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==Personal Info==


=Personal Info=
[[Image:davidgmiguez.jpg|160 px|left|David G. Míguez]]
''Current position:'' Marie Curie fellow at Elisa Martí's Lab. Instituto de Biologia Molecular de Barcelona, CISC.
 
Head of the [http://sysbio.openwetware.org/  Biophysics and Systems Biology Lab  ]
 
Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, 28049 Madrid
 
 
''Previous Research Institutions'': 
 
*2001-2005 PhD Thesis at Group of Nonlinear Physics at Santiago de Compostela (Galicia, Spain),
 
*2005-2006 Group of Complex Systems, Brandeis University (MA)
 
*2006-2009  Department of Systems Biology, Harvard Medical School (MA),
 
*2009-2011 Instituto de Biología Molecular de Barcelona (CSIC, Spain)


''Background:'' Nonlinear Dynamics, reaction-diffusion, autocatalitic and bistable systems, feedback, pH oscillators, Turing Patterns, Enzyme kinetics, Systems Biology in Cancer, Signaling pathways.  
''Background:'' Nonlinear Dynamics, reaction-diffusion, autocatalitic and bistable systems, feedback, pH oscillators, Turing Patterns, Enzyme kinetics, Systems Biology in Cancer, Signaling pathways.  


''Interest:'' Development of Central Nervous System in Vertebrates
''Interests:'' Systems Biology, Biophysics


=Contact=
Editor of [http://www.iospress.nl/journal/in-silico-biology/ In Silico Biology]
 
==Contact==


David G. Míguez
David G. Míguez


e-mail: davidgmiguez ''AT'' gmail DOT com
e-mail: david DOT gomez DOT miguez ''AT'' uam DOT es
 
Personal Web: http://silver.med.harvard.edu/david/
 
Blog: http://www.universonica.net


Instituto de Biologia Molecular de Barcelona, CSIC
Depto. de Fisica de la Materia Condensada
Parc Cientific de Barcelona
Facultad de Ciencias
C/Baldiri i Reixac 15-21
Universidad Autonoma de Madrid
Barcelona 08028
Cantoblanco,
28049 Madrid (SPAIN)


phone 34-657-929-775
phone (+34) 657-929-775
fax 34-93-4034979
work  (+34) 914-978-076


