903 New Hampshire Ave., Bldg 51 Room 2135
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Silver Spring, MD 20993-0002
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== '''Yoonhee Kim, MPH, Ph.D''' ==
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Email: Yoonhee.kim@fda.hhs.gov
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Postdoctoral fellow
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== RESEARCH INTEREST ==
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Genometrics section (Dr. Alexander F. Wilson)
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Statistical Genetics, Genetic Epidemiology, Clinical trials,
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Inherited Disease Research Branch
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Next Generation Sequencing data analysis, GenexGene Interaction analysis using Machine Learning Methods (Random Forests)
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National Human Genome Research Institute
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== EDUCATION ==
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National Institute of Health
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2008 Ph.D. in Epidemiology and Biostatistics, Seoul National University, School of Public Health, Korea
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Email : '''wondernina@hotmail.com'''
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2003 M.P.H in Epidemiology and Biostatistics, Seoul National University, School of Public Health, Korea
 +
2001 B.S. in Statistics and Biology (double majors) Ewha Womans Univerisity, Korea
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== '''Education''' ==
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== EMPLOYMENT ==
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* 1997 - 2001 BS in Statistics, and BS in Biology, Ewha Women's University, Seoul, Korea
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2008-2012 Research Fellow (Statistical geneticist), National Human Genome Research Institute, National Institutes of Health, USA
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+
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* 2001 - 2003 MPH in Biostatistics and Epidemiology, School of Public Health, Seoul National University, Seoul, Korea
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* 2003 – 2008         Ph.D. in Biostatistics and Epidemiology, School of Public Health, Seoul National University, Seoul, Korea
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2005-2008 Visiting Fellow, Predoctoral trainee, National Human Genome Research Institute, National Institutes of Health, USA
 +
== PUBLICATION ==
 +
23 manuscripts published
 +
(* co-first author)
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== '''Predoctoral Training and Fellowship Appointments''' ==
 
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* 2005 – 2007 :  Predoctoral trainee in Statistical Genetics ([http://www.genome.gov/10000339 Dr. Joan E. Bailey-Wilson]), IDRB/NHGRI/NIH, Maryland, USA
 
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* 2005 – 2006  :  Predoctoral trainee awards by Korea Research Foundation (KRF-2005-213-C00007)
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'''Y. Kim''', B. Suktitipat, L. R. Yanek, N. Faraday, A.F. Wilson, D.M. Becker, L.C. Becker, R.A. Mathias, “Targeted deep re-sequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation”, in press '''''PLoS One''''', 2013.
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* 2007 – 2008  :  Predoctoral trainee in Genometrics ([http://www.genome.gov/10000710 Dr. Alexander F. Wilson]), IDRB/NHGRI/NIH, Maryland, USA
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* 2008 – present :  Postdoctoral fellow in Genometrics ([http://www.genome.gov/10000710 Dr. Alexander F. Wilson]), IDRB/NHGRI/NIH, Maryland, USA
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== '''Ongoing Projects''' ==
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Y. Kirino, Q. Zhou, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, S. Ugurlu, B. Eror, N. Abaci, D. Ustek, A. Meguro, A. Ueda, M. Takeno, H. Inoko, M. J. Ombrello, C. Satorius, B. Maskeri, J. C. Mullikin, H-W Sun, G. Gutierrez-Cruz, '''Y. Kim''', A. F. Wilson, D. L. Kastner, A. Gul, E. F. Remmers, “Targeted deep re-sequencing implicates the familial Mediterranean fever gene MEFV and the bacterial sensor TLR4 in Behcet’s disease”, in press '''''PNAS''''', 2013.
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* Analyzed data using SAS, R, SIBPAIR, S.A.G.E, SOLAR and Perl script, ''Genotypic Determinants of Aspirin Response in High Risk Families'' with Dr. Lewis C. Becker, School of Medicine, Johns Hopkins University, Baltimore, MD, U.S.A [http://www.jhufamilyheart.com JHU Sibling and Family Heart Study ]
 
