CH391L/S13

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(New page: Category:CH391L_S13 ==CH391L: Molecular Mechanisms of Genome Maintenance== Spring 2013 Instructor: Dr. Jeffrey Barrick <jbarrick AT cm DOT utexas PERIOD edu> Course web page: The ...)
(Replacing page with 'Category:CH391L_S13 ==CH391L: Molecular Mechanisms of Genome Maintenance== Spring 2013 Instructor: Dr. Ilya Finkelstein Stay tuned for additional information')
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Instructor: Dr. Jeffrey Barrick <jbarrick AT cm DOT utexas PERIOD edu>
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Instructor: Dr. Ilya Finkelstein
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Course web page: The course web site on OpenWetWare.org http://openwetware.org/wiki/CH391L/S12 will host course handouts, readings, and assignments.
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Stay tuned for additional information
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[[Media:CH391L_S12_Syllabus.pdf | Course Syllabus (PDF) ]]
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[http://2012.igem.org/Main_Page 2012 iGEM Competition]
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[[CH391L/S12/Users | CH391L Users]]
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== Motivation ==
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The purpose of this course is to become familiar with the techniques, biological parts, accomplishments, problems, and challenges of synthetic biology. For the most part, we will focus on ''E. coli'' and yeast. Participants will be expected to individually contribute to OWW pages describing the history, development, and implementation details of engineered parts and organisms from the scientific literature. Then, they will be expected to create a proposal as part of a group with specific experimental and modeling details for using synthetic biology to solve an outstanding problem with technological or societal impact.
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== Assignments ==
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Coursework will consist of in-class oral presentations on scientific papers or research proposals and a "written" component consisting of Wiki page edits on OpenWetWare. All participants in the course will be expected to provide feedback concerning the content of presentations and the content of Wiki pages.
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[[CH391L/S12/WikiEditing|Instructions for Wiki Editing]]
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[[CH391L/S12/Assignments|Class Assignments]]
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[[CH391L/S12/TopicGradingRubric|Grading Rubric for Topic Pages and Presentations]]
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[[CH391L/S12/FinalProjectRubric|Grading Rubric for Final Project]]
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==Synthetic Biology Seminars at UT==
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===Upcoming===
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===Past===
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*Frances Arnold (Caltech) Gottlieb Lecture - Friday, Mar 2, 2:00 PM,  ACE 2.302 [http://cheme.che.caltech.edu/groups/fha/ webpage]
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*Frank M Raushel (Texas A&M University) - Friday, Feb 17th, 1:30pm, WEL 2.122 [http://www.chem.tamu.edu/faculty/faculty_detail.php?ID=65/ webpage]
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*Roger Tsien (UCSD) Burdette Lecture, 2008 Nobel Prize in Chemistry - Tuesday, Feb 7, 2:30 PM, SAC 1.402 [http://www.tsienlab.ucsd.edu/ webpage]
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*Douglas Fowler (U Washington) - Monday, Feb 6, 3:30 PM, WEL 2.122 [http://depts.washington.edu/sfields/staff.html webpage]
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*Michelle Chang (UC Berkeley) - Friday, Feb 3, 3:30 PM, WEL 2.122 [http://chem.berkeley.edu/faculty/chang_m/ webpage]
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*Erik Winfree (Caltech) - Thursday, Feb 2, 3:30 PM, ACES 6.304 [http://www.dna.caltech.edu/~winfree/ webpage]
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*Lulu Qian (Caltech) - Wednesday, Feb. 1 4:00 PM, WEL 2.122 [http://dna.caltech.edu/~lulu/ webpage]
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*Sang Yup Lee (Korea Advanced Institute of Science and Technology (KAIST)) - Tuesday, Jan. 31 3:30pm, CPE 2.218 [http://www.che.utexas.edu/event/pirkey-systems-metabolic-engineering-of-microorganisms-for-chemicals-fuels-and-materials-by-dr-sang-yup-lee-korea-advanced-institute-of-science-and-technology-kaist/ webpage]
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==Synthetic Biology News==
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Here is a [[CH391L/S12/RecentNews | collection of recent news articles]] related to current synthetic biology. Please feel free to add anything you feel is relevant to the class and any appropriate comments or descriptions.
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== Topics ==
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===Introduction===
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[[:Category:CH391L_S12 | Index of All CH391/S12 Pages]]
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[[Special:RecentChangesLinked/Category:CH391L_S12 | View Recent Changes to CH391/S12 Pages]]
