ColinWikholm BIOL368 Week 8
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Preparation for Week 9 Journal Club
Unknown Vocabulary
- chemokine receptors
- "receptors are G protein-coupled receptors containing 7 transmembrane domains that are found predominantly on the surface of leukocytes." (http://encyclopedia.thefreedictionary.com/chemokine+receptors)
- haemagglutinin
- "an antibody that causes the clumping of red blood cells" (http://www.thefreedictionary.com/haemagglutinin)
- prolate
- "Having the shape of a spheroid generated by rotating an ellipse about its longer axis." (http://www.thefreedictionary.com/prolate)
- ternary
- "consisting of three or groups of three" (http://www.thefreedictionary.com/ternary)
- complementarity-determining region
- " are regions within antibodies (also known as immunoglobulins) or T cell receptors where these proteins complement an antigen's shape. Thus, CDRs determine the protein's avidity (roughly, bonding strength) and specificity for specific antigens." (http://encyclopedia.thefreedictionary.com/Complementarity-determining+regions)
- metastable
- "Of, relating to, or being an unstable but relatively long-lived state of a chemical or physical system, as of a supersaturated solution or an excited atom." (http://www.thefreedictionary.com/metastable)
- ectodomain
- "An ectodomain is the domain of a membrane protein that extends into the extracellular space (the space outside a cell)." (http://encyclopedia.thefreedictionary.com/ectodomain"
- cryostat
- " is a device used to maintain low cryogenic temperatures of samples or devices mounted within the cryostat." (http://encyclopedia.thefreedictionary.com/cryostat)
- prophylactic
- "Acting to defend against or prevent something, especially disease; protective" (http://www.thefreedictionary.com/prophylactic)
- monoclonal antibody
- "Any of the highly specific antibodies produced in large quantity by the clones of a single hybridoma cell." (http://www.thefreedictionary.com/monoclonal+antibody)
This CD4-induced exposure is indicated by the enhanced binding of several gp120 antibodies18,19 which, like V3-loop antibodies, efficiently block the binding of gp120–CD4 complexes to the chemokine receptor
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Bioinfomatics Lab: Fall 2016
Class Page: BIOL 368-01: Bioinfomatics Laboratory, Fall 2016
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