Chien

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Welcome to the '''Chien lab''' at the '''University of Massachusetts, Amherst''' in the '''Department of Biochemistry and Molecular Biology'''. <br>
Welcome to the '''Chien lab''' at the '''University of Massachusetts, Amherst''' in the '''Department of Biochemistry and Molecular Biology'''. <br>
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We are an interdisciplinary lab focused on understanding regulated protein degradation and quality control using biochemistry, structural biology and cell biology.  Our primary approach is to use both molecular and cellular techniques to understand the mechanisms that lead to specific substrate processing during basic cellular events.  We draw from several fields, including '''Microbiology''' and '''Biochemistry''', and are always interested in enthusiastic students who are driven to understand fundamental biological questions.  We are part of the MCB graduate program [http://www.bio.umass.edu/mcb/], the Chemistry-Biology Interface Program [http://www.umass.edu/cbi/], and the Institute for Cellular Engineering [http://www.umass.edu/ice/] here at UMass. Please see the other links above for more detailed information, or feel free to email if you have questions that aren't addressed.
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We are an interdisciplinary lab focused on understanding regulated protein degradation and quality control using biochemistry, structural biology and cell biology.  Our primary approach is to use both molecular and cellular techniques to understand the mechanisms that lead to specific substrate processing during basic cellular events.  We draw from several fields, including '''Biochemistry'''[http://www.biochem.umass.edu/] and '''Microbiology''' [http://www.bio.umass.edu/micro/], and are always interested in enthusiastic students who are driven to understand fundamental biological questions.  We are part of the MCB graduate program [http://www.bio.umass.edu/mcb/], the Chemistry-Biology Interface Program [http://www.umass.edu/cbi/], and the Institute for Cellular Engineering [http://www.umass.edu/ice/] here at UMass. Please see the other links above for more detailed information, or feel free to email if you have questions that aren't addressed.
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'''Hot News!!!''' <br>
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'''Lab Highlights''' <br>
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September 3, 2010. '''Claudine Mapa''' has received a Commonwealth College Research FellowshipCongratulations Claudine!! <br>
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August 1, 2013. '''Jing Liu''' is a co-author on our newly published Cell paper with the Laub Lab.Paper is available '''here''' [http://www.cell.com/abstract/S0092-8674(13)00773-3]Congrats Jing and Kristina! <br>  
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September 17, 2010.  '''Jing Liu''' and '''Keith Ballard''', both MCB graduate students, are rotating in the lab. Welcome Jin and Keith! <br>
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May 7, 2013.  '''Nowsheen Bhat's''' ClpP trapping paper is published in Molecular Microbiology!  Congratulations Nowsheen, Rob, Patrick, and Brian! <br>
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October 1, 2010.  '''Laura Francis''' has just joined the lab as a postdoctoral scholarWelcome Laura! <br>
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January 29, 2013.  '''Amber Cantin's''' paper (in collaboration with the Laub Lab at MIT) was accepted at Molecular Microbiology! Congrats Amber! <br>
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December 24, 2010. '''Joanne Lau''' was just awarded a very competitive CBI TraineeshipHuge Congratulations Joanne!<br>
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January 15, 2013.  '''Paula Muhlnickel''' returned to Ruhr University for the remainder of her Master's Diploma - We will miss you! <br>
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December 12, 2012'''Ying Zhang''' was awarded a Commonwealth College Honors Research Grant! Congrats Ying! <br>
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December 3, 2012. '''Jing Liu''' was awarded a CBI Training FellowshipCongrats Jing! <br>
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August 30, 2012.  '''Amber Cantin''' graduated with her Master's and accepted a job at NIBR, Cambridge. <br>
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June 15, 2012.  '''Amber Cantin''' won one of two '''Best Poster''' prizes at the Annual UMass Amherst/Worcester Biochemistry Retreat.  Congrats Amber! <br>
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June 7, 2012.  Keith Rood's paper on structural aspects of PdeA degradation was published online in Structure.  Check out the '''press release''' [http://www.umass.edu/loop/content/biochemists-id-crucial-recognition-tag-cellular-‘garbage-disposal’].  The paper is available '''here''' [http://www.cell.com/structure/abstract/S0969-2126(12)00178-5]. <br>
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May 3, 2011.  '''Patrick Stoddard''' was awarded an HHMI Summer Research Internship.  Congratulations Patrick! <br>
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May 11, 2012'''Claudine Mapa''', '''Patrick Stoddard''', and '''Marty Susskind''' graduated!  Claudine's headed to UMass Worcester for grad school.  Patrick's off to HarvardMarty's going to go tear up the west coast! Best of luck Guys! <br>
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May 3, 2011.  '''Claudine Mapa''' was awarded a Jessica Hayes Scholarship for her academic achievements and service to the communityCongrats Claudine! <br>
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[[Image:ChienLabSENIORSphoto.JPG|400px]] <br>
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September 1, 2011. '''Keith Rood''' was awarded his Masters for his thesis on adaptor mediated degradation by ClpXPWe'll miss you Keith! <br>
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May 4, 2012. '''Claudine Mapa''' presented his Capstone WorkCongrats Claudine! <br>
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September 1, 2011. '''Laura Francis''' joined the UMass Biology Department as a lecturer.  Congratulations Laura - come by often! <br>  
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April 27, 2012. '''Marty Susskind''' presented his Capstone Work.  Congratulations Marty!! <br>
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September 19, 2011. '''Kamal Kishore Jamal''', MCB student, is rotating in the lab for the Fall. Welcome Kamal! <br>
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April, 2012. '''Joanne Lau''' was selected to present her work at the Caulobacter Meeting and the ASM Prok Dev Meeting in Montreal! Congrats Joanne! <br>
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September 19, 2011. '''Ying Zhang''' and '''Daniel DiCorpo''' are new undergraduates in the lab.  Welcome Ying and Daniel! <br>
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February, 2012. '''Ying Qi Zhang''' was awarded a Slakey Award to perform summer research in the lab.  Congrats Ying! <br>
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September 19, 2011. '''Siddheshwari Advani''', MCB student, is rotating in the lab for the Fall.  Welcome Sid! <br>
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Revision as of 13:28, 1 August 2013

