Cell Transformation Group:Ongoing Research: Difference between revisions
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==''p53<sup>-/-</sup> mice''== | ==''p53<sup>-/-</sup> mice''== | ||
We have two strains of p53 defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis. | We have two strains of [http://p53.bii.a-star.edu.sg/index.php p53] defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis. | ||
Revision as of 14:35, 15 January 2009
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YBX-1
Our primary research focus is the investigation of YBX-1 structure, function and interactions in vitro and ex vivo as a cancer oncogene.
Telomeres
Another part of our lab investigates the function of telomere length and telomere maintenance mechanisms in the growth and proliferation of brain cancers, specifically Glioblastoma multiforme.
p53-/- mice
We have two strains of p53 defective mutant mice which are currently being investigated for the role of the particular mutations in oncogenesis.