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* Analyzed data using R, SIBPAIR, S.A.G.E, SOLAR and Perl script, ''Family based association studies vs Population based association studies'', NIH
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N. N. Hansel, I. Ruczinski, N. Rafaels, D. D. Sin, D. Daley, A. Malinina, L. Huang, A. Sandford, M. Elliott, T. Murray, '''Y. Kim''', C. Vergara, S. R. Heckbert, B. M. Psaty, G. Li, F. Aminuddin, J. Dupuis, G. O’Connor, M. Boezen, D.S.Postma, J.Smolonska, R. Crystal, T. Toshiko, L. Ferruci, E. Silverman, E. Wan, J. Vestbo, D. Lomas, J. Connett, R. A. Wise, E.R. Neptune, R. Mathias, P.D. Pare, T. H. Beaty, K. C. Barnes “Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD,” '''''Human Genetics''''', 132(1):79-90, 2013.
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* Managed and analyzed data using Sib pair, Merlin, and Genehunter, ''Nonparametric Linkage Analysis of Hypocholesterolemic Autism Patients and their families'' with Dr. Elaine Tierney, Kennedy Krieger Institute, Baltimore, MD, U.S.A [http://www.kennedykrieger.org Kennedy Krieger Institute]
 
 +
Y. Kirino, G. Bertsias, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, F. S.Sacli, B. Erer, Z. Emrence, A. Cakar, D. Ustek, C. Satorius, A. Ueda, M. Takeno, '''Y. Kim''', M. J. Ombrello, A. Meguro, A. Gul, E.F. Remmers, D.L.Kastner, “A genome-wide association study identifies new susceptibility loci for Behcet’s disease and epistasis between HLA-B*51 and ERAP1”, '''''Nature Genetics'''''45(2): 202-207, 2013.
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== '''Publications''' ==
 
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1. '''Yoonhee Kim''', Woongyang Park and Ho Kim, “An iterative normalization algorithm from cDNA microarray medical data analysis”, Genomics & Informatics, 2004, Vol.2 (2) 94-100.
 
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2. S.H. Lee, H.J. Bae, S.J. Kwon, H. Kim, '''Y.H. Kim''', B.W. Yoon, and J.K. Roh, “Cerebral microbleeds are regionally associated with intra cerebral hemorrhage”, NEUROLOGY, 2004, 62:72-76
+
K. C. Desch, A. B. Ozel, D. Siemieniak, Y. Kalish, C. Thornburg,  A. Sharathkumar, C. McHugh, C. Laurie, A. Crenshaw, D. Mirel, '''Y. Kim''', C. D. Cropp, A. M. Molloy,
 +
P. N. Kirke, J. E. Bailey-Wilson, A. F. Wilson, J. L. Mills, J. M. Scott, L. C. Brody, J. Z. Li and D. Ginsburg, “ Linkage Analysis Identifies a Novel Locus for Plasma von Willebrand
 +
Factor Undetected by Genome Wide Association”, doi:10.1073/pnas.1219885110,  '''''PNAS''''', 2012.
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3. S.H. Lee, J.M. Park, S.J. Kwon, H. Kim, '''Y.H. Kim''', J.K. Roh, and B.W. Yoon, “Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients”, NEUROLOGY,  2004. 63: 16-21.
 
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4. Sung J, Cho SI, Song YM, Lee K, Choi EY, Ha M, Kim J, Kim H, Kim Y, Shin EK, '''Kim YH''', Yoo KY, Park C, Kimm K, “Do we need more twin studies? The Healthy Twin Study, Korea”, Int J Epidemiol. 2006; 35(2):488-90.
+
C. M. Justice*, G. Yagnik*, '''Y. Kim''', I. Peter, E. W. Jabs, X. Ye, L. Shi, M.L. Cunningham, V. Kimonis, T. Roscioli, S. A. Wall, A. O.M. Wilkie, J. Stoler, J. T. Richtsmeier, Y. Heuze, P. A. Sanchez-Lara, M. F. Buckley, C. M. Druschel, J. L. Mills, M.Caggana, P. A. Romitti, D. M. Kay, C. Senders, P.J. Taub, O. D. Klein, J. Boggan, M. Zwienenberg-Lee, C. Naydenov, J. Kim,  A.F. Wilson, S. A. Boyadijiev, “A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9”, doi:10.1038/ng.2463 '''''Nature Genetics''''', 44, 1360-1364, 2012.
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5. '''Y. Kim''', B. Doan, P. Duggal, J. E. Bailey-Wilson, “Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis”, BMC Genetics Proceedings, 2007 I (Suppl 1) S152.
 
