Drummond - Revision history

http://www.openwetware.org/index.php?title=Drummond&feed=atom&action=history Drummond - Revision history 2013-05-18T22:37:28Z Revision history for this page on the wiki MediaWiki 1.13.2 http://www.openwetware.org/index.php?title=Drummond&diff=607847&oldid=prev Dadrummond at 16:02, 15 June 2012 2012-06-15T16:02:51Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 16:02, 15 June 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 8:</td> <td colspan="2" class="diff-lineno">Line 8:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"><strong>We are [[Drummond:Employment|hiring]]!</strong></del></div></td><td colspan="2"> </td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=590271&oldid=prev Dadrummond at 00:41, 7 March 2012 2012-03-07T00:41:01Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:41, 7 March 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 8:</td> <td colspan="2" class="diff-lineno">Line 8:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>We are [[Drummond:Employment|hiring]]!</<del class="diffchange diffchange-inline">small</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"><strong></ins>We are [[Drummond:Employment|hiring]]!</<ins class="diffchange diffchange-inline">strong</ins>></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>--></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td></tr>  </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=590270&oldid=prev Dadrummond at 00:39, 7 March 2012 2012-03-07T00:39:09Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 00:39, 7 March 2012</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 8:</td> <td colspan="2" class="diff-lineno">Line 8:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">We are [[Drummond:Employment|hiring]]!</small></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline"> </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=564850&oldid=prev Dadrummond at 03:11, 7 November 2011 2011-11-07T03:11:33Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 03:11, 7 November 2011</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 4:</td> <td colspan="2" class="diff-lineno">Line 4:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>To carry out biological functions, a typical protein must fold into a complex structure encoded by its amino-acid sequence. Alterations of that sequence often cause misfolding, disrupting function and also creating toxic, aggregation-prone molecules.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>To carry out biological functions, a typical protein must fold into a complex structure encoded by its amino-acid sequence. Alterations of that sequence often cause misfolding, disrupting function and also creating toxic, aggregation-prone molecules.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Protein misfolding causes major human neurodegenerative diseases, shapes quality control mechanisms inside the cell, and <del class="diffchange diffchange-inline">appears to govern </del>how rapidly protein-coding genes accumulate sequence changes over evolutionary time. Yet strikingly little is known about the major causes, amounts, or consequences of protein misfolding. Key open questions include: What are the dominant causes of protein misfolding in normal <del class="diffchange diffchange-inline">and </del>disease-afflicted cells? What fraction of newly synthesized proteins misfold, and why? What is the error rate of protein synthesis? Why are misfolded proteins toxic?</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Protein misfolding causes major <ins class="diffchange diffchange-inline">age-related </ins>human neurodegenerative diseases, shapes quality control mechanisms inside the cell, and <ins class="diffchange diffchange-inline">influences </ins>how rapidly protein-coding genes accumulate sequence changes over evolutionary time. Yet strikingly little is known about the major causes, amounts, or consequences of protein misfolding. Key open questions include: What are the dominant causes of protein misfolding in normal<ins class="diffchange diffchange-inline">, </ins>disease-afflicted <ins class="diffchange diffchange-inline">and aging </ins>cells? What fraction of newly synthesized proteins misfold, and why? What is the error rate of protein synthesis? Why are misfolded proteins toxic<ins class="diffchange diffchange-inline">, and how do cells detect and respond to them</ins>?</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We seek answers to these questions, taking an integrated biochemical, genetic, and evolutionary approach.</div></td></tr>  </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=559357&oldid=prev Dadrummond at 21:49, 1 November 2011 2011-11-01T21:49:50Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 21:49, 1 November 2011</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 9:</td> <td colspan="2" class="diff-lineno">Line 9:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><hr/></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><small>Congratulations to Dr. Kerry Samerotte, winner of the [http://www.smbe.org/awards/the-walter-m-fitch-award/ 2011 Walter M. Fitch Award]<del class="diffchange diffchange-inline">!</del><br/></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><small>Congratulations to Dr. Kerry Samerotte, winner of the [http://www.smbe.org/awards/the-walter-m-fitch-award/ 2011 Walter M. Fitch Award]<ins class="diffchange diffchange-inline">.</ins><br/></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Read our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].<br/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>Read our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].<br/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Drummond:Employment|<del class="diffchange diffchange-inline">Join us</del>]]<del class="diffchange diffchange-inline">!</del></small></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">We are now </ins>[[Drummond:Employment|<ins class="diffchange diffchange-inline">hiring</ins>]]<ins class="diffchange diffchange-inline">.</ins></small></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td></tr>  </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=552388&oldid=prev Dadrummond: Rewrite 2011-10-26T03:53:26Z

