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'''Chan Lab'''<br>
'''Simon Chan Lab'''
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'''''"finest haploids since 2009"'''''<br>
[http://www-plb.ucdavis.edu/ Department of Plant Biology], [http://www.ucdavis.edu/ UC Davis] and [http://www.hhmi.org HHMI]
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[[Image:arabidopsis.jpg|left|thumb||200 px|<i>Arabidopsis thaliana</i>]]
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[[Chan|Home]]
<font face="Helvetica"><b>Welcome to the Chan Lab at UC Davis.</b>
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[[Chan:Research|Research]]
We study chromosome inheritance and genome stability using the small flowering plant <i>[http://www.arabidopsis.org/portals/education/aboutarabidopsis.jsp Arabidopsis thaliana]</i>.
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[[Chan:Publications|Publications]]
 
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[[Chan:People|People]]
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[[Chan:Links|Links]]
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[[Chan:Bioinformatics Sites|Bioinformatics]]
 
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<h3>Lab Members</h3>
[[Chan:Contact|Contact]]
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&bull; [[User:Simon Chan|Dr. Simon Chan]]<BR>
&bull; [[User:Joseph Ramahi|Joseph Ramahi]]<BR>
&bull; [[User:Pak Kwong|Pak Kwong]]<BR>
&bull; [[User:Christian Santa Maria|Christian Santa Maria]]<BR>
&bull; [[User:Ron Menorca|Ron Menorca]]<BR>
 
<h3>Former Lab Members</h3>
&bull; [[User:Jodi Stewart|Jodi Stewart]]<BR>
 
 
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<h3>Research</h3>
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more to come soon
'''Welcome to Simon Chan's Lab'''
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'''With deep regret we inform you that Simon Chan (1974-2012) has passed away on Aug 22nd at an age of 38 '''<br>
<h3>Resources</h3>
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&bull; [[Chan:Protocols|Protocols]]<br>
&bull; [[Chan:Teaching|Teaching]]<br>
&bull; [[Chan:Links|Links]]<br>
&bull; [[Chan:Bioinformatics Sites|Bioinformatics Sites]]<br>
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<h3>Contact Us</h3>
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Additional information can be found on the [http://bmcdb.wordpress.com BMCDB blog] and the [http://www.plb.ucdavis.edu/labs/srchan/ Department of Plant Biology website].<br>
Life Sciences Building LS1215 (lab)<br>
<br>
Life Sciences Building LS1220 (office)<br>
<br>'''For any comments, notes, or requests, please contact Ravi at ravigenome@gmail.com Mohan at mpamarimuthu@ucdavis.edu or Han at suprduprhan@gmail.com or Daniël at dpmelters@me.com'''<br>
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<b>Lab Phone:</b> (530) 754 9789<br>
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<b>Office Phone:</b> (530) 754 9652<br>
We study chromosome inheritance using the small plant <i>[http://www.arabidopsis.org/portals/education/aboutarabidopsis.jsp Arabidopsis thaliana]</i>.
<b>e-mail:</b> srchan [ at ] ucdavis.edu<br>
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[[Image:haploids.jpg|thumb|none|365 px|Haploid plants (represented by pink pots) have only one copy of each chromosome, and are very useful in plant breeding. We have produced haploids by manipulating centromeres. Image by [http://www.onemicron.com/ Janet Iwasa].]]
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<br>'''For any comments, notes, or requests, please contact Ravi at ravigenome@gmail.com or Han at suprduprhan@gmail.com or Daniël at dpmelters@me.com'''<br>
 
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<h3><b>Publications</b></h3>
 
 
Please contact Simon if you would like the pdf file.
 
