Ellis:Research: Difference between revisions
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'''Latest Update: April 2010''' | '''Latest Update: April 2010''' | ||
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Research in the Ellis Lab focuses on advancing biotechnology through the use of synthetic biology. Projects | Research in the Ellis Lab focuses on advancing biotechnology through the use of synthetic biology. Projects fall into one of two categories or belong in both: | ||
* '''1. Foundational Synthetic Biology''' | * '''1. Foundational Synthetic Biology''' | ||
Developing the tools for rapid, predictable engineering of biological devices and systems | Developing the tools for rapid, predictable engineering of biological devices and systems. <br> | ||
''Examples: biopart design, assembly techniques and device synthesis, part and device characterisation, standardisation, chassis systems, mathematical models, design simulations'' | ''Examples: biopart design, assembly techniques and device synthesis, part and device characterisation, standardisation, chassis systems, mathematical models, design simulations'' | ||
* '''2. Applied Synthetic Biology''' | * '''2. Applied Synthetic Biology''' | ||
Using the synthetic biology approach in biotechnology applications | Using the synthetic biology approach in biotechnology applications . <br> | ||
''Examples: combinatorial synthesis of | ''Examples: combinatorial synthesis of pathways, modular design of biosensors'' | ||
== Current Projects == | == Current Projects == | ||
'''Investigating device-chassis interactions''' | '''Investigating device-chassis interactions'''<br> | ||
Project Type: ''Foundational'' | Project Type: ''Foundational''<br> | ||
Project Members: ''Rhys Algar'' | Project Members: ''Rhys Algar''<br> | ||
Collaborators: ''Guy-Bart Stan'' | Collaborators: ''Guy-Bart Stan''<br> | ||
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in ''E.coli''. | Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in ''E.coli''. | ||
'''Combinatorial assembly of a regulated Lycopene production pathway in yeast ''' | '''Combinatorial assembly of a regulated Lycopene production pathway in yeast'''<br> | ||
Project Type: ''Foundational'' ''Applied'' | Project Type: ''Foundational'' ''Applied''<br> | ||
Project Members: ''Tom Ellis'' | Project Members: ''Tom Ellis''<br> | ||
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number | Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number stuff. |
Revision as of 23:58, 8 April 2010
Latest Update: April 2010
Research in the Ellis Lab focuses on advancing biotechnology through the use of synthetic biology. Projects fall into one of two categories or belong in both:
- 1. Foundational Synthetic Biology
Developing the tools for rapid, predictable engineering of biological devices and systems.
Examples: biopart design, assembly techniques and device synthesis, part and device characterisation, standardisation, chassis systems, mathematical models, design simulations
- 2. Applied Synthetic Biology
Using the synthetic biology approach in biotechnology applications .
Examples: combinatorial synthesis of pathways, modular design of biosensors
Current Projects
Investigating device-chassis interactions
Project Type: Foundational
Project Members: Rhys Algar
Collaborators: Guy-Bart Stan
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in E.coli.
Combinatorial assembly of a regulated Lycopene production pathway in yeast
Project Type: Foundational Applied
Project Members: Tom Ellis
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number stuff.