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This week we will be reading papers about the evolution of gene expression over development. These are two short and provocative papers in Nature ([http://www.nature.com/nature/journal/v468/n7325/full/nature09634.html Kalinka et al], and [http://www.nature.com/nature/journal/v468/n7325/full/nature09632.html Domazet-Lošo, T. & Tautz]). I'm also posting the [http://www.nature.com/nature/journal/v468/n7325/full/468768a.html news & views] to supplement the papers. (Discussion leader - Yaniv Brandvain)
This week we will be reading papers about the evolution of gene expression over development. These are two short and provocative papers in Nature ([http://www.nature.com/nature/journal/v468/n7325/full/nature09634.html Kalinka et al], and [http://www.nature.com/nature/journal/v468/n7325/full/nature09632.html Domazet-Lošo, T. & Tautz]). I'm also posting the [http://www.nature.com/nature/journal/v468/n7325/full/468768a.html news & views] to supplement the papers. (Discussion leader - Yaniv Brandvain)


======Comments======
We are posting comments on this weeks readings [[EDGD_Comments|here]]. The idea is to get the discussion started before we meet, and keep it going after.
(Things to talk about/think about/discuss)
 
 
(:commentbox:)
 
YB1:I'm generally impressed by the consistency of the developmental hourglass (dh) pattern across various categories (phenotypic, expression, age of genes, dN...).
 
There are a few suggested evolutionary explanations for the dh, which do we like?
 
Although we like the dh now Darwin thought things where most similar when youngest. I think this is still viable. How much of the bottom of the hourglass is due t maternal effect genes? Is the thin part of the glass the maternal-zygotic transition?
 
Kalinka et al: The most hourglass like expression was in the genes controlling gene expression, suggesting that this is a top down sort of thing.
 
Loso & Tautz: I'm a bit skeptical of phylostratigraphy, but haven't heard much of it before... any thoughts or comments?


=====1/14/11=====
=====1/14/11=====

Revision as of 15:01, 6 January 2011

Evolutionary genetics discussion group. UC Davis


A reading group for the UC Davis community interested in evolutionary genetics.

Winter 2011

Meetings 12:00 on Fridays. Chucklesworth suite.

1/7/11

This week we will be reading papers about the evolution of gene expression over development. These are two short and provocative papers in Nature (Kalinka et al, and Domazet-Lošo, T. & Tautz). I'm also posting the news & views to supplement the papers. (Discussion leader - Yaniv Brandvain)

We are posting comments on this weeks readings here. The idea is to get the discussion started before we meet, and keep it going after.

1/14/11

Alisa Sedghifar. TBD.

1/21/11

TBD.

Suggestions

Post suggestions for discussion papers or topics here.

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