CHE.496/2008/Responses/a14

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(Biological networks)
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==Biological networks==
==Biological networks==
*Discussion leader: Eyad Lababidi [[CHE.496/2008/Schedule/Biological networks| (Discussion guide)]]
*Discussion leader: Eyad Lababidi [[CHE.496/2008/Schedule/Biological networks| (Discussion guide)]]
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===Kevin Hershey's Response===
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*''Biological Networks''
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**The review by Arkin and Alm discusses the development of systems using gene interactions in biological systems. It discusses how this is possible through high-throughput genetic sequencing techniques. It then goes on to discuss biological networks, and the modules and motifs which compose it. Alm and Arkin define modules as discrete units of function separable from the whole and motifs are the arrangement of specific molecular functions to do something useful. These networks can then be engineered, using synthetic biology practices, but multiple networks tends to complicate things with interference.
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*''Programming and Engineering Biological Networks''
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**This article is very similar to the Chin article for 4/2/2008. In this article, Chin begins by discussing a mammalian toggle switch. Then, he moves onto yet another explanation of Ron Weiss’s ‘bullseye’ configuration. He then finishes by discussing post-translational control and orthogonal ribosomes, as he did in the article Modular Approaches to Expanding the Functions of Living Matter.
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*'''[[User:KPHershey|KPHershey]] 12:26, 2 April 2008 (EDT)'''
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Revision as of 12:26, 2 April 2008

CHE.496: Biological Systems Design Seminar

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Biological networks


Kevin Hershey's Response

  • Biological Networks
    • The review by Arkin and Alm discusses the development of systems using gene interactions in biological systems. It discusses how this is possible through high-throughput genetic sequencing techniques. It then goes on to discuss biological networks, and the modules and motifs which compose it. Alm and Arkin define modules as discrete units of function separable from the whole and motifs are the arrangement of specific molecular functions to do something useful. These networks can then be engineered, using synthetic biology practices, but multiple networks tends to complicate things with interference.
  • Programming and Engineering Biological Networks
    • This article is very similar to the Chin article for 4/2/2008. In this article, Chin begins by discussing a mammalian toggle switch. Then, he moves onto yet another explanation of Ron Weiss’s ‘bullseye’ configuration. He then finishes by discussing post-translational control and orthogonal ribosomes, as he did in the article Modular Approaches to Expanding the Functions of Living Matter.
  • KPHershey 12:26, 2 April 2008 (EDT)

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