CH391L/S2013/SuggestedTopics: Difference between revisions
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= Topics = | |||
Us this page to brainstorm or suggest possible topics and ideas | |||
Topic choices should be discussed with the instructor at least '''one week''' prior to the scheduled presentation. A list of topics can be found below, but there is significant leeway to tailor the papers and topics toward your specific interests. | |||
== Double Strand Break (DSB) Repair == | == Double Strand Break (DSB) Repair == | ||
| Line 77: | Line 74: | ||
== p53 -- The Guardian of the Genome == | == p53 -- The Guardian of the Genome == | ||
Latest revision as of 22:46, 15 January 2013
Topics
Us this page to brainstorm or suggest possible topics and ideas
Topic choices should be discussed with the instructor at least one week prior to the scheduled presentation. A list of topics can be found below, but there is significant leeway to tailor the papers and topics toward your specific interests.
Double Strand Break (DSB) Repair
- DSB repair mechanisms in prokaryotes
- Homologous Recombination
- SOS Response
- DSB repair in eukaryotes
- Homologous Recombination
- Non-Homologous End Joining
- Alternative End-Joining
- DSB Repair: Pathway Choice
- DSB-related diseases:
- Seckel & Jawad Syndromes
- Nijmegen Breakage Syndrome
- Ataxia - telangiectasia
- Werner & Bloom Syndromes
DNA Replication and Genomic Instability
- Replicating Aberrant Structures
- DNA Hairpins
- Z-DNA
- G-Quadruplex DNA
- Chromosome Fragile Sites
- Replication-Transcription Conflicts
- Replication-Collapse at Interstrand Cross Links
Mechanisms of DNA Mismatch Repair
- Mismatch Repair in Prokaryotes
- Very short patch repair
- Mismatch Repair in Eukaryotes
- How is a Mismatch Recognized?
- How is a Mismatch Removed?
- Mismatch repair and adaptation
- Mutagenesis in Bacteria
- Mutagenesis in Eukaryotes
- Meiotic-specific Roles of Mismatch Repair Proteins
- Diseases
- Lynch Syndrome
Mitochondrial DNA Damage
- Structure of Mitochondrial DNA
- Mechanisms of DNA Repair
- Mitochondrial DNA repair and aging
- Diseases Associated with Mitochondrial DNA Damage
Nucleotide Excision Repair
Base Excision Repair
Damage Tolerance and Mutagenesis
- Prokaryotes
- Error-prone translesion synthesis
- Living with chronic damage
- Eukaryotes
- Error-prone translesion synthesis
- Living with chronic damage
Cell-cycle response to DNA damage
Systems approaches to cancer research
- Global analysis of transcription changes
- Global analysis of siRNA changes in cancer cells
