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Revision as of 20:08, 23 May 2007


<font face="trebuchet ms" style="color:#ffffff"> Home </font> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <font face="trebuchet ms" style="color:#ffffff"> Contact </font> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <font face="trebuchet ms" style="color:#ffffff"> Internal </font> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <font face="trebuchet ms" style="color:#ffffff"> Lab Members </font> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <font face="trebuchet ms" style="color:#ffffff"> Publications </font> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <font face="trebuchet ms" style="color:#ffffff"> Research </font> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <font face="trebuchet ms" style="color:#ffffff"> Talks </font> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </center> </div><br>


Contents

Recent Publications

<font face=Verdana>


<p>Bu P, Evrard YA, Lozano G <b>Dent SY.</b> (2007) Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos. Mol Cell Biol. 2007 Feb 26; [Epub ahead of print]. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17325035&query_hl=1&itool=pubmed_docsum>Abstract</a></p>

<p>Malave TM, <b>Dent SY.</b> (2006) Transcriptional repression by Tup1-Ssn6. Biochem Cell Biol. 2006 Aug;84(4):437-43. Review. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16936817&query_hl=1&itool=pubmed_docsum>Abstract</a></p>

<p>Lin W, <b>Dent SY.</b> (2006) Functions of histone-modifying enzymes in development. Curr Opin Genet Dev. 2006 Apr;16(2):137-42. Review. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16503130&query_hl=1&itool=pubmed_docsum>Abstract</a></p>

<p>Davie JK, <b>Dent SY.</b> (2006) No Spt6, no nucleosomes, no activator required. Mol Cell. Feb 17;21(4):452-3. Preview. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16483927&query_hl=1&itool=pubmed_docsum>Abstract</a></p>

<p>Tripic T, Edmondson DG, Davie JK, Strahl BD, <b>Dent SY.</b> (2006) The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation. Biochem Biophys Res Commun. Jan 20;339(3):905-14. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16329992&query_hl=1&itool=pubmed_docsum>Abstract</a></p>

<p>Zhang K, <b>Dent SY.</b> (2005)

Histone modifying enzymes and cancer: going beyond histones.

J Cell Biochem. Dec 15;96(6):1137-48. Review. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16173079&query_hl=1&itool=pubmed_docsum>Abstract</a></p>

<p>Zhang K, Lin W, Latham JA, Riefler GM, Schumacher JM, Chan C, Tatchell K, Hawke DH, Kobayashi R, <b>Dent SY.</b> (2005)

The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation.

Cell. Sep 9;122(5):723-34. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16143104&query_hl=8">Abstract</a></p>

<p>Phan HM, Xu AW, Coco C, Srajer G, Wyszomierski S, Evrard YA, Eckner R, <b>Dent SY.</b> (2005)

GCN5 and p300 share essential functions during early embryogenesis.

Dev Dyn. Aug; 233(4):1337-47. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15937931&query_hl=1&itool=pubmed_docsum>Abstract</a></p>

<p>Davie JK <b>Dent SY.</b> (2004)

Histone modifications in corepressor functions.

Curr Top Dev Biol. 59:145-63. Review. No abstract available.</p>

<p>Coombes MM, Briggs KL, Bone JR, Clayman GL, El-Naggar AK, <b>Dent SY.</b> (2003) Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation. Oncogene. Dec 4;22(55):8902-11. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14654786">Abstract</a></p>

<p>Davie JK, Edmondson DG, Coco CB, <b>Dent SY</b>. (2003) Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo. J Biol Chem. 2003 Oct 2 [Epub ahead of print] <a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14525981&dopt=Abstract">Abstract</a><br><a href="Protocols/oligo_davie_jbc.html"><i><b><font size=2>Oligos</b> used in paper</font></i></a></p>

<p>Liu X, Tesfai J, Evrard YA, <b>Dent SY</b>, Martinez E. (2003) c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation. J Biol Chem. May 30;278(22):20405-12. <a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12660246&dopt=Abstract">Abstract</a></p>

<p>Mukai Y, Davie JK, <b>Dent SY.</b> (2003) Physical and functional interaction of the yeast corepressor Tup1 with mRNA 5'-triphosphatase. J Biol Chem. May 23;278(21):18895-901<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12637515&dopt=Abstract">Abstract</a></p>

<p>Edmondson DG, Davie JK, Zhou J, Mirnikjoo B, Tatchell K, <b>Dent SY.</b> (2002) Site-specific loss of acetylation upon phosphorylation of histone H3. J Biol Chem. Aug 16;277(33):29496-502. <a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12039950&dopt=Abstract">Abstract</a></p>

<p> Davie JK, <b>Dent SY.</b> (2002) Transcriptional control: an activating role for arginine methylation. Curr Biol. Jan 22;12(2):R59-61.<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11818080&dopt=Abstract">Abstract</a> </p>

<p>Davie JK, Trumbly RJ, <b>Dent SY.</b> (2002) Histone-dependent association of Tup1-Ssn6 with repressed genes in vivo. Mol Cell Biol.Feb;22(3):693-703.<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11784848&dopt=Abstract">Abstract</a></p>

<p>Briggs SD, Bryk M, Strahl BD, Cheung WL, Davie JK, <b>Dent SY</b>, Winston F, Allis CD.(2001) Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae. Genes Dev. Dec 15;15(24):3286-95.<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11751634&dopt=Abstract">Abstract</a></p>

<p><b>Roth SY</b>, Denu JM, Allis CD. (2001) Histone acetyltransferases. Annu Rev Biochem. ;70:81-120. Review.<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11395403&dopt=Abstract">Abstract</a></p>

<p>Marmorstein R, <b>Roth SY.</b> (2001) Histone acetyltransferases: function, structure, and catalysis. Curr Opin Genet Dev. Apr;11(2):155-61. Review..<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11250138&dopt=Abstract">Abstract</a></p>

<p>Bone, J.R. and <b>Roth, S.Y.</b> (2001) Recruitment of the yeast Tup1-Ssn6 repressor is associated with localized decreases in histone acetylation. J. Biol. Chem. 276: 1808-1813<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11056171&dopt=Abstract">Abstract</a></p>

<p>Xu, W., Edmondson, D.E., Evrard, Y.A., Wakamiya, W., Behringer, R.R., and <b>Roth, S.Y.</b> (2000) Loss of GCN512 Leads to Increased Apoptosis and Mesodermal Defects During Mouse Development. Nature Genetics 26: 229-232.<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11017084&dopt=Abstract">Abstract</a></p>

<p>Watson, A.D., Edmondson, D.G., Bone, J.R., Mukai, Y., Yu, Y., Du, W., Stillman, D.J., and <b>Roth, S.Y.</b> (2000) Ssn6-Tup1 Interacts with Class I Histone Deacetylases Required for Repression. Genes Dev. 14: 2737-2744.<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11069890&dopt=Abstract">Abstract</a></p>

<p>Roth, D.B. and <b>Roth, S.Y.</b> (2000) Unequal access: Regulating V(D)J recombination through chromatin remodeling. Cell 103: 699-702.<a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11114326&dopt=Abstract">Abstract</a></p></span></font></td>

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