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Revision as of 21:10, 26 November 2007
Simon Chan Lab
Welcome to the Chan Lab at UC Davis. We study chromosome inheritance and centromere function using the small flowering plant Arabidopsis thaliana. |
Lab Members• Dr. Simon Chan Former Lab Members
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Researchmore to come soon |
Resources• Protocols |
Contact UsLife Sciences Building LS1215 (lab) |
Publications
Two-step recruitment of RNA-directed DNA methylation to tandem repeats. Increased outcrossing in hothead mutants. Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis. An ARGONAUTE4-containing nuclear processing center co-localized with Cajal bodies in Arabidopsis thaliana. RNAi, DRD1 and Histone Methylation Actively Target Developmentally Important Non-CG DNA Methylation in Arabidopsis. Gardening the genome: DNA methylation in Arabidopsis thaliana. Applications of DNA tiling arrays for whole-genome analysis. siRNA-induced transcriptional gene silencing in human cells. RNA silencing genes control de novo DNA methylation.
Telomeres and telomerase. Telomerase and ATM/Tel1p protect telomeres from non-homologous end-joining. New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin. Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Molecular manifestations and molecular determinants of telomere capping. |