Home        Contact        Internal        Lab Members        Publications        Research        Talks       


Welcome to the Chien lab at the University of Massachusetts, Amherst in the Department of Biochemistry and Molecular Biology.

We are an interdisciplinary lab focused on understanding regulated protein degradation and quality control using biochemistry, structural biology and cell biology. Our primary approach is to use both molecular and cellular techniques to understand the mechanisms that lead to specific substrate processing during basic cellular events. We draw from several fields, including Biochemistry[1] and Microbiology [2], and are always interested in enthusiastic students who are driven to understand fundamental biological questions. We are part of the MCB graduate program [3], the Chemistry-Biology Interface Program [4], and the Institute for Cellular Engineering [5] here at UMass. Please see the other links above for more detailed information, or feel free to email if you have questions that aren't addressed.


Lab Highlights
August 1, 2013. Jing Liu is a co-author on our newly published Cell paper with the Laub Lab.Paper is available here [6]. Congrats Jing and Kristina!
May 7, 2013. Nowsheen Bhat's ClpP trapping paper is published in Molecular Microbiology! Congratulations Nowsheen, Rob, Patrick, and Brian!
January 29, 2013. Amber Cantin's paper (in collaboration with the Laub Lab at MIT) was accepted at Molecular Microbiology! Congrats Amber!
January 15, 2013. Paula Muhlnickel returned to Ruhr University for the remainder of her Master's Diploma - We will miss you!
December 12, 2012. Ying Zhang was awarded a Commonwealth College Honors Research Grant! Congrats Ying!
December 3, 2012. Jing Liu was awarded a CBI Training Fellowship! Congrats Jing!
August 30, 2012. Amber Cantin graduated with her Master's and accepted a job at NIBR, Cambridge.
June 15, 2012. Amber Cantin won one of two Best Poster prizes at the Annual UMass Amherst/Worcester Biochemistry Retreat. Congrats Amber!
June 7, 2012. Keith Rood's paper on structural aspects of PdeA degradation was published online in Structure. Check out the press release [7]. The paper is available here [8].

May 11, 2012. Claudine Mapa, Patrick Stoddard, and Marty Susskind graduated! Claudine's headed to UMass Worcester for grad school. Patrick's off to Harvard. Marty's going to go tear up the west coast! Best of luck Guys!

May 4, 2012. Claudine Mapa presented his Capstone Work. Congrats Claudine!
April 27, 2012. Marty Susskind presented his Capstone Work. Congratulations Marty!!
April, 2012. Joanne Lau was selected to present her work at the Caulobacter Meeting and the ASM Prok Dev Meeting in Montreal! Congrats Joanne!
February, 2012. Ying Qi Zhang was awarded a Slakey Award to perform summer research in the lab. Congrats Ying!

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