=Publications=
==Publications==
# D. G. Míguez, ''The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio'' (submitted).
# P. Gregorio-Godoy, D. G. Míguez, Synthetic ''Approaches to Study Transcriptional Networks and Noise in Mammalian Systems'', IET Systems Biology (in press).
# D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, ''On the Interaction Of Chemical Patterns in Coupled Layers'' (submitted).
# D. G. Míguez,  ''Network Nonlinearities in Drug Treatment'', Interdisciplinary Sciences: Computational Life Sciences (in press).
# D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, "Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium", Phys. Rev. E, '''80''', 026208 (2009).
# V. Doldán-Martelli, R. Guantes, D. G. Míguez, ''[http://www.nature.com/psp/journal/v2/n2/full/psp20132a.html  A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies]'', CPT: Pharmacometrics & Systems Pharmacology '''2''', e26 (2013).
# I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, "Intron length increases oscillatory periods of gene expression in animal cells", Genes & Dev., '''22''' 2008, 2342-2346 (2008).
# V. Doldán-Martelli, D. G. Míguez, ''Theoretical Approaches to Growth Hormone Signaling'', in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J.  Anderssen Nova Publishers ISBN 9781619426818 (2012).
# S. Alonso, D. G. Míguez, F. Sagués, “Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium”, Europhys. Lett, '''81''', 30006 (2008).  
# D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v84/i4/e046210 Interaction Of Chemical Patterns in Coupled Layers]'', Phys. Rev. E, '''84''', 046210 (2011).
# D. G. Míguez, V. K. Vanag, I. R. Epstein, “Fronts and pulses in an enzymatic reaction with glucose oxidase" P.N.A.S. '''104''', 6992 (2007).
# D. G. Míguez, ''[http://www.sciencedirect.com/science/article/pii/S0301462210000402 The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio]''  Biophys Chem '''148''', 74-81 (2010)
# V. K. Vanag, D.G. Míguez, I. R. Epstein, “Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR”, J. Phys. Chem. '''125''', 194515 (2006).
# D.G. Míguez, ''Forcing of Nonlinear Pattern Formation Systems'',  Lambert Academic Publishing, ISBN 9783838364223 (2010) [http://www.amazon.com/Forcing-Nonlinear-Pattern-Formation-Systems/dp/3838364228 Book].
# D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, “Turing patterns of oscillating spots”, Phys. Rev. Lett, '''97''', 178301 (2006).  
# D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, ''[http://pre.aps.org/abstract/PRE/v80/i2/e026208 Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium]'', Phys. Rev. E, '''80''', 026208 (2009).
# D. G. Míguez, A. P. Muñuzuri,“On the orientation of stripes in fish skin patterning”, Biophys. Chem. '''124''', 161 (2006).  
# I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, ''[http://genesdev.cshlp.org/content/22/17/2342.full Intron length increases oscillatory periods of gene expression in animal cells]'', Genes & Dev., '''22''' 2008, 2342-2346 (2008).
# D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, "Experimental steady pattern formation in reaction-diffusion-advection systems", Phys. Rev. E '''73''', 025201 (R) (2006).
# S. Alonso, D. G. Míguez, F. Sagués, ''[http://iopscience.iop.org/0295-5075/81/3/30006 Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium]'', Europhys. Lett, '''81''', 30006 (2008).  
# D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, "Effect of Axial Growth on Turing Pattern Formation".  Phys. Rev. Lett '''96''', 048304 (2006).
# D. G. Míguez, V. K. Vanag, I. R. Epstein, ''[http://www.pnas.org/content/104/17/6992.full Fronts and pulses in an enzymatic reaction with glucose oxidase]'' P.N.A.S. '''104''', 6992 (2007).
# D. G. Míguez, G. Izús, A. P. Muñuzuri, "Robustness and Stability of Flow-and-Diffusion Structures", Phys. Rev. E '''73''', 016207 (2006).
# V. K. Vanag, D.G. Míguez, I. R. Epstein, ''[http://jcp.aip.org/resource/1/jcpsa6/v125/i19/p194515_s1 Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR]'', J. Phys. Chem. '''125''', 194515 (2006).
# D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, "Turing instability controlled by spatiotemporal imposed dynamics", Phys. Rev. E '''71''', 066217 (2005).
# D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, ''[http://prl.aps.org/abstract/PRL/v97/i17/e178301 Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction]'', Phys. Rev. Lett, '''97''', 178301 (2006).  
# F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, "Spatio-Temporal Forcing of Turing Patterns", Physica D '''199''', 235 (2004) .
# D. G. Míguez, A. P. Muñuzuri, ''[http://www.sciencedirect.com/science/article/pii/S0301462206002122 On the orientation of stripes in fish skin patterning]'', Biophys. Chem. '''124''', 161 (2006).  
# D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, "Traveling-Stripe Forcing Generates Hexagonal Patterns", Phys. Rev. Lett. '''93''', 048303 (2004) .
# D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v73/i2/e025201 Experimental steady pattern formation in reaction-diffusion-advection systems]'', Phys. Rev. E '''73''', 025201 (R) (2006).
# M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, "Control of chemical pattern formation by a clock-and-wavefront type mechanism", Biophys. Chem. '''110''', 231 (2004). '''Shared 1st authorship'''.
# D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, ''[http://prl.aps.org/abstract/PRL/v96/i4/e048304 Effect of Axial Growth on Turing Pattern Formation]''.  Phys. Rev. Lett '''96''', 048304 (2006).
# B. Peña, C. Pérez-García, A. Sanz-Anchelergues, "Transverse instabilities in chemical Turing patterns of stripes", D. G. Míguez, A. P. Muñuzuri, Phys. Rev. E '''68''', 056206 (2003) .
# D. G. Míguez, G. Izús, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v73/i1/e016207 Robustness and Stability of Flow-and-Diffusion Structures]'', Phys. Rev. E '''73''', 016207 (2006).
# S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, "Dynamics of Turing Patterns under Spatiotemporal Forcing", Phys. Rev. Lett '''90''', 128301 (2003).
# D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, ''[http://pre.aps.org/abstract/PRE/v71/i6/e066217 Turing instability controlled by spatiotemporal imposed dynamics]'', Phys. Rev. E '''71''', 066217 (2005).
# F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, ''[http://www.sciencedirect.com/science/article/pii/S0167278904003197 Travelling-stripe forcing of Turing patterns]'', Physica D '''199''', 235 (2004).
# D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, ''[http://prl.aps.org/abstract/PRL/v93/i4/e048303 Traveling-Stripe Forcing Generates Hexagonal Patterns]'', Phys. Rev. Lett. '''93''', 048303 (2004).
# M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, ''[http://www.sciencedirect.com/science/article/pii/S030146220400078X Control of chemical pattern formation by a clock-and-wavefront type mechanism]'', Biophys. Chem. '''110''', 231 (2004). '''Shared 1st authorship'''.
# B. Peña, C. Pérez-García, A. Sanz-Anchelergues, D. G. Míguez, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v68/i5/e056206 Transverse instabilities in chemical Turing patterns of stripes]'',  Phys. Rev. E '''68''', 056206 (2003).
# S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, ''[http://prl.aps.org/abstract/PRL/v90/i12/e128301 Dynamics of Turing Patterns under Spatiotemporal Forcing]'', Phys. Rev. Lett '''90''', 128301 (2003).


