CHE.496/2008/Assignments
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====Assignment 10: Minimal genomes==== | ====Assignment 10: Minimal genomes==== | ||
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| - | # '''Essential genes of a minimal bacterium | + | # '''Essential genes of a minimal bacterium [http://lib.bioinfo.pl/pmid:16407165 link] |
| - | # '''Leaner and meaner genomes in ''E. coli'' | + | # '''Leaner and meaner genomes in ''E. coli'' [http://genomebiology.com/2006/7/10/237 link] |
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====Assignment 11: Minimal cells==== | ====Assignment 11: Minimal cells==== | ||
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| - | # '''Toward synthesis of a minimal cell | + | # '''Toward synthesis of a minimal cell [http://www.nature.com/msb/journal/v2/n1/full/msb4100090.html link] |
| - | # '''Rebuilding microbial genomes | + | # '''Rebuilding microbial genomes [http://www3.interscience.wiley.com/cgi-bin/abstract/114264051/ABSTRACT?CRETRY=1&SRETRY=0 link] |
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====Assignment 12: Genetic circuit engineering==== | ====Assignment 12: Genetic circuit engineering==== | ||
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# '''Environmentally controlled invasion of cancer cells by engineered bacteria [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WK7-4HJRXGD-4&_user=709071&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000039638&_version=1&_urlVersion=0&_userid=709071&md5=cac1dbad4022f85af3724a9ba787d3dd link] | # '''Environmentally controlled invasion of cancer cells by engineered bacteria [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WK7-4HJRXGD-4&_user=709071&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000039638&_version=1&_urlVersion=0&_userid=709071&md5=cac1dbad4022f85af3724a9ba787d3dd link] | ||
| - | # '''Environmental signal integration by a modular AND gate | + | # '''Environmental signal integration by a modular AND gate [http://www.nature.com/msb/journal/v3/n1/synopsis/msb4100173.html link] |
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====Assignment 14: Metabolic pathway engineering==== | ====Assignment 14: Metabolic pathway engineering==== | ||
Revision as of 15:03, 3 January 2008
Assigned Readings
Assignment 1: Synthetic biology overview
Assignment 2: Foundational technologies
Assignment 3: Engineering principles
- Synthetic biology - putting engineering into biology link
- Synthetic biology: new engineering rules for an emerging discipline link
Assignment 4: Genetic programming
- Idempotent vector design for standard assembly of biobricks link
- Genetic parts to program bacteria link
Assignment 5: Natural biological parts
- Another side of genomics: Synthetic biology as a means for the exploitation of whole-genome sequence information link
- Codon bias and heterologous protein expression link
Assignment 6: Practical applications
- Advances in synthetic biology: on the path from prototypes to applications link
- Molecular switches for cellular sensors link
Assignment 7: Social implications
Assignment 8: Engineering biology
Assignment 9: Biological machines
- Designing biological systems link
- Biology by design: Reduction and synthesis of cellular components and behavior link
Assignment 10: Minimal genomes
Assignment 11: Minimal cells
Assignment 12: Genetic circuit engineering
- A synthetic oscillatory network of transcriptional regulators link
- Construction of a genetic toggle switch in Escherichia coli link
Assignment 13: Genetic circuit engineering
- Environmentally controlled invasion of cancer cells by engineered bacteria link
- Environmental signal integration by a modular AND gate link
Assignment 14: Metabolic pathway engineering
- Production of isoprenoid pharmaceuticals by engineered microbes link
- Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli link
Assignment 15: Systems biology
- The evolution of molecular biology into systems biology
- Integrating 'omic information: A bridge between genomics and systems biology
- Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles
Assignment 16: Systems biology and synthetic biology
- Systems biology as a foundation for genome-scale synthetic biology link
- From systems biology to synthetic biology
- Modular approaches to expanding the functions of living matter
Assignment 17: Computational Biology
- Modelling cellular behaviour
- Bioinformatics analysis for genome design and synthetic biology
Assignment 18: Biological networks
- Biological networks
- Programming and engineering biological networks
Assignment 19: Metabolic modeling
- Use of genome-scale microbial models for metabolic engineering
- Global physiological understanding and metabolic engineering of microorganisms based on omics studies
- Microbial regulatory and metabolic networks
Assignment 20: RNA synthetic biology
- RNA synthetic biology
- RNA and RNP as new molecular parts in synthetic biology
Assignment 21: The future of synthetic biology
- Synthetic biology: Navigating the challenges ahead
- Synthetic biology through the prism of scenarios
