Dziubla:Publications

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M. Howard, X. Lu, J. Rinehart, M. Jay and T. Dziubla* “[http://www.ncbi.nlm.nih.gov/pubmed/21190351 Physicochemical Characterization of Nanotemplate Engineered Solid Lipid Nanoparticles]” Langmuir (2010)
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J. Kim, M. Howard, T. Dziubla, J. Rinehart, M. Jay and X. Lu * “[http://www.ncbi.nlm.nih.gov/pubmed/21158414 Uniformity of Drug Payload and its Effect on Stability of Solid Lipid Nanoparticles Containing an Ester Prodrug]” ACS Nano (accepted)
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J. Medley, Heisterberg J, and T Dziubla* “[http://www.ncbi.nlm.nih.gov/pubmed/20573320 Synthesis and Characterization of CREKA-Targeted Polymers for the Disruption of Fibrin Gel Matrix Propagation.]” J Biomater Sci:Poly Ed (E Pub 2010)
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P. Wattamwar, Y. Mo, R. Wan, R. Palli, Q. Zhang and T. Dziubla*, “[http://onlinelibrary.wiley.com/doi/10.1002/adfm.200900839/abstract Antioxidant Activity of Degradable Polymer Poly(trolox ester) to Suppress Oxidative Stress Injury in the Cells.]” Advanced Functional Materials 20:147-154 (2010)
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Y Ma, Y Xiong*, J Zhai, H Zhu, and T Dziubla, “[http://www.ncbi.nlm.nih.gov/pubmed/20352082 Fractionation and Evaluation of Radical Scavenging Peptides from in vitro Digests of Buckwheat Protein.]” Food Chemistry 118:582-588 (2010)
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J. Medley, E. Beane, E. Kaplan and T Dziubla* “[http://www.ncbi.nlm.nih.gov/pubmed/19607939 Block copolymers for the rational design of self-forming postsurgical adhesion barriers.]” Acta Biomaterialia 6:72-82 (2010)
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E Simone*, T Dziubla, D Discher, and V Muzykantov. “[http://www.ncbi.nlm.nih.gov/pubmed/19385657 Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase.]” Biomacromolecules 10:1324-30 (2009)
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E Simone*, T. Dziubla, E Arguiri, V Vardon, V Shuvaev, M Christofidou-Solomidou and V Muzykantov. “[http://www.ncbi.nlm.nih.gov/pubmed/18956141 Loading PEG-catalase into filamentous and spherical polymer nanocarriers]” Pharmaceutical Research 26:250-60 (2009)
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E. Simone, T.D. Dziubla, and V. R Muzykantov., “Polymeric Carriers: Role of Geometry in Drug Delivery.” Expert Opinion on Drug Delivery 5:1283-1300 (2008)
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M. Howard, M Jay, T. Dziubla, X. Lu*, “PEGylation of Nanocarrier Drug Delivery Systems: State of the Art.” J Biomed Nanotech 4:133-148 (2008)
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C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET 325:400-408 (2008)
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T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)
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E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)
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S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov  “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)
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Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006)
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T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)
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T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)
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T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, "Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices." Biomaterials 22, 2893-2899, (2001)

Revision as of 15:17, 17 February 2011

Resources

Protocols
Equipment

  • DLS
  • Glovebox
  • Fluorimeter
  • Freeze Dryer
  • Uv-Vis
  • GPC/HPLC

Materials
Internal

Contact

Thomas Dziubla
Assistant Professor
Mat and Chem Engineering
University of Kentucky
177 F Paul Anderson Tower
Lexington, KY 40506-0046
dziubla-at-engr.uky.edu

M. Howard, X. Lu, J. Rinehart, M. Jay and T. Dziubla* “Physicochemical Characterization of Nanotemplate Engineered Solid Lipid Nanoparticles” Langmuir (2010)

J. Kim, M. Howard, T. Dziubla, J. Rinehart, M. Jay and X. Lu * “Uniformity of Drug Payload and its Effect on Stability of Solid Lipid Nanoparticles Containing an Ester Prodrug” ACS Nano (accepted)

