CHE.496/2008

Course Overview

This course was designed by an undergraduate student at the University of Virginia to facilitate a constructive learning environment for undergraduate students interested in synthetic biology. The main goal of this course is to introduce the engineering principles and tools necessary to design, model and build a functional biological system and, in doing so, program novel cellular function and behavior to solve engineering problems and test biological hypotheses.

Synthetic biology is emerging as a new engineering discipline, applying engineering principles such as the standardization of modular components, the hierarchical abstraction of complex systems, and the characterization of both components and systems to biology, allowing the decoupling of construction from design. Novel biological systems may be engineered to solve industrial, medical and environmental engineering problems such as the bioremediation of toxic waste, the microbial production of the anti-malarial drug artemisinin, and the biosynthesis of hydrogen or butanol as an alternative fuel source,

Course coordinator: Professor Erik Fernandez
Meeting times: W 6-6:50pm, R 7-7:50pm
Questions? Contact George McArthur

Expectations

• Attendance
• Read material for each meeting
• Write a response to each reading assignment
• Lead discussions (rotational basis)
• Complete 3 main projects

News

• Final project designs.

Recent Updates

List of abbreviations:

N

This edit created a new page (also see list of new pages)

m

This is a minor edit

b

This edit was performed by a bot

(±123)

The page size changed by this number of bytes

18 April 2024

15:01

Pan:Who we are‎ diffhist +14‎ Taopan talk contribs

			15:00		Pan:Methods‎‎ 2 changes history +456‎ [Taopan‎ (2×)]
					15:00 (cur | prev) +2‎ Taopan talk contribs
					14:59 (cur | prev) +454‎ Taopan talk contribs

			14:56		Pan:Publications‎‎ 2 changes history +396‎ [Taopan‎ (2×)]
					14:56 (cur | prev) +74‎ Taopan talk contribs
					14:54 (cur | prev) +322‎ Taopan talk contribs

13:03

BioMicroCenter:Pricing‎ diffhist +166‎ Challee talk contribs

			12:58		BioMicroCenter:Singular Sequencing‎‎ 2 changes history +124‎ [Challee‎ (2×)]
					12:58 (cur | prev) +14‎ Challee talk contribs (→‎Things to Consider)
					12:57 (cur | prev) +110‎ Challee talk contribs

11:42

3D Cell Culture - McLean Taggart, Emma Villares, Maximillian Marek, Scott LeBlanc, Adam Lyons and Jacob Belden‎ diffhist −3‎ Sarah L. Perry talk contribs

			09:35		BioMicroCenter‎‎ 2 changes history +92‎ [Noelani Kamelamela‎ (2×)]
					09:35 (cur | prev) +60‎ Noelani Kamelamela talk contribs
					09:20 (cur | prev) +32‎ Noelani Kamelamela talk contribs

09:32

Upload log Noelani Kamelamela talk contribs uploaded File:Chemagic360.jpg ‎(from manual)

17 April 2024

			15:34		BioMicroCenter:Element Sequencing‎‎ 3 changes history +295‎ [Challee‎ (3×)]
					15:34 (cur | prev) +195‎ Challee talk contribs
					14:22 (cur | prev) +100‎ Challee talk contribs
					14:07 (cur | prev) 0‎ Challee talk contribs

13:10

BioMicroCenter:SingleCell‎ diffhist +30‎ Noelani Kamelamela talk contribs (→‎10X CHROMIUM X)

12:43

BioMicroCenter‎ diffhist −15‎ Noelani Kamelamela talk contribs

16 April 2024

			N    19:59		Nanoimprint Lithography (NIL) - Carter Paul‎‎ 10 changes history +7,205‎ [CarterPaul‎ (10×)]
					19:59 (cur | prev) +769‎ CarterPaul talk contribs (→‎Thermal NIL Process)
					19:53 (cur | prev) 0‎ CarterPaul talk contribs (→‎Thermal NIL Process)
					19:53 (cur | prev) 0‎ CarterPaul talk contribs (→‎Thermal NIL Process)
					19:52 (cur | prev) +1‎ CarterPaul talk contribs (→‎Thermal NIL Process)
					19:50 (cur | prev) +202‎ CarterPaul talk contribs (→‎Thermal NIL Process)
					19:17 (cur | prev) −20‎ CarterPaul talk contribs (→‎References)
					19:17 (cur | prev) −1‎ CarterPaul talk contribs
					19:11 (cur | prev) +4,278‎ CarterPaul talk contribs
					18:53 (cur | prev) +1,891‎ CarterPaul talk contribs
			N		18:42 (cur | prev) +85‎ CarterPaul talk contribs (Created page with "{{Template:CHEM-ENG590E}} =Motivation= =Introduction to NIL= =Thermal NIL Process=")

19:40

Upload log CarterPaul talk contribs uploaded File:NIL1.png ‎

N    18:40

3D Cell Culture - McLean Taggart, Emma Villares, Maximillian Marek, Scott LeBlanc, Adam Lyons and Jacob Belden‎ diffhist +24,060‎ CarterPaul talk contribs (Created page with "{{Template:CHEM-ENG590E}} ==Introduction== While most microfluidic devices incorporate a 2D cell culture design, in which a single layer of cells is grown on the bottom of a device, these systems suffer from poor <i>in vivo</i> mimicry, as, in the human body, most cells grow in all directions.<sup>https://doi.org/10.5114/aoms.2016.63743 1</sup> To address this limitation, 3D cell culture devices have been developed - in w...")

			18:38		CHEM-ENG590E:Wiki Textbook‎‎ 2 changes history +63‎ [CarterPaul‎ (2×)]
					18:38 (cur | prev) +50‎ CarterPaul talk contribs (→‎Chapter 1 - Microfabrication)
					18:37 (cur | prev) +13‎ CarterPaul talk contribs

18:36

3D Cell Culture - McLean Taggart, Emma Villares, Maximillian Marek, Scott LeBlanc, and Adam Lyons‎ diffhist +5,343‎ CarterPaul talk contribs (Added a Technique and applications section)

			10:20		Yarn Microfluidics - Roger Dirth‎‎ 11 changes history +406‎ [Rcostello‎ (11×)]
					10:20 (cur | prev) +41‎ Rcostello talk contribs (→‎Applications)
					10:19 (cur | prev) +36‎ Rcostello talk contribs (→‎Applications)
					10:18 (cur | prev) +36‎ Rcostello talk contribs (→‎Introduction)
					10:17 (cur | prev) +38‎ Rcostello talk contribs (→‎Fabrication)
					10:17 (cur | prev) +38‎ Rcostello talk contribs (→‎Washburn Equation)
					10:16 (cur | prev) +38‎ Rcostello talk contribs (→‎Wicking Rate)
					10:16 (cur | prev) +37‎ Rcostello talk contribs (→‎Introduction)
					10:15 (cur | prev) +36‎ Rcostello talk contribs (→‎Wicking Rate)
					10:14 (cur | prev) +36‎ Rcostello talk contribs (→‎Fabrication)
					10:14 (cur | prev) +34‎ Rcostello talk contribs (→‎Applications)
					10:14 (cur | prev) +36‎ Rcostello talk contribs (→‎Introduction)