Cellular and molecular bioengineering laboratory

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[[Image:CellCover4.jpg|thumb|300px|right|Bardet-Biedl Syndrome (BBS): a disease of the cilium.<br> BBS patients suffer from retinal degeneration (upper left), kidney malformations (lower right), obesity and polydactyly (upper right). Recently, we discovered that a core complex of BBS proteins (the BBSome) coordinates vesicular transport to the primary cilium (lower left).]]
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The Nachury Lab is part of the department of [http://mcp.stanford.edu/ Molecular and Cellular Physiology] at [http://med.stanford.edu/ Stanford University School of Medicine].<br>Our lab is interested in using a combination of interdisciplinary approaches encompassing protein biochemistry, cell biology, in vitro assays, digital microscopy and mammalian cell engineering to study the molecular etiology of complex hereditary human diseases.<br>
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A major focus of the lab is the study of the primary cilium, a once-obscure cellular organelle that has recently been "re-discovered" for its role in a number of signaling pathways (Hedgehog, Planar Cell Polarity, PDGF,..). Most fascinatingly, molecular defects in cilium biogenesis lead to a variety of hereditary disorders (so-called "ciliopathies") characterized by retinal degeneration, kidney cysts, brain malformations, obesity, polydactyly, randomization of left-right asymmetry, etc. Our major goal is to characterize these ciliopathies at the molecular and cellular levels to gain insight into the basic mechanisms of primary cilium biogenesis and to discover novel ciliary signaling pathways.
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<h3>People</h3>
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• [[User:Junghae Suh| Principal Investigator]]<br>
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• [[User:amack| Lab Manager]]<br>
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[[Suh:undergradutes| Undergraduate Students]]<br>
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• [[Suh:lab mascots| Lab Mascots (technically not people)]]<br>
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<h3>Research</h3>
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• [[Suh:Research|Research Overview]]<br>
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• [[Suh:Projects|Projects]]<br>
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• [[Suh:Publications|Publications]]<br>
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• [[Suh:Links|Links]]<br>
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<h3>Resources</h3>
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• [[Suh:Protocols|Protocols]]<br>
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• [[Suh:Equipment|Equipment]]<br>
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• [[Suh:Materials|Materials]]<br>
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• [[Suh:Back Door|Internal]]<br>
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<h3>Contact Us</h3>
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Junghae Suh, Ph.D.
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Assistant Professor <br>
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Dept of Bioengineering <br>
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Rice University <br>
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116C Keck Hall <br>
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Houston, TX <br>
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jsuh@rice.edu <br>
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Revision as of 02:55, 17 July 2008

Research

Research Overview
Projects
Publications
Links

Resources

Protocols
Equipment
Materials
Internal

Contact Us

Junghae Suh, Ph.D. Assistant Professor
Dept of Bioengineering
Rice University
116C Keck Hall
Houston, TX
jsuh@rice.edu

Suh Home
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