CHE.496/2008/Responses/a10: Difference between revisions

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*Discussion leader: Kevin Hershey [[CHE.496/2008/Schedule/Genetic circuit engineering| (Discussion guide)]]
*Discussion leader: Kevin Hershey [[CHE.496/2008/Schedule/Genetic circuit engineering| (Discussion guide)]]
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*--Eyad Lababidi's response-*
**A synthetic oscillatory network of transcriptional regulators**
- This article talks about creating an oscillatory network out of bricks that would act like inverters by alternating repressors. it seemed liek a pretty basic idea when you compare it to circuits but what the real goal seemed to be creating these inverters that would be in the network. The article talked about using well known bio bricks that would have the equivalent of being good at turning on and turning off. in chemical terms it talked about when being repressed the protein would not be synthesized and when it is being translated by mrna the protein would be in high production. This project goes back to the fundamentals so that later on a research could choose from a plethora of different proteins that can behave like inverters.

Revision as of 12:55, 25 February 2008

CHE.496: Biological Systems Design Seminar

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Genetic circuit engineering (part 1)


  • --Eyad Lababidi's response-*
    • A synthetic oscillatory network of transcriptional regulators**

- This article talks about creating an oscillatory network out of bricks that would act like inverters by alternating repressors. it seemed liek a pretty basic idea when you compare it to circuits but what the real goal seemed to be creating these inverters that would be in the network. The article talked about using well known bio bricks that would have the equivalent of being good at turning on and turning off. in chemical terms it talked about when being repressed the protein would not be synthesized and when it is being translated by mrna the protein would be in high production. This project goes back to the fundamentals so that later on a research could choose from a plethora of different proteins that can behave like inverters.