Chan:Daniel P Melters: Difference between revisions

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Daniël received his BSc and MSc from [http://www.leiden.edu/ Leiden University] in [http://en.wikipedia.org/wiki/Netherlands the Netherlands]. For his MSc he worked in [http://www.niams.nih.gov/Research/Ongoing_Research/Branch_Lab/Autoimmunity/rag.asp Dr. Lipsky's lab] at the [http://www.nih.gov/ NIH], studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in [http://leidsewetenschappers.leidenuniv.nl/show_en.php3?medewerker_id=662 Prof. Dr. de Kloet's lab] at the [http://www.lacdr.nl/ LACDR] / [http://www.leiden.edu/ Leiden University] identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined [http://nephrology.medicine.ucsf.edu/people/david_pearce.html Dr. Pearce's lab] at [http://www.ucsf.edu/ UCSF], working on understanding the signaling cascade regulation sodium reabsorption in kidney epithelium cells upon aldosterone treatment. His work has led to three publications:
Daniël received his BSc and MSc from [http://www.leiden.edu/ Leiden University] in [http://en.wikipedia.org/wiki/Netherlands the Netherlands]. For his MSc he worked in [http://www.niams.nih.gov/Research/Ongoing_Research/Branch_Lab/Autoimmunity/rag.asp Dr. Lipsky's lab] at the [http://www.nih.gov/ NIH], studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in [http://leidsewetenschappers.leidenuniv.nl/show_en.php3?medewerker_id=662 Prof. Dr. de Kloet's lab] at the [http://www.lacdr.nl/ LACDR] / [http://www.leiden.edu/ Leiden University] identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined [http://nephrology.medicine.ucsf.edu/people/david_pearce.html Dr. Pearce's lab] at [http://www.ucsf.edu/ UCSF], working on understanding the signaling cascade regulation sodium reabsorption in kidney epithelium cells upon aldosterone treatment. His work has led to three publications:
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- '''Melters DP''', Paliulis LV, Korf IF, Chan SW. Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis. ''Chromosome Res.'' '''2012''' Jul 6. [Epub ahead of print] [http://www.springerlink.com/content/p25765h8x9687227/ link]
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Revision as of 11:01, 25 July 2012


Chan Lab
Department of Plant Biology at UC Davis



Daniël is a fourth year PhD student from the Biochemical, Molecular, Cellular and Developmental Biology (BMCDB) Graduate Group and he is a shared student with Ian Korf. Daniël is also a member of the Designated Emphasis in Biotechnology, and was a recipient of the NIH training grant in Biomolecular Technology.

Daniël joined the lab in Spring of 2009, and his research project is focused on the evolution of the centromere tandem repeat sequences in over 300 eurkaryotes using bioinformatics.

Daniël received his BSc and MSc from Leiden University in the Netherlands. For his MSc he worked in Dr. Lipsky's lab at the NIH, studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in Prof. Dr. de Kloet's lab at the LACDR / Leiden University identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined Dr. Pearce's lab at UCSF, working on understanding the signaling cascade regulation sodium reabsorption in kidney epithelium cells upon aldosterone treatment. His work has led to three publications:

- Melters DP, Paliulis LV, Korf IF, Chan SW. Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis. Chromosome Res. 2012 Jul 6. [Epub ahead of print] link

- Soundararajan R, Wang J, Melters DP, Pearce D. Glucocorticoid-induced leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization. J. Biol. Chem. 2010 Dec 17;285(51):39905-13. link
- Soundararajan R, Melters DP, Shih IC, Wang J, Pearce D. Epithelial sodium channel regulated by differential composition of a signaling complex. Proc. Natl. Acad. Sci. U.S.A. 2009 106(19):7804-7809. link
- Soundararajan R, Wang J, Melters DP, Pearce D. Differential activities of glucocorticoid-induced leucine zipper protein isoforms. J. Biol. Chem. 2007 Dec 14;282(50):36303-13. link

click to email Daniël: dpmelters@ucdavis.edu

Follow Daniël on Twitter @DPMelters

Daniël's LinkedIn profile

Daniël's Chasing The Red Queen blog

Daniël also founded and moderates the BMCDB graduate group blog BMCDB blog

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