J. Medley, Heisterberg J, and T Dziubla* “Synthesis and Characterization of CREKA-Targeted Polymers for the Disruption of Fibrin Gel Matrix Propagation.” J Biomater Sci:Poly Ed (E Pub 2010)

P. Wattamwar, Y. Mo, R. Wan, R. Palli, Q. Zhang and T. Dziubla*, “Antioxidant Activity of Degradable Polymer Poly(trolox ester) to Suppress Oxidative Stress Injury in the Cells.” Advanced Functional Materials 20:147-154 (2010)

Y Ma, Y Xiong*, J Zhai, H Zhu, and T Dziubla, “Fractionation and Evaluation of Radical Scavenging Peptides from in vitro Digests of Buckwheat Protein.” Food Chemistry 118:582-588 (2010)

J. Medley, E. Beane, E. Kaplan and T Dziubla* “Block copolymers for the rational design of self-forming postsurgical adhesion barriers.” Acta Biomaterialia 6:72-82 (2010)

E Simone*, T Dziubla, D Discher, and V Muzykantov. “Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase.” Biomacromolecules 10:1324-30 (2009)

E Simone*, T. Dziubla, E Arguiri, V Vardon, V Shuvaev, M Christofidou-Solomidou and V Muzykantov. “Loading PEG-catalase into filamentous and spherical polymer nanocarriers” Pharmaceutical Research 26:250-60 (2009)

E. Simone, T.D. Dziubla, and V. R Muzykantov., “Polymeric Carriers: Role of Geometry in Drug Delivery.” Expert Opinion on Drug Delivery 5:1283-1300 (2008)

M. Howard, M Jay, T. Dziubla, X. Lu*, “PEGylation of Nanocarrier Drug Delivery Systems: State of the Art.” J Biomed Nanotech 4:133-148 (2008)

C. Garnacho, R. Dhami, E. Simone, T. Dziubla, J. Leferovich, E. H. Schuchman, V. Muzykantov, and S. Muro*. “Delivery of acid sphingomyelinase in normal and Niemann-Pick disease mice using ICAM-1-targeted polymer nanoparticles” JPET 325:400-408 (2008)

T.D. Dziubla*, V.V. Shuvaev, N.K. Hong, B. Hawkins, M. Muniswamy, H. Takano, E. Simone, M.T. Nakada, A. Fisher, S.M. Albelda, and V.R. Muzykantov, “Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies.” Biomaterials 2:215-27 (2008)

E. Simone*, T. Dziubla, F. Colon, D. Discher and V.R. Muzykantov. “Amphiphilicity of PEG-PLA diblock copolymer controls the formulation and morphology of nanocarriers protecting loaded therapeutic enzyme from proteolysis” Biomacromolecules 8:3914-21 (2007)

S. Muro*, T.D. Dziubla, W. Qui, J. Leferovich, X. Cui, E. Berk and V.R. Muzykantov “Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to ICAM-1.” JPET 317(3):1161-9 (2006)

Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. “Advanced drug delivery systems that target the vascular endothelium.” Mol Interv. 2:98-112 (2006)

T.D. Dziubla*, A. Karim and V. Muzykantov, “Polymer nanocarriers (PNC) protect loaded catalase cargo from proteolysis.” Journal of Controlled Release 102(2), 427-439, (2005)

T.D. Dziubla and A.M. Lowman*, “Vascularization of PEG-grafted macroporous hydrogel sponges: a 3-dimensional in vitro angiogenesis model utilizing human microvascular endothelial cells.” Journal of Biomedical Materials Research. 68A (4): 603-614, (2004)

T.D. Dziubla, M.C. Torjman, J.I. Joseph, M. Murphy-Tatum and A.M. Lowman*, "Evaluation of porous networks of poly(2-hydroxyethyl methacrylate) as interfacial drug delivery devices." Biomaterials 22, 2893-2899, (2001)

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