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==== Week 1: Introduction ====
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* [[CH391L/S12/Introduction | Introduction to synthetic biology]]
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===Methods===
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====Week 2: Making or finding parts====
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* [[CH391L/S12/iGEM Registry | iGEM Registry]]
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* [[CH391L/S12/Bioprospecting | Bioprospecting new parts using Metagenomics]]
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* [[CH391L/S12/In vitro Selection | ''In vitro'' selection]]
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* [[/CH391L/S12/Ancestral Sequence Reconstruction | Ancestral Sequence Reconstruction]]
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====Week 3: Assembling parts into systems====
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* [[CH391L/S12/Restriction_enzymes_and_BioBricks_assembly_standards | Restriction enzymes and BioBricks/BglBricks assembly standards (RFCs)]]
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* [[CH391L/S12/PCR and advanced PCR techniques | PCR and advanced PCR techniques]]
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====Week 4: Parts assembly, metabolic engineering, and choosing a chassis====
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* [[CH391L/S12/GeneandGenomeSynthesis | Gene and genome synthesis]]
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* [[CH391L/S12/MetabolicEngineering | Metabolic Engineering]]
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* [[CH391L/S12/HostOrganisms | Chassis (Host organisms)]]
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=== Parts ===
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====Week 5: Chassis and Backbones====
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* [[CH391L/S12/Selectablegeneticmarkers | Selectable genetic markers]]
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* [[CH391L/S12/ToxinAntitoxins | Toxin/anti-toxins, plasmid addiction systems]]
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* [[CH391L/S12/CounterSelection| Counter-selectable genetic markers]]
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====Week 6: Basic Gene Construction====
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* [[CH391L/S12/TranslationRBSandCodons | Ribosome Binding Sites and Codon Optimization]]
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* [[CH391L/S12/TranscriptionPromotersandTerminators | Transcriptional Promoters and Terminators]]
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* [[CH391L/S12/SpinachRNA | Spinach Aptamer]]
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====Week 7: Gene regulation ====
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* [[CH391L/S12/Origins of Replication | Origins of Replication]]
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* [[CH391L/S12/LightSensors | Light Sensors]]
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* [[CH391L/S12/Protein_regulators_of_transcription | Protein regulators of transcription]]
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====Week 8: Reporter Genes====
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* [[CH391L/S12/Pigments | Pigments]]
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* [[CH391L/S12/Fluorescent Proteins | Fluorescent Proteins]]
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====Week 9:  Complex parts====
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* [[CH391L/S12/Unnatural_Amino_Acids | Unnatural Amino Acid Incorporation]]
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* [[CH391L/S12/Locomotion | Locomotion]]
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* [[CH391L/S12/Quorum_Sensing | Quorum Sensing]]
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===Systems===
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====Week 10: Systems I====
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*[[CH391L/S12/Pattern Formation | Pattern Formation]]
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*[[CH391L/S12/Toggle Switches, Repressilators, and Counters | Toggle Switches, Repressilators, and Counters]]
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*[[CH391L/S12/Refactoring Genomes | Refactoring Genomes]]
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====Week 11: Systems II====
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*[[CH391L/S12/Artemisinic Acid Engineering | Artemisinic Acid Engineering ]]
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*[[CH391L/S12/Synthetic Cooperation | Synthetic Cooperation ]]
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*[[CH391L/S12/MAGE lycopene production, CAGE "Amberless" E. coli | MAGE lycopene production, CAGE "Amberless" E. coli ]]
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====Week 12: Systems III====
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*[[CH391L/S12/Bacterial Odor Engineering | Bacterial Odor Engineering ]]
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Revision as of 19:54, 13 November 2012


CH391L: Molecular Mechanisms of Genome Maintenance

Spring 2013


Instructor: Dr. Ilya Finkelstein

Stay tuned for additional information

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