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6. '''Y. Kim''', P. Duggal, E.M. Gillanders, H. Kim, J.E. Bailey-Wilson, “Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data”, Genetic Epidemiology, 2008; 32:41-51.
+
 
 +
N. H. Miller, C. M. Justice, B. Marosy, K. Swindle,''' Y. Kim''', MH. Roy-Gagnon, H. Sung, D. Behneman, K. F. Doheny, E. Pugh, A .F. Wilson “Fine-mapping and family-based association tests of idiopathic scoliosis on 9q31.3-134.3 and 16p12.3-q22.2,” '''''Human Heredity''''', Vol 74, No. 1, 36-44, 2012.
 +
 
 +
 
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M. J. Emond, T. Louie, J. Emerson, W. Zhao, R. A. Mathias, M. R. Knowles, F. A. Wright, M. J. Rieder, H.K. Tabor, D.A. Nickerson, K.C. Barnes, NHLBI GO Exome Sequencing Project, Lung GO ('''Y. Kim'''), R.L. Gibson & M.J. Bamshad “Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis,” '''''Nature Genetics''''', Vol 44: 886–889, 2012.
 +
 
 +
 
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S. P. David, A. Hamidovic, G. K. Chen, A.W. Bergen, J. Wessel, J.L. Kasberger, W. M. Brown, S. Petruzella, E. L. Thacker, '''Y. Kim''', M.A. Nalls, G. J. Tranah, Y.J. Sung, AABC, AAPC, CHS, CARe, GeneSTAR, HANDLS, HealthABC, HyperGEN, WHI(SHARe), C.A. Haiman, H.Furberg, “Genome-wide meta-analyses of smoking behaviors in African Americans”, '''''Translational Psychiatry''''', 2:e119; doi:10.1038/tp.2012.41, 2012.
 +
 
 +
 
 +
'''Y. Kim'''*, Q. Li*, C.D. Cropp, H. Sung, J. Cai, C.L. Simpson, B.Perry, A.Dasgupta, J.D. Malley, A.F. Wilson, J.E. Bailey-Wilson “Performance of Random Forests and Logic Regression Methods Using Mini-Exome Sequence data,” '''''BMC proceedings''''', Vol 5 (supp 9):S104, 2011. PMID: 22373484 PMCID: PMC3287827
 +
 
 +
 
 +
J.E. Bailey-Wilson, J.S. Brennan, R. Culverhouse, '''Y. Kim''', Y. Jiang, J. Jung, Q. Li, C. Scholosberg, L. Wang, Y.E. Yilmaz, H. Zhang, Z. Zhan, “Regression and Data Mining Methods for Analyses of Multiple Rare Variants in GAW17 “ Mini-Exome” data,”  '''''Genetic Epidemiology''''', Vol 35(supp 1):S92-S100, 2011. PMID: 22128066 PMCID: PMC3360949
 +
 
 +
 
 +
H. Sung, '''Y. Kim''', J. Cai, C.D. Cropp, C.L. Simpson, Q. Li, B. C Perry,  A.J.M. Sorant, J.E. Bailey-Wilson, A.F. Wilson “A comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression,” '''''BMC proceedings''''', Vol 5(supp 9):S15, 2011. PMID: 22373501 PMCID: PMC3287849
 +
 
 +
 
 +
T.L. Assimes, H. Holm, ADVANCE, CATHGEN, GeneSTAR ('''Y. Kim'''), INTERHEART study groups, decode genetics, and T. Quertermous “Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies,” '''''Journal of the American College of Cardiology''''', Vol 56, No 19, 2010. PMID: 20933357 PMCID: PMC3084526
 +
 
 +
 
 +
R.A. Mathias*, '''Y. Kim'''*, H. Sung, R.Y. Yanek, J.E. Hererra-Galeano, I. Ruczinski, A.F. Wilson, N. Faraday, L.C. Becker, D.M. Becker “A Combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in Caucasian and African American families with coronary artery disease,” '''''BMC Medical Genomics''''', 3:22, 2010. PMID: 20529293 PMCID: PMC2890666
 +
 
 +
 
 +
'''Y. Kim''', R. Wojciechowski, H. Sung, R.A. Mathias, L. Wang, A.P. Klein, R.K. Lenroot, J. Malley, J.E. Bailey-Wilson, “Evaluation of random forests performance for genome wide association studies in the presence of interaction effects,” '''''BMC Proceedings''''', Vol3 (supp 7) s64, 2009. PMID: 20018058 PMCID: PMC2795965
 +
 
