Latest Update: April 2010
Research in the Ellis Lab focuses on advancing biotechnology through the use of synthetic biology. Projects in the Ellis Lab fall into one of two categories or belong in both:
- 1. Foundational Synthetic Biology
Developing the tools for rapid, predictable engineering of biological devices and systems Examples: biopart design, assembly techniques and device synthesis, part and device characterisation, standardisation, chassis systems, mathematical models, design simulations
- 2. Applied Synthetic Biology
Using the synthetic biology approach in biotechnology applications Examples: combinatorial synthesis of regulated metabolic pathways, modular design of biosensors
Investigating device-chassis interactions Project Type: Foundational Project Members: Rhys Algar Collaborators: Guy-Bart Stan Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in E.coli.
Combinatorial assembly of a regulated Lycopene production pathway in yeast Project Type: Foundational Applied Project Members: Tom Ellis Most gene devices demonstrated in synthetic biology have been high-expression strength regulatory networks hosted on mid-to-high copy number plasmids in E.coli.