Cell Transformation Group:Ongoing Research

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==''p53<sup>-/-</sup> mice''==
==''p53<sup>-/-</sup> mice''==
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We have two strains of p53 defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.
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We have two strains of [http://p53.bii.a-star.edu.sg/index.php p53] defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.

Revision as of 17:35, 15 January 2009

A549_web.jpg



YBX-1

Our primary research focus is the investigation of YBX-1 structure, function and interactions in vitro and ex vivo as a cancer oncogene.

Telomeres

Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically Glioblastoma multiforme.

p53-/- mice

We have two strains of p53 defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.

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