 +
 
 +
'''Y. Kim''', P. Duggal, E.M. Gillanders, H. Kim, J.E. Bailey-Wilson, “Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data,” '''''Genetic Epidemiology'''''; 32:41-51, 2008. PMID: 17685456 PMCID: PMC2216429
 +
 
 +
'''Y.Kim''', “Genetic epidemiology 101: A review of the statistical basis,” '''''BioWave''''' Vol. 10 (13):1, 2008.
 +
 
 +
 
 +
'''Y. Kim''', H. Kim. “Application of Random Forests to Association Studies Using Mitochondrial Single Nucleotide Polymorphisms,” '''''Genomics & Informatics''''' Vol. 5 (4) 168-173, 2007.
 +
 
 +
 
 +
'''Y. Kim''', B. Doan, P. Duggal, J. E. Bailey-Wilson, “Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis,” '''''BMC Genetics Proceedings''''', I (Supp 1) S152, 2007.
 +
 
 +
 
 +
Sung J, Cho SI, Song YM, Lee K, Choi EY, Ha M, Kim J, Kim H, Kim Y, Shin EK, Kim YH, Yoo KY, Park C, Kimm K, “Do we need more twin studies? The Healthy Twin Study, Korea,” '''''Int J Epidemiology''''', 35(2):488-90, 2006.
 +
 
 +
 
 +
S.H. Lee, J.M. Park, S.J. Kwon, H. Kim, '''Y.H. Kim''', J.K. Roh, and B.W. Yoon, “Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients,” '''''Neurology''''', 63: 16-21, 2004.
 +
 
 +
 
 +
S.H. Lee, H.J. Bae, S.J. Kwon, H. Kim, '''Y.H. Kim''', B.W. Yoon, and J.K. Roh, “Cerebral microbleeds are regionally associated with intra cerebral hemorrhage,”  '''''Neurology''''', 62:72-76, 2004.
 +
 
 +
 
 +
'''Y. Kim''', W. Park, H. Kim, “An iterative normalization algorithm from cDNA microarray medical data analysis,” '''''Genomics & Informatics''''', Vol.2 (2) 94-100, 2004.

Current revision

Contents

Yoonhee Kim, M.P.H, Ph.D.

Division of Clinical Pharmacology Office of Translational Sciences Center for Drug Evaluation and Research U.S. Food and Drug Administration 10903 New Hampshire Ave., Bldg 51 Room 2135 Silver Spring, MD 20993-0002

Email: Yoonhee.kim@fda.hhs.gov

RESEARCH INTEREST

Statistical Genetics, Genetic Epidemiology, Clinical trials,

Next Generation Sequencing data analysis, GenexGene Interaction analysis using Machine Learning Methods (Random Forests)

EDUCATION

2008 Ph.D. in Epidemiology and Biostatistics, Seoul National University, School of Public Health, Korea

2003 M.P.H in Epidemiology and Biostatistics, Seoul National University, School of Public Health, Korea

2001 B.S. in Statistics and Biology (double majors) Ewha Womans Univerisity, Korea

EMPLOYMENT

2008-2012 Research Fellow (Statistical geneticist), National Human Genome Research Institute, National Institutes of Health, USA

2005-2008 Visiting Fellow, Predoctoral trainee, National Human Genome Research Institute, National Institutes of Health, USA

PUBLICATION

23 manuscripts published (* co-first author)


Y. Kim, B. Suktitipat, L. R. Yanek, N. Faraday, A.F. Wilson, D.M. Becker, L.C. Becker, R.A. Mathias, “Targeted deep re-sequencing identifies coding variants in the PEAR1 gene that play a role in platelet aggregation”, in press PLoS One, 2013.


Y. Kirino, Q. Zhou, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, S. Ugurlu, B. Eror, N. Abaci, D. Ustek, A. Meguro, A. Ueda, M. Takeno, H. Inoko, M. J. Ombrello, C. Satorius, B. Maskeri, J. C. Mullikin, H-W Sun, G. Gutierrez-Cruz, Y. Kim, A. F. Wilson, D. L. Kastner, A. Gul, E. F. Remmers, “Targeted deep re-sequencing implicates the familial Mediterranean fever gene MEFV and the bacterial sensor TLR4 in Behcet’s disease”, in press PNAS, 2013.


