CHE.496/2008/Responses/a12: Difference between revisions

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===Eyad Lababidi's Response===
===Eyad Lababidi's Response===
*''Bioengineering novel in vitro metabolic pathways using synthetic biology''
**Okay so i read this article but i constantly had to reread sections because i was missing the point. I believe it was about how to create new enzymes in cells, but i really wasn't sure how it was relevant to us or how the methods they were using were relevant to us, so the article seemed a bit dense to me and to be honest i didnt really get much out of it, sorry George.
*''Synthetic biology for synthetic chemistry''
*''Synthetic biology for synthetic chemistry''
**This articles is a very good all encompassing crash course to how one would start a Igem project. Each important piece of a synthetic bio cell is defined and explained to best be setup for a cell meant to be harnessed for synthetic biology. The insight on factors that could destroy a project especially through differing metabolic rates seems useful. other explanations were also useful such as why synth bio parts have been mutated to be a bare bones chassis that will readily take up plasmid vectors and evolutionary abilities of the cell have been disabled such as to not evolve away from containing the plasmid.
**This articles is a very good all encompassing crash course to how one would start a Igem project. Each important piece of a synthetic bio cell is defined and explained to best be setup for a cell meant to be harnessed for synthetic biology. The insight on factors that could destroy a project especially through differing metabolic rates seems useful. other explanations were also useful such as why synth bio parts have been mutated to be a bare bones chassis that will readily take up plasmid vectors and evolutionary abilities of the cell have been disabled such as to not evolve away from containing the plasmid.
[[User:Eyad Lababidi|Eyad Lababidi]] 01:25, 10 March 2008 (EDT)

Revision as of 22:25, 9 March 2008

CHE.496: Biological Systems Design Seminar

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Metabolic pathway engineering


Eyad Lababidi's Response

  • Bioengineering novel in vitro metabolic pathways using synthetic biology
    • Okay so i read this article but i constantly had to reread sections because i was missing the point. I believe it was about how to create new enzymes in cells, but i really wasn't sure how it was relevant to us or how the methods they were using were relevant to us, so the article seemed a bit dense to me and to be honest i didnt really get much out of it, sorry George.
  • Synthetic biology for synthetic chemistry
    • This articles is a very good all encompassing crash course to how one would start a Igem project. Each important piece of a synthetic bio cell is defined and explained to best be setup for a cell meant to be harnessed for synthetic biology. The insight on factors that could destroy a project especially through differing metabolic rates seems useful. other explanations were also useful such as why synth bio parts have been mutated to be a bare bones chassis that will readily take up plasmid vectors and evolutionary abilities of the cell have been disabled such as to not evolve away from containing the plasmid.

Eyad Lababidi 01:25, 10 March 2008 (EDT)