CH391L/S2013 Logan Myler March 27 2013

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Contents

Background

Methods

Results

Figure 2: Mobility of MutSa on mismatch containing DNA
Figure 2: Mobility of MutSa on mismatch containing DNA

Significance

This paper, along with the author's previous works(x,y), not only describes the movement of the mismatch repair proteins along DNA, but also gives a model by which the cell can selectively find DNA damage.

References

  1. Gorman, J. et al., "Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair". Proc. Natl. Acad. Sci. 2012.
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