N. N. Hansel, I. Ruczinski, N. Rafaels, D. D. Sin, D. Daley, A. Malinina, L. Huang, A. Sandford, M. Elliott, T. Murray, Y. Kim, C. Vergara, S. R. Heckbert, B. M. Psaty, G. Li, F. Aminuddin, J. Dupuis, G. O’Connor, M. Boezen, D.S.Postma, J.Smolonska, R. Crystal, T. Toshiko, L. Ferruci, E. Silverman, E. Wan, J. Vestbo, D. Lomas, J. Connett, R. A. Wise, E.R. Neptune, R. Mathias, P.D. Pare, T. H. Beaty, K. C. Barnes “Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD,” Human Genetics, 132(1):79-90, 2013.


Y. Kirino, G. Bertsias, Y. Ishigatsubo, N. Mizuki, I. Tugal-Tutkun, E. Seyahi, Y. Ozyazgan, F. S.Sacli, B. Erer, Z. Emrence, A. Cakar, D. Ustek, C. Satorius, A. Ueda, M. Takeno, Y. Kim, M. J. Ombrello, A. Meguro, A. Gul, E.F. Remmers, D.L.Kastner, “A genome-wide association study identifies new susceptibility loci for Behcet’s disease and epistasis between HLA-B*51 and ERAP1”, Nature Genetics45(2): 202-207, 2013.


K. C. Desch, A. B. Ozel, D. Siemieniak, Y. Kalish, C. Thornburg, A. Sharathkumar, C. McHugh, C. Laurie, A. Crenshaw, D. Mirel, Y. Kim, C. D. Cropp, A. M. Molloy, P. N. Kirke, J. E. Bailey-Wilson, A. F. Wilson, J. L. Mills, J. M. Scott, L. C. Brody, J. Z. Li and D. Ginsburg, “ Linkage Analysis Identifies a Novel Locus for Plasma von Willebrand Factor Undetected by Genome Wide Association”, doi:10.1073/pnas.1219885110, PNAS, 2012.


C. M. Justice*, G. Yagnik*, Y. Kim, I. Peter, E. W. Jabs, X. Ye, L. Shi, M.L. Cunningham, V. Kimonis, T. Roscioli, S. A. Wall, A. O.M. Wilkie, J. Stoler, J. T. Richtsmeier, Y. Heuze, P. A. Sanchez-Lara, M. F. Buckley, C. M. Druschel, J. L. Mills, M.Caggana, P. A. Romitti, D. M. Kay, C. Senders, P.J. Taub, O. D. Klein, J. Boggan, M. Zwienenberg-Lee, C. Naydenov, J. Kim, A.F. Wilson, S. A. Boyadijiev, “A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9”, doi:10.1038/ng.2463 Nature Genetics, 44, 1360-1364, 2012.


N. H. Miller, C. M. Justice, B. Marosy, K. Swindle, Y. Kim, MH. Roy-Gagnon, H. Sung, D. Behneman, K. F. Doheny, E. Pugh, A .F. Wilson “Fine-mapping and family-based association tests of idiopathic scoliosis on 9q31.3-134.3 and 16p12.3-q22.2,” Human Heredity, Vol 74, No. 1, 36-44, 2012.


M. J. Emond, T. Louie, J. Emerson, W. Zhao, R. A. Mathias, M. R. Knowles, F. A. Wright, M. J. Rieder, H.K. Tabor, D.A. Nickerson, K.C. Barnes, NHLBI GO Exome Sequencing Project, Lung GO (Y. Kim), R.L. Gibson & M.J. Bamshad “Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis,” Nature Genetics, Vol 44: 886–889, 2012.


S. P. David, A. Hamidovic, G. K. Chen, A.W. Bergen, J. Wessel, J.L. Kasberger, W. M. Brown, S. Petruzella, E. L. Thacker, Y. Kim, M.A. Nalls, G. J. Tranah, Y.J. Sung, AABC, AAPC, CHS, CARe, GeneSTAR, HANDLS, HealthABC, HyperGEN, WHI(SHARe), C.A. Haiman, H.Furberg, “Genome-wide meta-analyses of smoking behaviors in African Americans”, Translational Psychiatry, 2:e119; doi:10.1038/tp.2012.41, 2012.


