Computational Biology/Gene Expression modeling/Stochastic Approach
From OpenWetWare
Modeling resources dealing with Stochastic Gene Expression
Models described in literature
Parameters used in literature
| Event modeled | Value / Range | Unit | Part / Organism | Experimental validation | Author / Year | Reference |
|---|---|---|---|---|---|---|
| Transcription initiation | [0.0025 - 0.2] | s-1 | generic | no | Thattai et al, 2001 | article |
| interval between transcription initiations | 3.3 | s | Lac Operon, E.Coli | Yes | Kennell et al, 1977 | article |
| next event | [0.01 - 0.1] | s-1 | not defined | no | Dr Doc | link |
mRNA degradation
| Event modeled | Value / Range | Unit | Part / Organism | Experimental validation | Author / Year | Reference |
|---|---|---|---|---|---|---|
| mRNA half-life | 2 | min | generic | no | Thattai et al, 2001 | article |
| next event | 0.01 - 0.1 | s-1 | not defined | no | Dr Doc | link |
| Event modeled | Value / Range | Unit | Part / Organism | Experimental validation | Author / Year | Reference |
|---|---|---|---|---|---|---|
| Translation initiation | [0.028-0.231] | generic | no | Thattai et al, 2001 | article | |
| Translation burst | 40 | molecules/mRNA | Lac Operon, E.Coli | Yes | Kennell et al, 1977 | article |
| next event | 0.01 - 0.1 | s-1 | not defined | no | Dr Doc | link |
Protein degradation
| Event modeled | Value / Range | Unit | Part / Organism | Experimental validation | Author / Year | Reference |
|---|---|---|---|---|---|---|
| Protein half-life | [15-120] | min | generic | no | Thattai et al, 2001 | article |
| next event | 0.01 - 0.1 | s-1 | not defined | no | Dr Doc | link |
