Conor Keith Week 6
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Purpose
- The purpose of this assignment is to construct a hypothesis regarding the effect of ammonia feed rate on a quantity of interest. The quantity of interest in my case is cytosolic alpha-ketoglutarate.
Workflow
- For this assignment, I read the two articles by van Riel et al, and the article by ter Schure et al. I took notes as I read the papers, trying to find a connection between the 40 mM ammonia pulse used in the experiment and cytosolic alpha-ketoglutarate. I noticed that levels of cytosolic alpha-ketoglutarate increased with the ammonia pulse. I then constructed a system of differential equations that I believe model the connection between the ammonia pulse and cytosolic alpha-ketoglutarate. The system contains three equations; one describing the change in ammonia concentration, one describing the change in biomass, and one describing the change in cytosolic alpha-ketoglutarate.
Results
Problem 1
- I chose the central nitrogen metabolism process project for my model.
Problem 2
- I read all 3 of the papers under the central nitrogen metabolism process section. Most of my focus was centered on the Structured, Minimal Parameter paper.
Problem 3
- Hypothesis: An increase in ammonia feed concentration via ammonia pulse will result in higher levels of cytosolic alpha-ketoglutarate.
Problem 4
- State variables:
- c=external ammonia concentration mM
- [math]\displaystyle{ \alpha }[/math]=cytosolic alpha-ketoglutarate [math]\displaystyle{ \mu }[/math]mol[math]\displaystyle{ \cdot }[/math]g[math]\displaystyle{ X^{-1} }[/math]
- X=biomass g[math]\displaystyle{ \cdot }[/math]l^-1
Conclusion
Acknowledgements
References
Assignment Pages:
- Week 1 Assignment
- Week 2 Assignment
- Week 3 Assignment
- Week 4 Assignment
- Week 5 Assignment
- Week 6 Assignment
- Week 7 Assignment
- Week 9 Assignment
- Week 10 Assignment
- Week 11 Assignment
- Week 12 Assignment
- Week 14/15 Assignment
Individual Journal Entries :
- Conor Keith Week 2
- Conor Keith Week 3
- Conor Keith Week 4
- Conor Keith Week 5
- Conor Keith Week 6
- Conor Keith Week 7
- Conor Keith Week 9
- Conor Keith Week 10
- Conor Keith Week 11
- Conor Keith Week 12
- Conor Keith Week 14/15
Shared Journal Pages:
