Chenlab: Difference between revisions
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September, 2016 | September, 2016 | ||
* Kaifu is invited to write a review article to highlight recent progresses in research on broad H3K4me3 | * Kaifu is invited to write a review article to highlight recent progresses in research on broad H3K4me3. | ||
* Dr. Qingshu Meng will be visiting us for 1 year. Dr. Meng has outstanding background in Genomics research, and is a group leader at Beijing Institute of Genomics. Welcome! | * Dr. Qingshu Meng will be visiting us for 1 year. Dr. Meng has outstanding background in Genomics research, and is a group leader at Beijing Institute of Genomics. Welcome! | ||
Revision as of 19:58, 21 September 2016
Chen Laboratory
We are computational epigenetic laboratory interested in the following area:
- Developing new technology to make discovery in high throughput DNA sequencing data. Combining bioinformatics innovations with new sequencing technologies to unravel hidden mystery in biology. Developing statistical solutions for integrative analysis of multiple types of sequencing data, innovativing methodologies to make novel observation or answer new biological questions.
- Understanding gene regulation network that determines cell identity and tissue specificity in development. The identity of a cell is determined by its unique gene expression program. Many factors can regulate or influence transcription, e.g., genomic elements, transcription factors, histone modifications, DNA methylations, and noncoding RNA. Our goal is to investigate not only how each factor works, but also how different factors interact to form a gene regulation network.
- Discovering driver genes of cancer, genetic disease, or other important phenotypes. With Over 10 years research experiences in epigenomics, genomics, and bioinformatics, we are highly interested in developing machine learning algorithms to combine epigenetic and genetic data for disease gene discovery, and to reveal the functional mechanism underlying each discovery using molecular, cellular, and animal models.
Recent news:
September, 2016
- Kaifu is invited to write a review article to highlight recent progresses in research on broad H3K4me3.
- Dr. Qingshu Meng will be visiting us for 1 year. Dr. Meng has outstanding background in Genomics research, and is a group leader at Beijing Institute of Genomics. Welcome!
August, 2016
- Kaifu will be an adjunt assistant professor of Texas A&M.
- Dr. Bo Xia from Georgia Tech will join us as a fresh postdoc soon. Dr. Xia is a PhD of biology and Master of computer science. Welcome!
April, 2016
- Jie's paper was accepted by Molecular Cell, congratulations!
April, 2016
- New postdoc position opening.
- Jie's co-first authorship manuscript is under revision at Molecular Cell (IF 14), fingers crossed!
December, 2015
- Kaifu's new manuscript was accepted to the Nucleic Acids Research, thank Alin for his help with the revision work!
- A manuscript was accepted to the Molecular and Cellular Biology, thank Dongyu for his help with the revision work!
November, 2015
- Dr. Jie Lu has joined us as postdoctoral Fellow, welcome onboard!
October, 2015
- Dr. Dongyu Zhao has joined us as postdoctoral Fellow, welcome onboard!
September, 2015
- Our Broad H3K4me3 research work is highlighted by the Cancer Discovery journal (IF 20.26)
- Dr. Alin Tomonaga has joined us as postdoctoral Fellow, welcome onboard!
August, 2015
- Kaifu's data-revisiting paper is accepted to Nature Genetics, we find that conserved broad H3K4me3 uniquely marks tumor suppressor in normal cell types.
- Kaifu's new manuscript is under the 3rd round review at Nature Genetics now.
- Kaifu's MeCP2 mCH-binding paper (with Dr. Zoghbi lab) has been accepted to PNAS.
