CHE.496/2008/Assignments: Difference between revisions
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# '''Global transposon mutagenesis and a minimal mycoplasma genome | # '''Global transposon mutagenesis and a minimal mycoplasma genome | ||
# '''Rebuilding microbial genomes | |||
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====Assignment 10: Dr. George Church's minimal cell work==== | ====Assignment 10: Dr. George Church's minimal cell work==== |
Revision as of 16:26, 8 November 2007
Assigned Readings
Assignment 1: Synthetic biology overview
- Extreme genetic engineering: An introduction to synthetic biology
- Intelligent Life
Assignment 2: Foundational technologies
- Foundations for engineering biology
- A partnership between biology and engineering
Assignment 3: Engineering principles
- Synthetic biology - putting engineering into biology
- Synthetic biology: New engineering rules for an emerging discipline
Assignment 4: Standard biological parts
- Idempotent vector design for standard assembly of biobricks
- Designing biological systems
- Biology by design: Reduction and synthesis of cellular components and behavior
Assignment 5: Bioinformatics and genetic programming
- Systems biology as a foundation for genome-scale synthetic biology
- Another side of genomics: Synthetic biology as a means for the exploitation of whole-genome sequence information
Assignment 6: Practical applications
- Advances in synthetic biology: on the path from prototypes to applications
- Molecular switches for cellular sensors
Assignment 7: Social implications
- The promises and perils of synthetic biology
- Synthetic biology: Navigating the challenges ahead
- Synthetic biology: Caught between property rights, the public domain, & the commons
- Economics of synthetic biology
- DNA synthesis and biological security
- Characterization of the reconstructed 1918 Spanish influenza pandemic virus
Assignment 8: Synthetic genes, biological machines, and minimal genomes
- Genetic parts to program bacteria
- Codon bias and heterologous protein expression
- Fast, cheap and somewhat in control
Assignment 9: Dr. Craig Venter's minimal genome work
- Global transposon mutagenesis and a minimal mycoplasma genome
- Rebuilding microbial genomes
Assignment 10: Dr. George Church's minimal cell work
- Toward synthesis of a minimal cell
Assignment 11: Dr. Michael Elowitz's genetic circuit engineering work
- A synthetic oscillatory network of transcriptional regulators
Assignment 12: Dr. Jim Collins' genetic circuit engineering work
- Construction of a genetic toggle switch in Escherichia coli
- Engineered gene circuits
Assignment 13: Dr. Chris Voigt's genetic circuit engineering work
- Environmentally controlled invasion of cancer cells by engineered bacteria
- Environmental signal integration by a modular AND gate
Assignment 14: Dr. Jay Keasling's metabolic pathway engineering work
- Production of isoprenoid pharmaceuticals by engineered microbes
Assignment 15: Systems biology and the omic sciences
- The evolution of molecular biology into systems biology
- From systems biology to synthetic biology
- Bioinformatics analysis for genome design and synthetic biology
- Integrating 'omic information: A bridge between genomics and systems biology
- Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles
- Use of genome-scale microbial models for metabolic engineering
- Microbial regulatory and metabolic networks
- Global physiological understanding and metabolic engineering of microorganisms based on omics studies
- Biological networks
- Programming and engineering biological networks
- Modular approaches to expanding the functions of living matter
Assignment 16: Computational Biology
- From molecular to modular cell biology
- Modelling cellular behaviour
Assignment 17: Computational biology
Assignment 18: Metabolic flux analysis
Assignment 19: Genome-scale metabolic models
Assignment 20: Modeling genetic regulatory networks
Assignment 21: Systems biotechnology