Chan:Daniel P Melters: Difference between revisions

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Daniël is a fifth year PhD student from the [http://biosci3.ucdavis.edu/GradGroups/BMCDB/ Biochemical, Molecular, Cellular and Developmental Biology (BMCDB) Graduate Group] and he is a shared student with [http://korflab.ucdavis.edu/ Ian Korf]. Daniël is also a member of the [http://www.deb.ucdavis.edu/ Designated Emphasis in Biotechnology], and was a recipient of the NIH training grant in Biomolecular Technology.
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Daniël is a second year PhD student from the [http://biosci2.ucdavis.edu/ggc/cdb/ Cell and Developmental Biology Graduate Group] and he is a shared student with [http://korflab.ucdavis.edu/ Ian Korf]. Daniël is also a member of the [http://www.deb.ucdavis.edu/ Designated Emphasis in Biotechnology], and is currently on his first year with the DEB's NIH training grant in Biomolecular Technology.
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Daniël joined the lab in Spring of 2009, and his research project is focused on the evolution of the centromere tandem repeat sequences in over 300 eurkaryotes using bioinformatics.
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Daniël joined the lab in Spring of 2009, and his research project is focused on the evolution of the centromere repeat sequences in eurkaryotes using bioinformatics.
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Daniël received his BSc and MSc from [http://www.leiden.edu/ Leiden University] in [http://en.wikipedia.org/wiki/Netherlands the Netherlands]. For his MSc he worked in [http://www.niams.nih.gov/Research/Ongoing_Research/Branch_Lab/Autoimmunity/rag.asp Dr. Lipsky's lab] at the [http://www.nih.gov/ NIH], studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in [http://leidsewetenschappers.leidenuniv.nl/show_en.php3?medewerker_id=662 Prof. Dr. de Kloet's lab] at the [http://www.lacdr.nl/ LACDR] / [http://www.leiden.edu/ Leiden University] identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined [http://nephrology.medicine.ucsf.edu/people/david_pearce.html Dr. Pearce's lab] at [http://www.ucsf.edu/ UCSF], working on understanding the signaling cascade regulation sodium reabsorption in kidney epithelium cells upon aldosterone treatment. His work has led to three publications:
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Daniël received his BSc and MSc from [http://www.leiden.edu/ Leiden University] in [http://en.wikipedia.org/wiki/Netherlands the Netherlands]. For his MSc he worked in [http://www.niams.nih.gov/Research/Ongoing_Research/Branch_Lab/Autoimmunity/rag.asp Dr. Lipsky's lab] at the [http://www.nih.gov/ NIH], studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in [http://leidsewetenschappers.leidenuniv.nl/show_en.php3?medewerker_id=662 Prof. Dr. de Kloet's lab] at the [http://www.lacdr.nl/ LACDR] / [http://www.leiden.edu/ Leiden University] identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined [http://nephrology.medicine.ucsf.edu/people/david_pearce.html Dr. Pearce's lab] at [http://www.ucsf.edu/ UCSF], working on understanding the signaling cascade regulation sodium reabsorption in kidney epithelium cells upon aldosterone treatment. His work has led to two publications:
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- Soundararajan R, Melters DP, Shih IC, Wang J, Pearce D. Epithelial sodium channel regulated by differential composition of a signaling complex. ''Proc. Natl. Acad. Sci. U.S.A.'' '''2009''' 106(19):7804-7809. [http://www.pnas.org/content/106/19/7804.long link]
- '''Melters DP''', Paliulis LV, Korf IF, Chan SW. '''2012''' Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis. ''Chromosome Res.'' [Epub ahead of print] [http://www.springerlink.com/content/p25765h8x9687227/ link]
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- Soundararajan R, Wang J, Melters DP, Pearce D. Differential activities of glucocorticoid-induced leucine zipper protein isoforms. ''J. Biol. Chem.'' '''2007''' Dec 14;282(50):36303-13. [http://www.jbc.org/cgi/content/full/282/50/36303?view=long&pmid=17956870 link]
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- Soundararajan R, Wang J, '''Melters DP''', Pearce D. '''2010''' Glucocorticoid-induced leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization. ''J. Biol. Chem.'' 285(51):39905-13. [http://www.jbc.org/content/early/2010/10/14/jbc.M110.161133.abstract?sid=5a1d57fc-050f-46b8-bc38-3389d20e111a link]
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- Soundararajan R, '''Melters DP''', Shih IC, Wang J, Pearce D. '''2009''' Epithelial sodium channel regulated by differential composition of a signaling complex. ''Proc. Natl. Acad. Sci. U.S.A.'' 106(19):7804-7809. [http://www.pnas.org/content/106/19/7804.long link]
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- Soundararajan R, Wang J, '''Melters DP''', Pearce D. '''2007''' Differential activities of glucocorticoid-induced leucine zipper protein isoforms. ''J. Biol. Chem.'' 282(50):36303-13. [http://www.jbc.org/cgi/content/full/282/50/36303?view=long&pmid=17956870 link]
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[mailto:dpmelters@ucdavis.edu click to email Daniël]: dpmelters@ucdavis.edu<br>
[mailto:dpmelters@ucdavis.edu click to '''email''' Daniël]: dpmelters@ucdavis.edu<br>
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Follow Daniël on '''Twitter''' [http://twitter.com/DPMelters/ @DPMelters]<br>
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Daniël's '''LinkedIn''' [http://www.linkedin.com/in/dpmelters/ profile]<br>
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Daniël's '''Chasing The Red Queen''' [http://chasingtheredqueen.blogspot.com/ blog]<br>
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Daniël also founded and moderates the '''BMCDB graduate group blog''' [http://bmcdb.wordpress.com/ BMCDB blog]<br>
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Latest revision as of 01:24, 26 August 2012


