Chalmers

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Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling. <br/>
Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling. <br/>
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The main focuses of the lab are on: <br/>
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Our [[Chalmers:Research| current projects]] are: <br/>
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- [[Chalmers:Research|Determination of the mariner transposition mechanism]] <br/>
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- To determine the mechanism of mariner transposition <br/>
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- [[Chalmers:Research|Molecular domestication of mariner transposons in the human genome]] <br/>
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- To find the functions of a primate-specific domesticated transposases <br/>
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- [[Chalmers:Research|Development of mariner transposons as gene vectors]] <br/>
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- To engineer mariner transposons and their derivatives as gene vectors <br/>
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'''Last paper:'''
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'''
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Claeys Bouuaert C, Chalmers R. Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target. PLoS ONE. 2013 Jan 14;8(1): e53690.
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== Last paper: ==
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'''
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Claeys Bouuaert C, Lipkow K, Andrews SS, Liu D, Chalmers R. [http://elife.elifesciences.org/content/2/e00668 The autoregulation of a eukaryotic DNA transposon.] Elife. 2013 Jun 18;2:e00668.

Current revision

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Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling.

Our current projects are:
- To determine the mechanism of mariner transposition
- To find the functions of a primate-specific domesticated transposases
- To engineer mariner transposons and their derivatives as gene vectors


Last paper:

Claeys Bouuaert C, Lipkow K, Andrews SS, Liu D, Chalmers R. The autoregulation of a eukaryotic DNA transposon. Elife. 2013 Jun 18;2:e00668.

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