<p>Rewrite</p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 03:53, 26 October 2011</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><div style="font-size: medium; width: 750px;"></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><div style="font-size: medium; width: 750px;"></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Image:Drummond-home-simple.jpg||right|]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Image:Drummond-home-simple.jpg||right|]]</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>To carry out biological functions, a typical protein must fold into a complex structure encoded by its amino-acid sequence. <del class="diffchange diffchange-inline">When DNA mutations or synthesis errors alter </del>that sequence, <del class="diffchange diffchange-inline">the protein may misfold, not only losing its </del>function <del class="diffchange diffchange-inline">but becoming a </del>toxic, aggregation-prone <del class="diffchange diffchange-inline">rogue</del>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>To carry out biological functions, a typical protein must fold into a complex structure encoded by its amino-acid sequence. <ins class="diffchange diffchange-inline">Alterations of </ins>that sequence <ins class="diffchange diffchange-inline">often cause misfolding</ins>, <ins class="diffchange diffchange-inline">disrupting </ins>function <ins class="diffchange diffchange-inline">and also creating </ins>toxic, aggregation-prone <ins class="diffchange diffchange-inline">molecules</ins>.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Protein misfolding <del class="diffchange diffchange-inline">profoundly shapes organism fitness (including human health): it is a cause of </del>major human diseases, <del class="diffchange diffchange-inline">a requirement for proper immune-system function</del>, and <del class="diffchange diffchange-inline">a potentially dominant regulator of </del>how rapidly protein-coding genes accumulate sequence changes over evolutionary time. Yet little is known about the major causes, amounts, or consequences of protein misfolding <del class="diffchange diffchange-inline">at </del>the <del class="diffchange diffchange-inline">scales </del>of <del class="diffchange diffchange-inline">whole genomes </del>and <del class="diffchange diffchange-inline">organisms.  </del>What fraction of newly synthesized proteins misfold, and why? <del class="diffchange diffchange-inline"> Are some classes </del>of <del class="diffchange diffchange-inline">proteins exceptionally robust to misfolding</del>? <del class="diffchange diffchange-inline">If so, what phenotypic consequences result from compromising that robustness</del>?</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Protein misfolding <ins class="diffchange diffchange-inline">causes </ins>major human <ins class="diffchange diffchange-inline">neurodegenerative </ins>diseases, <ins class="diffchange diffchange-inline">shapes quality control mechanisms inside the cell</ins>, and <ins class="diffchange diffchange-inline">appears to govern </ins>how rapidly protein-coding genes accumulate sequence changes over evolutionary time. Yet <ins class="diffchange diffchange-inline">strikingly </ins>little is known about the major causes, amounts, or consequences of protein misfolding<ins class="diffchange diffchange-inline">. Key open questions include: What are </ins>the <ins class="diffchange diffchange-inline">dominant causes </ins>of <ins class="diffchange diffchange-inline">protein misfolding in normal </ins>and <ins class="diffchange diffchange-inline">disease-afflicted cells? </ins>What fraction of newly synthesized proteins misfold, and why? <ins class="diffchange diffchange-inline">What is the error rate </ins>of <ins class="diffchange diffchange-inline">protein synthesis</ins>? <ins class="diffchange diffchange-inline">Why are misfolded proteins toxic</ins>?</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>We <del class="diffchange diffchange-inline">are exploring the scope</del>, <del class="diffchange diffchange-inline">scale</del>, and <del class="diffchange diffchange-inline">causes of protein misfolding and its effects on organism fitness, with a strong focus on newly synthesized proteins</del>. <del class="diffchange diffchange-inline">Using the yeast <i>Saccharomyces cerevisiae</del></<del class="diffchange diffchange-inline">i</del>> <del class="diffchange diffchange-inline">as a model system, our research combines evolutionary genomics, which reveals broad patterns of fitness imprinted in DNA, with system- and molecular-level misfolding studies designed to illuminate the conserved biochemistry underlying these patterns.</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>We <ins class="diffchange diffchange-inline">seek answers to these questions</ins>, <ins class="diffchange diffchange-inline">taking an integrated biochemical, genetic</ins>, and <ins class="diffchange diffchange-inline">evolutionary approach</ins>.</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><<ins class="diffchange diffchange-inline">hr</ins>/></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><small>Congratulations to Dr. Kerry Samerotte, winner of the [http://www.smbe.org/awards/the-walter-m-fitch-award/ 2011 Walter M. Fitch Award]!<br/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><small>Congratulations to Dr. Kerry Samerotte, winner of the [http://www.smbe.org/awards/the-walter-m-fitch-award/ 2011 Walter M. Fitch Award]!<br/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">In related news, check out </del>our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].<br/></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">Read </ins>our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].<br/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline">We're now </del>[[Drummond:Employment|<del class="diffchange diffchange-inline">hiring</del>]]!</small></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Drummond:Employment|<ins class="diffchange diffchange-inline">Join us</ins>]]!</small></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td></tr>  </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=544308&oldid=prev Dadrummond at 02:31, 5 October 2011 2011-10-05T02:31:39Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 02:31, 5 October 2011</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 9:</td> <td colspan="2" class="diff-lineno">Line 9:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><small>Congratulations to Dr. Kerry Samerotte, winner of the [http://www.smbe.org/awards/the-walter-m-fitch-award/ 2011 Walter M. Fitch Award]!<br/></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><small>Congratulations to Dr. Kerry Samerotte, winner of the [http://www.smbe.org/awards/the-walter-m-fitch-award/ 2011 Walter M. Fitch Award]!<br/></div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>In related news, check out our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].</small></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>In related news, check out our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].<ins class="diffchange diffchange-inline"><br/></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">We're now [[Drummond:Employment|hiring]]!</ins></small></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td></tr>  </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=529760&oldid=prev Dadrummond: Kerry prize 2011-08-15T21:51:41Z

