CHE.496/2009/Schedule/Oral presentations of part design/Group 1: Difference between revisions

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*Description:
*Description:
**The genetic circuit would function as a standard AND gate with the exception that it does not function on binary input but ternary and possibly quaternary input if we can make it possible. While it is possible to build a circuit that can encode multiple inputs by linking a series of AND gates in a cascade as has been done in electronic circuits and VLSI design. However, in a biological system there are stoichastic effects that can interfere with a large biological network. Another consideration is that for such a network of multiple binary AND gates in a biological organism, the inputs would have to be different from each other because otherwise it would defeat the purpose of the genetic circuits. Having an AND gate with multiple inputs would eliminate the issues listed above and would be far more efficient and faster. The AND gate could be constructed of genes or possibly orthogonal Ribosomes.
**The genetic circuit would function as a standard AND gate with the exception that it does not function on binary input but ternary and possibly quaternary input if we can make it possible. While it is possible to build a circuit that can encode multiple inputs by linking a series of AND gates in a cascade as has been done in electronic circuits and VLSI design. However, in a biological system there are stoichastic effects that can interfere with a large biological network. Another consideration is that for such a network of multiple binary AND gates in a biological organism, the inputs would have to be different from each other because otherwise it would defeat the purpose of the genetic circuits. Having an AND gate with multiple inputs would eliminate the issues listed above and would be far more efficient and faster. The AND gate could be constructed of genes or possibly orthogonal Ribosomes.
**Source & References
*Source & References
Orthogonal Ribosomes:
**Orthogonal Ribosomes:
[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VS6-4KD5BRS-1&_user=709071&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000039638&_version=1&_urlVersion=0&_userid=709071&md5=db5cc43575757192aeb473640e4873b0 Programming and engineering biological networks]
**[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VS6-4KD5BRS-1&_user=709071&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000039638&_version=1&_urlVersion=0&_userid=709071&md5=db5cc43575757192aeb473640e4873b0 Programming and engineering biological networks]
**[http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T36-4RTKK35-1&_user=709071&_coverDate=04%2F09%2F2008&_alid=899360892&_rdoc=1&_fmt=high&_orig=search&_cdi=4938&_st=12&_docanchor=&view=c&_ct=1&_acct=C000039638&_version=1&_urlVersion=0&_userid=709071&md5=2e7e84538434a3465a0c1704b07ae696 Mining logic gates in prokaryotic transcriptional regulation networks]
* Part 2
* Part 2
* Part 3
* Part 3

Revision as of 17:09, 9 April 2009

CHE.496: Biological Systems Design Seminar

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Group 1

  • Members: Patrick Gildea & Thaddeus Webb

Parts

  • Part 1: Multiple input AND gate
  • Description:
    • The genetic circuit would function as a standard AND gate with the exception that it does not function on binary input but ternary and possibly quaternary input if we can make it possible. While it is possible to build a circuit that can encode multiple inputs by linking a series of AND gates in a cascade as has been done in electronic circuits and VLSI design. However, in a biological system there are stoichastic effects that can interfere with a large biological network. Another consideration is that for such a network of multiple binary AND gates in a biological organism, the inputs would have to be different from each other because otherwise it would defeat the purpose of the genetic circuits. Having an AND gate with multiple inputs would eliminate the issues listed above and would be far more efficient and faster. The AND gate could be constructed of genes or possibly orthogonal Ribosomes.
  • Source & References
  • Part 2
  • Part 3
  • Part 4


Part 5

Purpose

text

Description

text

Source & References

  1. source
  2. reference

Part 6

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