Farre Lab

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Research Our goal is to understand how circadian clocks work and why they play such a key role in growth and development. We study the regulation and role of circadian rhythms in plants, which as sessile and autotrophic organisms rely heavily on daily and seasonal changes for their development and growth. Recent findings show that the appropriate resonance of internal rhythms with daily environmental rhythms optimizes plant growth and survival. During the last few years, a large number of clock components have been identified in plants. However, knowledge of the molecular mechanisms involved in plant circadian clocks lags behind studies in other organisms such as Drosophila and Cyanobacteria. Although circadian clocks share a basic architecture among different taxa, they differ in their molecular components. Thus the study of circadian rhythms in plants will help define not only their role on plant specific processes but also the design principles of circadian oscillators. read more...

Lab Members Eva Farre Tomomi Takeuchi Linsey Newton Tiffany Liu Saundra Mason Andrew Lapinsky Cary Krug Eric Poliner Sam Ballard Open Positions: Undergraduate assistant

Publications Vieler et al. (2012) Genome, Functional Gene Annotation, and Nuclear Transformation of the Heterokont Oleaginous Alga Nannochloropsis oceanica CCMP1779. Plos Genetics8(11):e1003064. Pubmed Farré EM, Weise SE (2012) The interactions between the circadian clock and primary metabolism. Curr Opin Plant Biol 15(3):293-300. PubMed Farre EM (2012) The regulation of plant growth by the circadian clock. Plant Biol 14(3):401-10.PubMed Nusinow DA, Helfer A, Hamilton EE, King JJ, Imaizumi T, Schultz TF, Farré EM, Kay SA (2011) The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth. Nature 475:398-402.PubMed Dong M, Farre EM, Thomashow MF (2011) CIRCADIAN CLOCK-ASSOCIATED 1 and LATE ELONGATED HYPOCOTYL regulate expression of the C-REPEAT BINDING FACTOR (CBF) pathway in Arabidopsis. PNAS 108(17):7241-6.PubMed Farre EM and Kay SA (2007) PRR7 Protein levels are regulated by light and the circadian clock in Arabidopsis. Plant J 52 (3):548–560. Para A, Farre EM, Imaizumi T, Pruneda-Paz J, Harmon FG, Kay SA (2007). PRR3 is a vascular regulator of TOC1 stability in the Arabidopsis circadian clock. Plant Cell 19:3462-3473. Zeilinger MN, Farre EM, Taylor SR, Kay SA and Doyle FJ III (2006) A novel computational model of the circadian clock in Arabidopsis that incorporates PRR7 and PRR9. Mol Syst Biol 2: 58. Farre EM, Harmer SL, Harmon FG, Yanovsky MJ, Kay SA. (2005) Overlapping and distinct roles of PRR7 and PRR9 in the Arabidopsis circadian clock. Curr Biol 15(1):47-54. see complete list...

Announcements Group meeting, journal clubs, and seminars Our Lab has moved to the new Plant Molecular Science Building Tiffany has been awarded a CNS Dissertation Continuation Fellowship. Congratulations!

Links Farre Lab NSF funded Research & Teaching program for pre-service teachers MSU Links Other Circadian Labs Plant Genomics Undergraduate Program at MSU Tools Other Interesting Links Rhythm Movies Gardening Tips http://www.openwetware.org http://openwetware.org/images/0/01/80x15_openwetware.png Funding NSF MSU