<p>Kerry prize</p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 21:51, 15 August 2011</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 8:</td> <td colspan="2" class="diff-lineno">Line 8:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are exploring the scope, scale, and causes of protein misfolding and its effects on organism fitness, with a strong focus on newly synthesized proteins. Using the yeast <i>Saccharomyces cerevisiae</i> as a model system, our research combines evolutionary genomics, which reveals broad patterns of fitness imprinted in DNA, with system- and molecular-level misfolding studies designed to illuminate the conserved biochemistry underlying these patterns.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are exploring the scope, scale, and causes of protein misfolding and its effects on organism fitness, with a strong focus on newly synthesized proteins. Using the yeast <i>Saccharomyces cerevisiae</i> as a model system, our research combines evolutionary genomics, which reveals broad patterns of fitness imprinted in DNA, with system- and molecular-level misfolding studies designed to illuminate the conserved biochemistry underlying these patterns.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><small><del class="diffchange diffchange-inline">Check </del>out our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].</small></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><small><ins class="diffchange diffchange-inline">Congratulations to Dr. Kerry Samerotte, winner of the [http://www.smbe.org/awards/the-walter-m-fitch-award/ 2011 Walter M. Fitch Award]!<br/></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">In related news, check </ins>out our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html most recent paper in PNAS].</small></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td></tr>  </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=525895&oldid=prev Dadrummond at 10:48, 26 July 2011 2011-07-26T10:48:16Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 10:48, 26 July 2011</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 8:</td> <td colspan="2" class="diff-lineno">Line 8:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are exploring the scope, scale, and causes of protein misfolding and its effects on organism fitness, with a strong focus on newly synthesized proteins. Using the yeast <i>Saccharomyces cerevisiae</i> as a model system, our research combines evolutionary genomics, which reveals broad patterns of fitness imprinted in DNA, with system- and molecular-level misfolding studies designed to illuminate the conserved biochemistry underlying these patterns.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are exploring the scope, scale, and causes of protein misfolding and its effects on organism fitness, with a strong focus on newly synthesized proteins. Using the yeast <i>Saccharomyces cerevisiae</i> as a model system, our research combines evolutionary genomics, which reveals broad patterns of fitness imprinted in DNA, with system- and molecular-level misfolding studies designed to illuminate the conserved biochemistry underlying these patterns.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><small>Check out our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html <del class="diffchange diffchange-inline">new </del>paper in PNAS]<del class="diffchange diffchange-inline">!</del></small></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><small>Check out our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html <ins class="diffchange diffchange-inline">most recent </ins>paper in PNAS]<ins class="diffchange diffchange-inline">.</ins></small></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td></tr>  </table>

Dadrummond http://www.openwetware.org/index.php?title=Drummond&diff=484263&oldid=prev Dadrummond at 23:18, 8 January 2011 2011-01-08T23:18:21Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">←Older revision</td> <td colspan='2' style="background-color: white; color:black;">Revision as of 23:18, 8 January 2011</td> </tr> <tr><td colspan="2" class="diff-lineno">Line 7:</td> <td colspan="2" class="diff-lineno">Line 7:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are exploring the scope, scale, and causes of protein misfolding and its effects on organism fitness, with a strong focus on newly synthesized proteins. Using the yeast <i>Saccharomyces cerevisiae</i> as a model system, our research combines evolutionary genomics, which reveals broad patterns of fitness imprinted in DNA, with system- and molecular-level misfolding studies designed to illuminate the conserved biochemistry underlying these patterns.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>We are exploring the scope, scale, and causes of protein misfolding and its effects on organism fitness, with a strong focus on newly synthesized proteins. Using the yeast <i>Saccharomyces cerevisiae</i> as a model system, our research combines evolutionary genomics, which reveals broad patterns of fitness imprinted in DNA, with system- and molecular-level misfolding studies designed to illuminate the conserved biochemistry underlying these patterns.</div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><small>Check out our [http://www.pnas.org/content/early/2010/12/22/1017570108.full.pdf+html new paper in PNAS]!</small></ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></div></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>{{Drummond_Bottom}}</div></td></tr>  </table>

Dadrummond