Chan Lab

Department of Plant Biology at UC Davis





Daniël is a fifth year PhD student from the Biochemical, Molecular, Cellular and Developmental Biology (BMCDB) Graduate Group and he is a shared student with Ian Korf. Daniël is also a member of the Designated Emphasis in Biotechnology, and was a recipient of the NIH training grant in Biomolecular Technology.

Daniël joined the lab in Spring of 2009, and his research project is focused on the evolution of the centromere tandem repeat sequences in over 300 eurkaryotes using bioinformatics.

Daniël received his BSc and MSc from Leiden University in the Netherlands. For his MSc he worked in Dr. Lipsky's lab at the NIH, studying the B lymphocyte immunoglobulin heavy chain repertoire. For his MSc thesis, Daniël worked in Prof. Dr. de Kloet's lab at the LACDR / Leiden University identifying SNPs in the mineralocorticoid receptor promoter of different inbred mouse strains. Following his MSc he moved to San Francisco where Daniël joined Dr. Pearce's lab at UCSF, working on understanding the signaling cascade regulation sodium reabsorption in kidney epithelium cells upon aldosterone treatment. His work has led to three publications:

- Melters DP, Paliulis LV, Korf IF, Chan SW. 2012 Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis. Chromosome Res. [Epub ahead of print] link

- Soundararajan R, Wang J, Melters DP, Pearce D. 2010 Glucocorticoid-induced leucine zipper 1 stimulates the epithelial sodium channel by regulating serum- and glucocorticoid-induced kinase 1 stability and subcellular localization. J. Biol. Chem. 285(51):39905-13. link
- Soundararajan R, Melters DP, Shih IC, Wang J, Pearce D. 2009 Epithelial sodium channel regulated by differential composition of a signaling complex. Proc. Natl. Acad. Sci. U.S.A. 106(19):7804-7809. link
- Soundararajan R, Wang J, Melters DP, Pearce D. 2007 Differential activities of glucocorticoid-induced leucine zipper protein isoforms. J. Biol. Chem. 282(50):36303-13. link

click to email Daniël: dpmelters@ucdavis.edu

Follow Daniël on Twitter @DPMelters

Daniël's LinkedIn profile

Daniël's Chasing The Red Queen blog

Daniël also founded and moderates the BMCDB graduate group blog BMCDB blog