Y. Kim*, Q. Li*, C.D. Cropp, H. Sung, J. Cai, C.L. Simpson, B.Perry, A.Dasgupta, J.D. Malley, A.F. Wilson, J.E. Bailey-Wilson “Performance of Random Forests and Logic Regression Methods Using Mini-Exome Sequence data,” BMC proceedings, Vol 5 (supp 9):S104, 2011. PMID: 22373484 PMCID: PMC3287827


J.E. Bailey-Wilson, J.S. Brennan, R. Culverhouse, Y. Kim, Y. Jiang, J. Jung, Q. Li, C. Scholosberg, L. Wang, Y.E. Yilmaz, H. Zhang, Z. Zhan, “Regression and Data Mining Methods for Analyses of Multiple Rare Variants in GAW17 “ Mini-Exome” data,” Genetic Epidemiology, Vol 35(supp 1):S92-S100, 2011. PMID: 22128066 PMCID: PMC3360949


H. Sung, Y. Kim, J. Cai, C.D. Cropp, C.L. Simpson, Q. Li, B. C Perry, A.J.M. Sorant, J.E. Bailey-Wilson, A.F. Wilson “A comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression,” BMC proceedings, Vol 5(supp 9):S15, 2011. PMID: 22373501 PMCID: PMC3287849


T.L. Assimes, H. Holm, ADVANCE, CATHGEN, GeneSTAR (Y. Kim), INTERHEART study groups, decode genetics, and T. Quertermous “Lack of association between the Trp719Arg polymorphism in kinesin-like protein 6 and coronary artery disease in 19 case-control studies,” Journal of the American College of Cardiology, Vol 56, No 19, 2010. PMID: 20933357 PMCID: PMC3084526


R.A. Mathias*, Y. Kim*, H. Sung, R.Y. Yanek, J.E. Hererra-Galeano, I. Ruczinski, A.F. Wilson, N. Faraday, L.C. Becker, D.M. Becker “A Combined genome-wide linkage and association approach to find susceptibility loci for platelet function phenotypes in Caucasian and African American families with coronary artery disease,” BMC Medical Genomics, 3:22, 2010. PMID: 20529293 PMCID: PMC2890666


Y. Kim, R. Wojciechowski, H. Sung, R.A. Mathias, L. Wang, A.P. Klein, R.K. Lenroot, J. Malley, J.E. Bailey-Wilson, “Evaluation of random forests performance for genome wide association studies in the presence of interaction effects,” BMC Proceedings, Vol3 (supp 7) s64, 2009. PMID: 20018058 PMCID: PMC2795965


Y. Kim, P. Duggal, E.M. Gillanders, H. Kim, J.E. Bailey-Wilson, “Examining the effect of linkage disequilibrium between markers on the Type I error rate and power of nonparametric multipoint linkage analysis of two-generation and multigenerational pedigrees in the presence of missing genotype data,” Genetic Epidemiology; 32:41-51, 2008. PMID: 17685456 PMCID: PMC2216429

Y.Kim, “Genetic epidemiology 101: A review of the statistical basis,” BioWave Vol. 10 (13):1, 2008.


Y. Kim, H. Kim. “Application of Random Forests to Association Studies Using Mitochondrial Single Nucleotide Polymorphisms,” Genomics & Informatics Vol. 5 (4) 168-173, 2007.


Y. Kim, B. Doan, P. Duggal, J. E. Bailey-Wilson, “Normalization of microarray expression data using within-pedigree pool and its effect on linkage analysis,” BMC Genetics Proceedings, I (Supp 1) S152, 2007.


Sung J, Cho SI, Song YM, Lee K, Choi EY, Ha M, Kim J, Kim H, Kim Y, Shin EK, Kim YH, Yoo KY, Park C, Kimm K, “Do we need more twin studies? The Healthy Twin Study, Korea,” Int J Epidemiology, 35(2):488-90, 2006.


S.H. Lee, J.M. Park, S.J. Kwon, H. Kim, Y.H. Kim, J.K. Roh, and B.W. Yoon, “Left ventricular hypertrophy is associated with cerebral microbleeds in hypertensive patients,” Neurology, 63: 16-21, 2004.


S.H. Lee, H.J. Bae, S.J. Kwon, H. Kim, Y.H. Kim, B.W. Yoon, and J.K. Roh, “Cerebral microbleeds are regionally associated with intra cerebral hemorrhage,” Neurology, 62:72-76, 2004.


Y. Kim, W. Park, H. Kim, “An iterative normalization algorithm from cDNA microarray medical data analysis,” Genomics & Informatics, Vol.2 (2) 94-100, 2004.

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