Updated by: [[User:DavidMiguez|David]] 12:26, 21 December 2009 (EST)
[[User:DavidMiguez|David]] 12:38, 14 February 2013 (EST)

Revision as of 04:30, 18 February 2013

Personal Info

David G. Míguez
David G. Míguez

Head of the Biophysics and Systems Biology Lab

Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, 28049 Madrid


Previous Research Institutions:

  • 2001-2005 PhD Thesis at Group of Nonlinear Physics at Santiago de Compostela (Galicia, Spain),
  • 2005-2006 Group of Complex Systems, Brandeis University (MA)
  • 2006-2009 Department of Systems Biology, Harvard Medical School (MA),
  • 2009-2011 Instituto de Biología Molecular de Barcelona (CSIC, Spain)

Background: Nonlinear Dynamics, reaction-diffusion, autocatalitic and bistable systems, feedback, pH oscillators, Turing Patterns, Enzyme kinetics, Systems Biology in Cancer, Signaling pathways.

Interests: Systems Biology, Biophysics

Editor of In Silico Biology

Contact

David G. Míguez

e-mail: david DOT gomez DOT miguez AT uam DOT es

Depto. de Fisica de la Materia Condensada Facultad de Ciencias Universidad Autonoma de Madrid Cantoblanco, 28049 Madrid (SPAIN)

phone (+34) 657-929-775 work (+34) 914-978-076

Publications

  1. P. Gregorio-Godoy, D. G. Míguez, Synthetic Approaches to Study Transcriptional Networks and Noise in Mammalian Systems, IET Systems Biology (in press).
  2. D. G. Míguez, Network Nonlinearities in Drug Treatment, Interdisciplinary Sciences: Computational Life Sciences (in press).
  3. V. Doldán-Martelli, R. Guantes, D. G. Míguez, A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies, CPT: Pharmacometrics & Systems Pharmacology 2, e26 (2013).
  4. V. Doldán-Martelli, D. G. Míguez, Theoretical Approaches to Growth Hormone Signaling, in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J. Anderssen Nova Publishers ISBN 9781619426818 (2012).
  5. D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, Interaction Of Chemical Patterns in Coupled Layers, Phys. Rev. E, 84, 046210 (2011).
  6. D. G. Míguez, The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio Biophys Chem 148, 74-81 (2010)
  7. D.G. Míguez, Forcing of Nonlinear Pattern Formation Systems, Lambert Academic Publishing, ISBN 9783838364223 (2010) Book.
  8. D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium, Phys. Rev. E, 80, 026208 (2009).
  9. I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, Intron length increases oscillatory periods of gene expression in animal cells, Genes & Dev., 22 2008, 2342-2346 (2008).
  10. S. Alonso, D. G. Míguez, F. Sagués, Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium, Europhys. Lett, 81, 30006 (2008).
  11. D. G. Míguez, V. K. Vanag, I. R. Epstein, Fronts and pulses in an enzymatic reaction with glucose oxidase P.N.A.S. 104, 6992 (2007).
  12. V. K. Vanag, D.G. Míguez, I. R. Epstein, Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR, J. Phys. Chem. 125, 194515 (2006).
  13. D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction, Phys. Rev. Lett, 97, 178301 (2006).
  14. D. G. Míguez, A. P. Muñuzuri, On the orientation of stripes in fish skin patterning, Biophys. Chem. 124, 161 (2006).
  15. D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, Experimental steady pattern formation in reaction-diffusion-advection systems, Phys. Rev. E 73, 025201 (R) (2006).
  16. D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, Effect of Axial Growth on Turing Pattern Formation. Phys. Rev. Lett 96, 048304 (2006).
  17. D. G. Míguez, G. Izús, A. P. Muñuzuri, Robustness and Stability of Flow-and-Diffusion Structures, Phys. Rev. E 73, 016207 (2006).
  18. D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, Turing instability controlled by spatiotemporal imposed dynamics, Phys. Rev. E 71, 066217 (2005).
  19. F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, Travelling-stripe forcing of Turing patterns, Physica D 199, 235 (2004).
  20. D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, Traveling-Stripe Forcing Generates Hexagonal Patterns, Phys. Rev. Lett. 93, 048303 (2004).
  21. M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, Control of chemical pattern formation by a clock-and-wavefront type mechanism, Biophys. Chem. 110, 231 (2004). Shared 1st authorship.
  22. B. Peña, C. Pérez-García, A. Sanz-Anchelergues, D. G. Míguez, A. P. Muñuzuri, Transverse instabilities in chemical Turing patterns of stripes, Phys. Rev. E 68, 056206 (2003).
  23. S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, Dynamics of Turing Patterns under Spatiotemporal Forcing, Phys. Rev. Lett 90, 128301 (2003).

David 12:38, 14 February 2013 (EST)

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