Ellis:Research: Difference between revisions

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* '''1. Foundational Synthetic Biology'''
* '''1. Foundational Synthetic Biology'''
Developing the tools for rapid, predictable engineering of biological devices and systems. <br>
Developing the tools for rapid, predictable engineering of biological devices and systems. <br>
''Examples: biopart design, assembly techniques and device synthesis, part and device characterisation, standardisation, chassis systems, mathematical models, design simulations''
 
''Examples: biopart design, assembly techniques and device synthesis, part and device characterisation, standardisation, chassis systems, mathematical models, design simulations''<br>


* '''2. Applied Synthetic Biology'''
* '''2. Applied Synthetic Biology'''
Using the synthetic biology approach in biotechnology applications . <br>
Using the synthetic biology approach in biotechnology applications . <br>
''Examples: combinatorial synthesis of pathways, modular design of biosensors''
''Examples: combinatorial synthesis of pathways, modular design of biosensors''


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Project Members: ''Rhys Algar''<br>
Project Members: ''Rhys Algar''<br>
Collaborators: ''Guy-Bart Stan''<br>
Collaborators: ''Guy-Bart Stan''<br>
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in ''E.coli''.  
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in ''E.coli''. To expand


'''Combinatorial assembly of a regulated Lycopene production pathway in yeast'''<br>
'''Combinatorial assembly of a regulated Lycopene production pathway in yeast'''<br>
Project Type: ''Foundational'' ''Applied''<br>
Project Type: ''Foundational'' ''Applied''<br>
Project Members: ''Tom Ellis''<br>
Project Members: ''Tom Ellis''<br>
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number stuff.
Describe

Revision as of 00:05, 9 April 2010

Latest Update: April 2010


Research in the Ellis Lab focuses on advancing biotechnology through the use of synthetic biology. Projects fall into one of two categories or belong in both:

  • 1. Foundational Synthetic Biology

Developing the tools for rapid, predictable engineering of biological devices and systems.

Examples: biopart design, assembly techniques and device synthesis, part and device characterisation, standardisation, chassis systems, mathematical models, design simulations

  • 2. Applied Synthetic Biology

Using the synthetic biology approach in biotechnology applications .

Examples: combinatorial synthesis of pathways, modular design of biosensors


Current Projects

Investigating device-chassis interactions
Project Type: Foundational
Project Members: Rhys Algar
Collaborators: Guy-Bart Stan
Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in E.coli. To expand

Combinatorial assembly of a regulated Lycopene production pathway in yeast
Project Type: Foundational Applied
Project Members: Tom Ellis
Describe