 
<b>Postdoc research on DNA methylation and gene silencing:</b>
 
Two-step recruitment of RNA-directed DNA methylation to tandem repeats.
Chan, S.W.L., Zhang, X.Y., Bernatavichute, Y.V. and Jacobsen, S.E.
PLoS Biology 4 No. 11 e363 (2006)
 
Increased outcrossing in hothead mutants.
Peng P., Chan, S.W.L., Shah, G.A. and Jacobsen, S.E.
Nature 443, E8 (2006)
 
Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis.
Zhang, X.*, Yazaki, J.*, Sundaresan, A.*, Cokus, S.*, Chan, S.W.L., Chen, H., Henderson, I.R., Shinn, P., Pellegrini, M., Jacobsen, S.E., and Ecker, J.R.
Cell 126, 1189-1201 (2006)
 
An ARGONAUTE4-containing nuclear processing center co-localized with Cajal bodies in Arabidopsis thaliana.
Li, C.F., Pontes, O., El-Shami, M., Henderson, I.R., Bernatavichute, Y.V., Chan, S.W.L., Lagrange, T., Pikaard, C.S. and Jacobsen, S.E.
Cell 126, 93-106 (2006)
 
Chan, S.W.L., Henderson, I.R., Zhang, X.Y., Chien, J.S.C., Shah, G. and Jacobsen, S.E.
RNAi, DRD1 and Histone Methylation Actively Target Developmentally Important Non-CG DNA Methylation in Arabidopsis.
PLoS Genetics 2, No. 6 e83 (2006)
 
Chan, S.W.L.*, Henderson, I.R.* and Jacobsen, S.E.
Gardening the genome: DNA methylation in Arabidopsis thaliana.
Nature Reviews Genetics 6, 351-360 (2005) [review article]
 
Mockler, T.C., Chan, S., Sundaresan A., Chen, H., Jacobsen S.E. and Ecker, J.R.
Applications of DNA tiling arrays for whole-genome analysis.
Genomics 85, 1-15 (2005) [review article]
 
Morris, K.V., Chan, S.W.L., Jacobsen, S.E. and Looney, D.J.
siRNA-induced transcriptional gene silencing in human cells.
Science 305, 1289-1292 (2004)
 
Chan, S.W.L., Zilberman D., Xie, Z., Johansen, L.K., Carrington, J.C. and Jacobsen, S.E.
RNA silencing genes control de novo DNA methylation.
Science 303, 1336 (2004)
 
 
<b>PhD research on telomeres and telomerase:</b>
 
Chan, S.R.W.L. and Blackburn, E.H.
Telomeres and telomerase.
Phil. Trans. R. Soc. Lond. B 359, 109-121 (2004)
 
Chan, S.W.L. and Blackburn, E.H.
Telomerase and ATM/Tel1p protect telomeres from non-homologous end-joining.
Molecular Cell 11, 1379-1387 (2003)
 
Chan, S.W.L. and Blackburn, E.H.
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin.
Oncogene 21, 553-563 (2002) [review article]
 
Chan, S.W.L., Chang, J., Prescott, J. and Blackburn, E.H.
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases.
Current Biology 11, 1240-1250 (2001)
 
Blackburn, E.H., Chan, S., Chang, J., Fulton, T.B., Krauskopf, A., McEachern, M., Prescott, J., Roy, J., Smith, C. and Wang, H.
Molecular manifestations and molecular determinants of telomere capping.
Cold Spring Harbor Symposia on Quantitative Biology, 65, 253-263 (2000)
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Revision as of 21:16, 19 December 2012


Chan Lab
"finest haploids since 2009"
Department of Plant Biology, UC Davis and HHMI

Welcome to Simon Chan's Lab

With deep regret we inform you that Simon Chan (1974-2012) has passed away on Aug 22nd at an age of 38


Additional information can be found on the BMCDB blog and the Department of Plant Biology website.


For any comments, notes, or requests, please contact Ravi at ravigenome@gmail.com Mohan at mpamarimuthu@ucdavis.edu or Han at suprduprhan@gmail.com or Daniël at dpmelters@me.com


We study chromosome inheritance using the small plant Arabidopsis thaliana.

Haploid plants (represented by pink pots) have only one copy of each chromosome, and are very useful in plant breeding. We have produced haploids by manipulating centromeres. Image by Janet Iwasa.


For any comments, notes, or requests, please contact Ravi at ravigenome@gmail.com or Han at suprduprhan@gmail.com or Daniël at dpmelters@me.com

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