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'''Chan Lab'''<br>
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'''Simon Chan Lab'''<br>
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[http://www-plb.ucdavis.edu/index.html Section of Plant Biology] at [http://www.ucdavis.edu/ UC Davis]
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'''''"finest haploids since 2009"'''''<br>
[http://www-plb.ucdavis.edu/ Department of Plant Biology], [http://www.ucdavis.edu/ UC Davis] and [http://www.hhmi.org HHMI]
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[[Image:arabidopsis.jpg|left|thumb||200 px|<i>Arabidopsis thaliana</i>]]
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<font face="Helvetica"><b>Welcome to the Chan Lab at UC Davis.</b>
 
We study chromosome inheritance and centromere function using the small flowering plant <i>[http://www.arabidopsis.org/portals/education/aboutarabidopsis.jsp Arabidopsis thaliana]</i>.
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[[Chan|Home]]
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[[Chan:Research|Research]]
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[[Chan:Publications|Publications]]
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[[Chan:People|People]]
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[[Chan:Links|Links]]
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[[Chan:Bioinformatics Sites|Bioinformatics]]
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[[Chan:Contact|Contact]]
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<h3>Lab Members</h3>
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&bull; [[User:Simon Chan|Dr. Simon Chan]]<BR>
'''Welcome to Simon Chan's Lab'''
&bull; [[User:Joseph Ramahi|Joseph Ramahi]]<BR>
<br>
&bull; [[User:Pak Kwong|Pak Kwong]]<BR>
<br>
&bull; [[User:Christian Santa Maria|Christian Santa Maria]]<BR>
'''With deep regret we inform you that Simon Chan (1974-2012) has passed away on Aug 22nd at an age of 38 '''<br>
&bull; [[User:Ron Menorca|Ron Menorca]]<BR>
&bull; Jessica Wald, rotation student<br>
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<br>
[[Information about joining our lab]]


<h3>Former Lab Members</h3>
&bull; [[User:Jodi Stewart|Jodi Stewart]]<BR>
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<h3>Research</h3>
more to come soon
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<h3>Resources</h3>
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&bull; [[Chan:Protocols|Protocols]]<br>
&bull; [[Chan:Teaching|Teaching]]<br>
&bull; [[Chan:Links|Links]]<br>
&bull; [[Chan:Resources|UC Davis Facilities and Resources]]<br>
&bull; [[Chan:Bioinformatics Sites|Bioinformatics Sites]]<br>
&bull; [http://comailab.genomecenter.ucdavis.edu/index.php/Lab_Meeting Lab Meeting Schedule]<br></div>
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<h3>Contact Us</h3>
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Life Sciences Building LS1215 (lab)<br>
Life Sciences Building LS1220 (office)<br>
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<b>Lab Phone:</b> (530) 754 9789<br>
<b>Office Phone:</b> (530) 754 9652<br>
<b>e-mail:</b> srchan [ at ] ucdavis.edu<br>
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<h3><b>Publications</b></h3>
Please contact Simon if you would like the pdf file.<br>
<br>
<br>
<b>Postdoc research on DNA methylation and gene silencing:</b>
Additional information can be found on the [http://bmcdb.wordpress.com BMCDB blog] and the [http://www.plb.ucdavis.edu/labs/srchan/ Department of Plant Biology website].<br>
 
Two-step recruitment of RNA-directed DNA methylation to tandem repeats.<br>
Chan, S.W.L., Zhang, X.Y., Bernatavichute, Y.V. and Jacobsen, S.E.<br>
PLoS Biology 4 No. 11 e363 (2006)
 
Increased outcrossing in ''hothead'' mutants.<br>
Peng P., Chan, S.W.L., Shah, G.A. and Jacobsen, S.E.<br>
Nature 443, E8 (2006)
 
Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in ''Arabidopsis''.<br>
Zhang, X.*, Yazaki, J.*, Sundaresan, A.*, Cokus, S.*, Chan, S.W.L., Chen, H., Henderson, I.R., Shinn, P., Pellegrini, M., Jacobsen, S.E., and Ecker, J.R.<br>
Cell 126, 1189-1201 (2006)
 
