Cell Transformation Group:Ongoing Research

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{{Cell Transformation Group}}
{{Cell Transformation Group}}
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==''YBX-1''==
==''YBX-1''==
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Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically [http://en.wikipedia.org/wiki/Glioblastoma_multiforme Glioblastoma multiforme].
Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically [http://en.wikipedia.org/wiki/Glioblastoma_multiforme Glioblastoma multiforme].
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==''p53 mutant mice''==
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We have two strains of [http://p53.bii.a-star.edu.sg/index.php p53] defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.

Current revision

A549_web.jpg



YBX-1

Our primary research focus is the investigation of YBX-1 structure, function and interactions in vitro and ex vivo as a cancer oncogene.

Telomeres

Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically Glioblastoma multiforme.

p53 mutant mice

We have two strains of p53 defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.

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