CH391L/S13/Topics

From OpenWetWare

This is a brainstorming page...

Contents 1 What is synthetic biology? 1.1 Videos 2 Recent/Upcoming Meetings 3 New Topics 3.1 Algal biofuels 3.2 DNA computation / nanomachines 3.3 Spider Goats 3.4 Pathogen synthesis 3.5 Riboswitches / Aptamer Biosensors 3.6 Gene Therapy 3.7 Spermless Mosquitos Mate without Offspring 3.8 Mussel bioadhesives 3.9 Dental Probiotics 4 Topic Updates 4.1 Refactoring 4.2 Ancestral Sequence Reconstruction 5 Other 5.1 Humor 5.2 Software 5.3 Other synthetic biology courses 5.4 Notable iGEM Projects

What is synthetic biology?

http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0034368

http://www.buzzfeed.com/atmccann/how-to-code-a-life

Videos

Imperial College iGEM team documentary (50 min) http://www.youtube.com/watch?v=ushmgPM7HT8

E. chromi http://vimeo.com/19759432

Recent/Upcoming Meetings

http://www.keystonesymposia.org/index.cfm?e=web.Meeting.Program&meetingid=1238

http://sb6.biobricks.org/

New Topics

Algal biofuels

http://joulefuels.com/how-it-works

DNA computation / nanomachines

1. Langecker M, Arnaut V, Martin TG, List J, Renner S, Mayer M, Dietz H, and Simmel FC. . pmid:23161995. PubMed HubMed [Langecker]

   DNA origami to design functional structures

Spider Goats

"Spider Goats" - synthetic silk production. Video - http://www.fieldtest.us/bio.shtml

Pathogen synthesis

2. Cello J, Paul AV, and Wimmer E. . pmid:12114528. PubMed HubMed [Cello2002]

   Polio virus

3. Herfst S, Schrauwen EJ, Linster M, Chutinimitkul S, de Wit E, Munster VJ, Sorrell EM, Bestebroer TM, Burke DF, Smith DJ, Rimmelzwaan GF, Osterhaus AD, and Fouchier RA. . pmid:22723413. PubMed HubMed [Herfst2012]

   AIrborne H5N1

4. Russell CA, Fonville JM, Brown AE, Burke DF, Smith DL, James SL, Herfst S, van Boheemen S, Linster M, Schrauwen EJ, Katzelnick L, Mosterín A, Kuiken T, Maher E, Neumann G, Osterhaus AD, Kawaoka Y, Fouchier RA, and Smith DJ. . pmid:22723414. PubMed HubMed [Russell2012]

   AIrborne H5N1

All Medline abstracts: PubMed HubMed

Airborne H5N1 publication debate http://www.nytimes.com/2011/12/27/science/debate-persists-on-deadly-flu-made-airborne.html?pagewanted=all&_r=0 http://www.sciencemag.org/content/336/6088/1521.full

Riboswitches / Aptamer Biosensors

4. Davidson ME, Harbaugh SV, Chushak YG, Stone MO, and Kelley-Loughnane N. . pmid:23092157. PubMed HubMed [Russell2012]

   DNT/TNT riboswitch

5. Ehrentreich-Förster E, Orgel D, Krause-Griep A, Cech B, Erdmann VA, Bier F, Scheller FW, and Rimmele M. . pmid:18504560. PubMed HubMed [Ehrentreich2008]

   TNT aptamer

6. Stojanovic MN, de Prada P, and Landry DW. . pmid:11457319. PubMed HubMed [Stojanovic2001]

   Cocaine aptamer biosensor

7. Stojanovic MN and Landry DW. . pmid:12175205. PubMed HubMed [Stojanovic2002]

   Cocaine aptamer biosensor, next iteration

All Medline abstracts: PubMed HubMed

Gene Therapy

Spermless Mosquitos Mate without Offspring

8. Thailayil J, Magnusson K, Godfray HC, Crisanti A, and Catteruccia F. . pmid:21825136. PubMed HubMed [Thailayil2011]

Mussel bioadhesives

http://techportal.eere.energy.gov/technology.do/techID=562

Dental Probiotics

Topic Updates

Refactoring

9. Temme K, Zhao D, and Voigt CA. . pmid:22509035. PubMed HubMed [Temme2012]

   Refactoring Nitrogen fixation gene cluster

Ancestral Sequence Reconstruction

http://fastml.tau.ac.il/

Other

Humor

https://www.facebook.com/IgemMemes

Software

Other synthetic biology courses

http://soslab.ee.washington.edu/synthbio/index.php/Main_Page

Notable iGEM Projects