An ARGONAUTE4-containing nuclear processing center co-localized with Cajal bodies in ''Arabidopsis thaliana''.<br>
Li, C.F., Pontes, O., El-Shami, M., Henderson, I.R., Bernatavichute, Y.V., Chan, S.W.L., Lagrange, T., Pikaard, C.S. and Jacobsen, S.E.<br>
Cell 126, 93-106 (2006)
 
RNAi, DRD1 and Histone Methylation Actively Target Developmentally Important Non-CG DNA Methylation in ''Arabidopsis''.<br>
Chan, S.W.L., Henderson, I.R., Zhang, X.Y., Chien, J.S.C., Shah, G. and Jacobsen, S.E.<br>
PLoS Genetics 2, No. 6 e83 (2006)
 
Gardening the genome: DNA methylation in ''Arabidopsis thaliana''.<br>
Chan, S.W.L.*, Henderson, I.R.* and Jacobsen, S.E.<br>
Nature Reviews Genetics 6, 351-360 (2005) [review article]
 
Applications of DNA tiling arrays for whole-genome analysis.<br>
Mockler, T.C., Chan, S., Sundaresan A., Chen, H., Jacobsen S.E. and Ecker, J.R.<br>
Genomics 85, 1-15 (2005) [review article]
 
siRNA-induced transcriptional gene silencing in human cells.<br>
Morris, K.V., Chan, S.W.L., Jacobsen, S.E. and Looney, D.J.<br>
Science 305, 1289-1292 (2004)
 
RNA silencing genes control de novo DNA methylation.<br>
Chan, S.W.L., Zilberman D., Xie, Z., Johansen, L.K., Carrington, J.C. and Jacobsen, S.E.<br>
Science 303, 1336 (2004)
 
 
<b>PhD research on telomeres and telomerase:</b>
 
Telomeres and telomerase.<br>
Chan, S.R.W.L. and Blackburn, E.H.<br>
Phil. Trans. R. Soc. Lond. B 359, 109-121 (2004)
 
Telomerase and ATM/Tel1p protect telomeres from non-homologous end-joining.<br>
Chan, S.W.L. and Blackburn, E.H.<br>
Molecular Cell 11, 1379-1387 (2003)
 
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin.<br>
Chan, S.W.L. and Blackburn, E.H.<br>
Oncogene 21, 553-563 (2002) [review article]
 
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases.<br>
Chan, S.W.L., Chang, J., Prescott, J. and Blackburn, E.H.<br>
Current Biology 11, 1240-1250 (2001)
 
Molecular manifestations and molecular determinants of telomere capping.<br>
Blackburn, E.H., Chan, S., Chang, J., Fulton, T.B., Krauskopf, A., McEachern, M., Prescott, J., Roy, J., Smith, C. and Wang, H.<br>
Cold Spring Harbor Symposia on Quantitative Biology, 65, 253-263 (2000)<br>
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note: * denotes equal contribution<br>
<br>'''For any comments, notes, or requests, please contact Ravi at ravigenome@gmail.com Mohan at mpamarimuthu@ucdavis.edu or Han at suprduprhan@gmail.com'''<br>
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We study chromosome inheritance using the small plant <i>[http://www.arabidopsis.org/portals/education/aboutarabidopsis.jsp Arabidopsis thaliana]</i>.
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[[Image:haploids.jpg|thumb|none|365 px|Haploid plants (represented by pink pots) have only one copy of each chromosome, and are very useful in plant breeding. We have produced haploids by manipulating centromeres. Image by [http://www.onemicron.com/ Janet Iwasa].]]
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Latest revision as of 02:26, 11 November 2014


Chan Lab
"finest haploids since 2009"
Department of Plant Biology, UC Davis and HHMI

Welcome to Simon Chan's Lab

With deep regret we inform you that Simon Chan (1974-2012) has passed away on Aug 22nd at an age of 38


Additional information can be found on the BMCDB blog and the Department of Plant Biology website.


For any comments, notes, or requests, please contact Ravi at ravigenome@gmail.com Mohan at mpamarimuthu@ucdavis.edu or Han at suprduprhan@gmail.com


We study chromosome inheritance using the small plant Arabidopsis thaliana.

Haploid plants (represented by pink pots) have only one copy of each chromosome, and are very useful in plant breeding. We have produced haploids by manipulating centromeres. Image by Janet Iwasa.


'

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